Donovan, Katherine F.
1417  Ergebnisse:
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6

C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies t..:

Le Bihan, Yann-Vaï ; Lanigan, Rachel M ; Atrash, Butrus...
Le Bihan , Y-V , Lanigan , R M , Atrash , B , McLaughlin , M G , Velupillai , S , Malcolm , A G , England , K S , Ruda , G F , Mok , N Y , Tumber , A , Tomlin , K , Saville , H , Shehu , E , McAndrew , C , Carmichael , L , Bennett , J M , Jeganathan , F , Eve , P , Donovan , A , Hayes , A , Wood , F , Raynaud , F I , Fedorov , O , Brennan , P , Burke , R , van Montfort , R L M , Rossanese , O W , Blagg , J & Bavetsias , V 2019 , ' C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays ' , European Journal of Medicinal Chemistry , vol. 177 , pp. 316-337 . https://doi.org/10.1016/j.ejmech.2019.05.041.  , 2019
 
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8-substituted pyrido[3,4- d ]pyrimidin-4(3 H )-one derivati..:

Bavetsias, Vassilios ; Lanigan, Rachel M ; Ruda, Gian Filippo...
Bavetsias , V , Lanigan , R M , Ruda , G F , Atrash , B , McLaughlin , M G , Tumber , A , Mok , N Y , Le Bihan , Y V , Dempster , S , Boxall , K J , Jeganathan , F , Hatch , S B , Savitsky , P , Velupillai , S , Krojer , T , England , K S , Sejberg , J , Thai , C , Donovan , A , Pal , A , Scozzafava , G , Bennett , J M , Kawamura , A , Johansson , C , Szykowska , A , Gileadi , C , Burgess-Brown , N A , Von Delft , F , Oppermann , U , Walters , Z , Shipley , J , Raynaud , F I , Westaway , S M , Prinjha , R K , Fedorov , O , Burke , R , Schofield , C J , Westwood , I M , Bountra , C , Müller , S , Van Montfort , R L M , Brennan , P E & Blagg , J 2016 , ' 8-substituted pyrido[3,4- d ]pyrimidin-4(3 H )-one derivatives as potent, cell permeable, KDM4 (JMJD2) and KDM5 (JARID1) histone lysine demethylase inhibitors ' , Journal of Medicinal Chemistry , vol. 59 , no. 4 , pp. 1388-1409 . https://doi.org/10.1021/acs.jmedchem.5b01635.  , 2016
 
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Effects of Beneficial Mutations in pykF Gene Vary over Time..:

Peng, Fen ; Widmann, Scott ; Wünsche, Andrea...
Molecular Biology and Evolution.  35 (2017)  1 - p. 202-210 , 2017
 
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Grappling with anisotropic data, pseudo-merohedral twinning..:

Donovan, Katherine A. ; Atkinson, Sarah C. ; Kessans, Sarah A....
Acta Crystallographica Section D Structural Biology.  72 (2016)  4 - p. 512-519 , 2016
 
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15

The purification, crystallization and preliminary X-ray dif..:

Oliver, Michael R. ; Crowther, Jennifer M. ; Leeman, Mary M....
Acta Crystallographica Section F Structural Biology Communications.  70 (2014)  5 - p. 663-668 , 2014
 
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