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Brown, Christopher R
35875  Ergebnisse:
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1

RNAi-mediated rheostat for dynamic control of AAV-delivered..:

Subramanian, Megha ; McIninch, James ; Zlatev, Ivan...
Nature Communications.  14 (2023)  1 - p. , 2023
Link: https://doi.org/10.1038/..
 
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2

Palmitoylation Regulates Human Serotonin Transporter Activi..:

Brown, Christopher R. ; Foster, James D.
ACS Chemical Neuroscience.  14 (2023)  18 - p. 3431-3443 , 2023
Link: https://doi.org/10.1021/..
 
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3

Development of a selection assay for small guide RNAs that ..:

Diaz Quiroz, Juan Felipe ; Ojha, Namrata ; Shayhidin, Elnur E...
Nucleic Acids Research.  51 (2023)  7 - p. e41-e41 , 2023
Link: https://doi.org/10.1093/..
 
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4

From bench to bedside: Improving the clinical safety of Gal..:

Schlegel, Mark K ; Janas, Maja M ; Jiang, Yongfeng...
Nucleic Acids Research.  50 (2022)  12 - p. 6656-6670 , 2022
Link: https://doi.org/10.1093/..
 
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5

Overcoming GNA/RNA base-pairing limitations using isonucleo..:

Schlegel, Mark K ; Matsuda, Shigeo ; Brown, Christopher R...
Nucleic Acids Research.  49 (2021)  19 - p. 10851-10867 , 2021
Link: https://doi.org/10.1093/..
 
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6

Leakage pressures for gasketless superhydrophobic fluid int..:

Brown, Christopher R. ; Zhao, Xiaoxiao ; Park, Taehyun...
Microsystems & Nanoengineering.  7 (2021)  1 - p. , 2021
Link: https://doi.org/10.1038/..
 
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7

Chirality matters: stereo-defined phosphorothioate linkages..:

Jahns, Hartmut ; Taneja, Nate ; Willoughby, Jennifer L S...
Nucleic Acids Research.  50 (2021)  3 - p. 1221-1240 , 2021
Link: https://doi.org/10.1093/..
 
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8

Small circular interfering RNAs (sciRNAs) as a potent thera..:

Jahns, Hartmut ; Degaonkar, Rohan ; Podbevsek, Peter...
Nucleic Acids Research.  49 (2021)  18 - p. 10250-10264 , 2021
Link: https://doi.org/10.1093/..
 
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9

Investigating the pharmacodynamic durability of GalNAc–siRN..:

Brown, Christopher R ; Gupta, Swati ; Qin, June...
Nucleic Acids Research.  48 (2020)  21 - p. 11827-11844 , 2020
Link: https://doi.org/10.1093/..
 
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10

Safety evaluation of 2′-deoxy-2′-fluoro nucleotides in GalN..:

Janas, Maja M ; Zlatev, Ivan ; Liu, Ju...
Nucleic Acids Research.  47 (2019)  7 - p. 3306-3320 , 2019
Link: https://doi.org/10.1093/..
 
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11

The TAFs of TFIID Bind and Rearrange the Topology of the TA..:

Le, Sarah N. ; Brown, Christopher R. ; Harvey, Stacy...
International Journal of Molecular Sciences.  20 (2019)  13 - p. 3290 , 2019
Link: https://doi.org/10.3390/..
 
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12

5′-Morpholino modification of the sense strand of an siRNA ..:

Kumar, Pawan ; Parmar, Rubina G. ; Brown, Christopher R....
Chemical Communications.  55 (2019)  35 - p. 5139-5142 , 2019
Link: https://doi.org/10.1039/..
 
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13

Facile Synthesis, Geometry, and 2′-Substituent-Dependent in..:

Parmar, Rubina Giare ; Brown, Christopher R. ; Matsuda, Shigeo...
Journal of Medicinal Chemistry.  61 (2018)  3 - p. 734-744 , 2018
Link: https://doi.org/10.1021/..
 
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14

Reversal of siRNA-mediated gene silencing in vivo:

Zlatev, Ivan ; Castoreno, Adam ; Brown, Christopher R...
Nature Biotechnology.  36 (2018)  6 - p. 509-511 , 2018
Link: https://doi.org/10.1038/..
 
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15

Advanced siRNA Designs Further Improve In Vivo Performance ..:

Foster, Donald J. ; Brown, Christopher R. ; Shaikh, Sarfraz...
Molecular Therapy.  26 (2018)  3 - p. 708-717 , 2018
Link: https://doi.org/10.1016/..
 
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