E-LIB Suche - Ergebnisse für: Newell, David R.

1

Parallel Optimization of Potency and Pharmacokinetics Leadi..:

Miller, Duncan C. ; Reuillon, Tristan ; Molyneux, Lauren...
Journal of Medicinal Chemistry. 65 (2022) 9 - p. 6513-6540 , 2022

Link: https://doi.org/10.1021/..

2

Structure-Based Design of Potent and Orally Active Isoindol..:

Chessari, Gianni ; Hardcastle, Ian R. ; Ahn, Jong Sook...
Journal of Medicinal Chemistry. 64 (2021) 7 - p. 4071-4088 , 2021

Link: https://doi.org/10.1021/..

3

2-Arylamino-6-ethynylpurines are cysteine-targeting irrever..:

Matheson, Christopher J. ; Coxon, Christopher R. ; Bayliss, Richard...
RSC Medicinal Chemistry. 11 (2020) 6 - p. 707-731 , 2020

Link: https://doi.org/10.1039/..

4

A successful collaboration between academia, biotech and ph..:

Murray, Christopher W. ; Newell, David R. ; Angibaud, Patrick
MedChemComm. 10 (2019) 9 - p. 1509-1511 , 2019

Link: https://doi.org/10.1039/..

5

Identification of a novel orally bioavailable ERK5 inhibito..:

Myers, Stephanie M. ; Miller, Duncan C. ; Molyneux, Lauren...
European Journal of Medicinal Chemistry. 178 (2019) - p. 530-543 , 2019

Link: https://doi.org/10.1016/..

6

Preclinical evaluation of the first intravenous small molec..:

Chen, Lindi ; Pastorino, Fabio ; Berry, Philip...
International Journal of Cancer. 144 (2019) 12 - p. 3146-3159 , 2019

Link: https://doi.org/10.1002/..

7

Selective DNA-PKcs inhibition extends the therapeutic index..:

Willoughby, Catherine E. ; Jiang, Yanyan ; Thomas, Huw D....
Journal of Clinical Investigation. 130 (2019) 1 - p. 258-271 , 2019

Link: https://doi.org/10.1172/..

8

Highly Potent Clickable Probe for Cellular Imaging of MDM2 ..:

Lebraud, Honorine ; Noble, Richard A. ; Phillips, Nicole...
Bioconjugate Chemistry. 29 (2018) 6 - p. 2100-2106 , 2018

Link: https://doi.org/10.1021/..

9

Sensitizing Ewing sarcoma to chemo- and radiotherapy by inh..:

Vormoor, Britta ; Schlosser, Yvonne T. ; Blair, Helen...
Oncotarget. 8 (2017) 69 - p. 113418-113430 , 2017

Link: https://doi.org/10.18632..

10

PARP inhibitor rucaparib induces changes in NAD levels in c..:

Almeida, Gilberto S. ; Bawn, Carlo M. ; Galler, Martin...
NMR in Biomedicine. 30 (2017) 9 - p. , 2017

Link: https://doi.org/10.1002/..

11

Cyclin-Dependent Kinase (CDK) Inhibitors: Structure–Activit..:

Coxon, Christopher R. ; Anscombe, Elizabeth ; Harnor, Suzannah J....
Journal of Medicinal Chemistry. 60 (2017) 5 - p. 1746-1767 , 2017

Link: https://doi.org/10.1021/..

12

TP53 mutant MDM2-amplified cell lines selected for resistan..:

Drummond, Catherine J. ; Esfandiari, Arman ; Liu, Junfeng...
Oncotarget. 7 (2016) 29 - p. 46203-46218 , 2016

Link: https://doi.org/10.18632..

13

Combined PI3K and CDK2 inhibition induces cell death and en..:

Beale, Gary ; Haagensen, Emma J ; Thomas, Huw D...
British Journal of Cancer. 115 (2016) 6 - p. 682-690 , 2016

Link: https://doi.org/10.1038/..

14

High-Throughput Screening and Hit Validation of Extracellul..:

Myers, Stephanie M. ; Bawn, Ruth H. ; Bisset, Louise C....
ACS Combinatorial Science. 18 (2016) 8 - p. 444-455 , 2016

Link: https://doi.org/10.1021/..

15

Design and synthesis of biphenyl and biphenyl ether inhibit..:

Reuillon, Tristan ; Alhasan, Sari F. ; Beale, Gary S....
Chemical Science. 7 (2016) 4 - p. 2821-2826 , 2016

Link: https://doi.org/10.1039/..