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Kobilka, Brian K.
508  Ergebnisse:
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1

A µ-opioid receptor modulator that works cooperatively with..:

O'Brien, Evan S. ; Rangari, Vipin Ashok ; El Daibani, Amal...
Nature.  631 (2024)  8021 - p. 686-693 , 2024
Link: https://doi.org/10.1038/..
 
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2

Negative allosteric modulation of the µ-opioid receptor:

O'Brien, Evan S. ; Rangari, Vipin A. ; El Daibani, Amal...
Biophysical Journal.  123 (2024)  3 - p. 353a , 2024
Link: https://doi.org/10.1016/..
 
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3

Time-resolved cryo-EM of G-protein activation by a GPCR:

Papasergi-Scott, Makaía M. ; Pérez-Hernández, Guillermo ; Batebi, Hossein...
Nature.  629 (2024)  8014 - p. 1182-1191 , 2024
Link: https://doi.org/10.1038/..
 
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4

Mechanistic insights into G-protein coupling with an agonis..:

Batebi, Hossein ; Pérez-Hernández, Guillermo ; Rahman, Sabrina N....
Nature Structural & Molecular Biology.  , 2024
Link: https://doi.org/10.1038/..
 
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5

Author Correction: Stepwise activation of a metabotropic gl..:

Krishna Kumar, Kaavya ; Wang, Haoqing ; Habrian, Chris...
Nature.  629 (2024)  8013 - p. E13-E13 , 2024
Link: https://doi.org/10.1038/..
 
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6

Ligand efficacy modulates conformational dynamics of the µ-..:

Zhao, Jiawei ; Elgeti, Matthias ; O'Brien, Evan S....
Nature.  629 (2024)  8011 - p. 474-480 , 2024
Link: https://doi.org/10.1038/..
 
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7

Stepwise activation of a metabotropic glutamate receptor:

Krishna Kumar, Kaavya ; Wang, Haoqing ; Habrian, Chris...
Nature.  629 (2024)  8013 - p. 951-956 , 2024
Link: https://doi.org/10.1038/..
 
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8

Negative allosteric modulation of the glucagon receptor by ..:

O'Brien, Evan S. ; Krishna Kumar, Kaavya ; Habrian, Chris...
Biophysical Journal.  122 (2023)  3 - p. 161a , 2023
Link: https://doi.org/10.1016/..
 
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9

Structural and dynamic insights into supra-physiological ac..:

Xu, Jun ; Wang, Qinggong ; Hübner, Harald...
Nature Communications.  14 (2023)  1 - p. , 2023
Link: https://doi.org/10.1038/..
 
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10

Arrestin C-tail dynamics regulate activation and GPCR engag..:

Janetzko, John ; Inoue, Asuka ; Shi, Yuqi...
Biophysical Journal.  122 (2023)  3 - p. 49a , 2023
Link: https://doi.org/10.1016/..
 
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11

Negative allosteric modulation of the glucagon receptor by ..:

Krishna Kumar, Kaavya ; O'Brien, Evan S. ; Habrian, Chris H....
Cell.  186 (2023)  7 - p. 1465-1477.e18 , 2023
Link: https://doi.org/10.1016/..
 
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12

Structural basis for activation of CB1 by an endocannabinoi..:

Krishna Kumar, Kaavya ; Robertson, Michael J. ; Thadhani, Elina...
Nature Communications.  14 (2023)  1 - p. , 2023
Link: https://doi.org/10.1038/..
 
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13

Author Correction: Constrained catecholamines gain β2AR sel..:

Xu, Xinyu ; Shonberg, Jeremy ; Kaindl, Jonas...
Nature Communications.  14 (2023)  1 - p. , 2023
Link: https://doi.org/10.1038/..
 
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14

Function and dynamics of the intrinsically disordered carbo..:

Heng, Jie ; Hu, Yunfei ; Pérez-Hernández, Guillermo...
Nature Communications.  14 (2023)  1 - p. , 2023
Link: https://doi.org/10.1038/..
 
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15

Molecular determinants of ligand efficacy and potency in GP..:

Heydenreich, Franziska M. ; Marti-Solano, Maria ; Sandhu, Manbir...
Science.  382 (2023)  6677 - p. , 2023
Link: https://doi.org/10.1126/..
 
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