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Möhrle, Jörg
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1

How long does it take to develop a new drug?:

Möhrle, Jörg J.
The Lancet Regional Health - Europe.  43 (2024)  - p. 100998 , 2024
Link: https://doi.org/10.1016/..
 
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2

Development and application of a PBPK modeling strategy to ..:

Abla, Nada ; Howgate, Eleanor ; Rowland‐Yeo, Karen...
CPT: Pharmacometrics & Systems Pharmacology.  12 (2023)  9 - p. 1335-1346 , 2023
Link: https://doi.org/10.1002/..
 
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3

Using Cryopreserved Plasmodium falciparum Sporozoites in a ..:

Jiménez-Díaz, María-Belén ; Möhrle, Jörg J. ; Angulo-Barturen, Iñigo.
Microorganisms.  11 (2023)  9 - p. 2209 , 2023
Link: https://doi.org/10.3390/..
 
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4

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic..:

Chughlay, M. Farouk ; Barnes, Karen I. ; El Gaaloul, Myriam...
Antimicrobial Agents and Chemotherapy.  66 (2022)  1 - p. , 2022
Link: https://doi.org/10.1128/..
 
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5

Model-informed target product profiles of long-acting-injec..:

Burgert, Lydia ; Reiker, Theresa ; Golumbeanu, Monica...
PLOS Global Public Health.  2 (2022)  3 - p. e0000211 , 2022
Link: https://doi.org/10.1371/..
 
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6

A pharmacokinetic–pharmacodynamic model for chemoprotective..:

Cherkaoui‐Rbati, Mohammed H. ; Andenmatten, Nicole ; Burgert, Lydia...
CPT: Pharmacometrics & Systems Pharmacology.  12 (2022)  1 - p. 50-61 , 2022
Link: https://doi.org/10.1002/..
 
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7

NewIn VitroInteraction-Parasite Reduction Ratio Assay for E..:

Wicha, Sebastian G. ; Walz, Annabelle ; Cherkaoui-Rbati, Mohammed H....
Antimicrobial Agents and Chemotherapy.  66 (2022)  11 - p. , 2022
Link: https://doi.org/10.1128/..
 
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8

Parasite Viability as a Measure ofIn VivoDrug Activity in P..:

Radohery, Georges F. R. ; Walz, Annabelle ; Gumpp, Christin...
Antimicrobial Agents and Chemotherapy.  66 (2022)  7 - p. , 2022
Link: https://doi.org/10.1128/..
 
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9

Safety, Tolerability, and Parasite Clearance Kinetics in Co..:

Chughlay, M. Farouk ; Chalon, Stephan ; El Gaaloul, Myriam...
The American Journal of Tropical Medicine and Hygiene.  107 (2022)  4 - p. 804-814 , 2022
Link: https://doi.org/10.4269/..
 
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10

Cytochrome P450-Mediated Metabolism and CYP Inhibition for ..:

Shackleford, David M. ; Chiu, Francis C. K. ; Katneni, Kasiram...
ACS Infectious Diseases.  7 (2021)  7 - p. 1885-1893 , 2021
Link: https://doi.org/10.1021/..
 
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11

Towards the next generation of antimalaria combination ther..:

Möhrle, Jörg J
The Lancet Infectious Diseases.  21 (2021)  12 - p. 1620-1621 , 2021
Link: https://doi.org/10.1016/..
 
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12

First‐in‐human clinical trial to assess the safety, tolerab..:

Chughlay, M. Farouk ; Rossignol, Emilie ; Donini, Cristina...
British Journal of Clinical Pharmacology.  86 (2020)  6 - p. 1113-1124 , 2020
Link: https://doi.org/10.1111/..
 
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13

Safety and parasite clearance of artemisinin-resistant Plas..:

Watts, Rebecca E. ; Odedra, Anand ; Marquart, Louise...
PLOS Medicine.  17 (2020)  8 - p. e1003203 , 2020
Link: https://doi.org/10.1371/..
 
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14

Antimalarial Activity of Artefenomel Against Asexual Parasi..:

Collins, Katharine A ; Abd-Rahman, Azrin N ; Marquart, Louise...
The Journal of Infectious Diseases.  225 (2020)  6 - p. 1062-1069 , 2020
Link: https://doi.org/10.1093/..
 
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15

Ensemble modeling highlights importance of understanding pa..:

Burgert, Lydia ; Rottmann, Matthias ; Wittlin, Sergio...
Scientific Reports.  10 (2020)  1 - p. , 2020
Link: https://doi.org/10.1038/..
 
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