E-LIB Suche - Ergebnisse für: Thoma, Gebhard

1

Modelling atopic dermatitis in healthy human skin for the c..:

Hacini‐Rachinel, Feriel ; Hauchard, Alice ; Bruno, Sandro...
Experimental Dermatology. 33 (2024) 5 - p. , 2024

2

Structure-Guided Elaboration of a Fragment-Like Hit into an..:

Thoma, Gebhard ; Miltz, Wolfgang ; Srinivas, Honnappa...
Journal of Medicinal Chemistry. 67 (2024) 6 - p. 5093-5108 , 2024

Link: https://doi.org/10.1021/..

3

LTA4H inhibitor LYS006: Clinical PK/PD and safety in a rand..:

Loesche, Christian ; Picard, Damien ; Van Hoorick, Benjamin...
Clinical and Translational Science. 17 (2024) 2 - p. , 2024

Link: https://doi.org/10.1111/..

4

Structure-Guided Elaboration of a Fragment-Like Hit into an..:

Gebhard Thoma ; Wolfgang Miltz ; Honnappa Srinivas...
https://figshare.com/articles/dataset/Structure-Guided_Elaboration_of_a_Fragment-Like_Hit_into_an_Orally_Efficacious_Leukotriene_A4_Hydrolase_Inhibitor/25397577. , 2024

Link: https://doi.org/10.1021/..

5

Structure-Guided Elaboration of a Fragment-Like Hit into an..:

Gebhard Thoma ; Wolfgang Miltz ; Honnappa Srinivas...
https://figshare.com/articles/journal_contribution/Structure-Guided_Elaboration_of_a_Fragment-Like_Hit_into_an_Orally_Efficacious_Leukotriene_A4_Hydrolase_Inhibitor/25397574. , 2024

Link: https://doi.org/10.1021/..

6

Discovery and Characterization of the Topical Soft JAK Inhi..:

Thoma, Gebhard ; Duthaler, Rudolf O. ; Waelchli, Rudolf...
Journal of Medicinal Chemistry. 66 (2023) 3 - p. 2161-2168 , 2023

Link: https://doi.org/10.1021/..

7

Discovery of Amino Alcohols as Highly Potent, Selective, an..:

Thoma, Gebhard ; Markert, Christian ; Lueoend, Rainer...
Journal of Medicinal Chemistry. 66 (2023) 23 - p. 16410-16425 , 2023

Link: https://doi.org/10.1021/..

8

Design of a Supersoft Topical JAK Inhibitor, Which Is Effec..:

Thoma, Gebhard ; Decoret, Odile ; Vangrevelinghe, Eric...
Journal of Medicinal Chemistry. 66 (2023) 21 - p. 15042-15053 , 2023

Link: https://doi.org/10.1021/..

9

Novel Concept for Super-Soft Topical Drugs: Deactivation by..:

Thoma, Gebhard ; Vangrevelinghe, Eric ; Luneau, Alexandre...
ACS Medicinal Chemistry Letters. 14 (2023) 6 - p. 841-845 , 2023

Link: https://doi.org/10.1021/..

10

Discovery of Amino Alcohols as Highly Potent, Selective, an..:

Gebhard Thoma ; Christian Markert ; Rainer Lueoend...
doi:10.1021/acs.jmedchem.3c01866.s001. , 2023

Link: https://doi.org/10.1021/..

11

Discovery of Amino Alcohols as Highly Potent, Selective, an..:

Gebhard Thoma ; Christian Markert ; Rainer Lueoend...
doi:10.1021/acs.jmedchem.3c01866.s002. , 2023

Link: https://doi.org/10.1021/..

12

Discovery of LYS006, a Potent and Highly Selective Inhibito..:

Markert, Christian ; Thoma, Gebhard ; Srinivas, Honnappa...
Journal of Medicinal Chemistry. 64 (2021) 4 - p. 1889-1903 , 2021

Link: https://doi.org/10.1021/..

13

Discovery and Profiling of a Selective and Efficacious Syk ..:

Thoma, Gebhard ; Smith, Alexander B. ; van Eis, Maurice J....
Journal of Medicinal Chemistry. 58 (2015) 4 - p. 1950-1963 , 2015

Link: https://doi.org/10.1021/..

14

Orally bioavailable Syk inhibitors with activity in a rat P..:

Thoma, Gebhard ; Veenstra, Siem ; Strang, Ross...
Bioorganic & Medicinal Chemistry Letters. 25 (2015) 20 - p. 4642-4647 , 2015

Link: https://doi.org/10.1016/..

15

Syk inhibitors with high potency in presence of blood:

Thoma, Gebhard ; Blanz, Joachim ; Bühlmayer, Peter...
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 10 - p. 2278-2282 , 2014

Link: https://doi.org/10.1016/..