E-LIB Suche - Ergebnisse für: Koovits, Paul J

1

Hit-to-lead optimization of a benzene sulfonamide series fo..:

Koovits, Paul J ; Dessoy, Marco A ; Matheeussen, An...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126888/. , 2020

2

Conformationally Driven Two- and Three-Photon Cascade Proce..:

Koovits, Paul ; Knowles, Jonathan ; Booker-Milburn, Kevin
Koovits , P , Knowles , J & Booker-Milburn , K 2016 , ' Conformationally Driven Two- and Three-Photon Cascade Processes in the Stereoselective Photorearrangement of Pyrroles ' , Organic Letters , vol. 18 , no. 21 , pp. 5608-5611 . https://doi.org/10.1021/acs.orglett.6b02829. , 2016

Link: https://hdl.handle.net/1..

3

2-aminobenzimidazoles for leishmaniasis: From initial hit d..:

Rafael Augusto Alves Ferreira ; Celso de Oliveira Rezende Junior ; Pablo David Grigol Martinez...
https://doi.org/10.1371/journal.pntd.0009196. , 2021

Link: https://doi.org/10.1371/..

4

Proof of concept in vivo activity in a VL acute model:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/Proof_of_concept_in_vivo_activity_in_a_VL_acute_model_/14078755. , 2021

Link: https://doi.org/10.1371/..

5

Chemical structure, initial hit assessment data and metabol..:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/Chemical_structure_initial_hit_assessment_data_and_metabolic_soft_spots_for_compound_1_/14078728. , 2021

Link: https://doi.org/10.1371/..

6

Complete biological dataset:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/dataset/Complete_biological_dataset_/14078722. , 2021

Link: https://doi.org/10.1371/..

7

In vitro profiling of analogues with modifications at the N..:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/In_vitro_profiling_of_analogues_with_modifications_at_the_N-alkyl_chain_/14078740. , 2021

Link: https://doi.org/10.1371/..

8

In vitro profiling of analogues with additional modificatio..:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/In_vitro_profiling_of_analogues_with_additional_modifications_at_the_benzimidazole_core_and_side_chain_/14078746. , 2021

Link: https://doi.org/10.1371/..

9

Synthesis of purine 56:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/Synthesis_of_purine_56_/14078734. , 2021

Link: https://doi.org/10.1371/..

10

Summary of SARs and SPRs for 2-aminobenzimidazole derivativ..:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/Summary_of_SARs_and_SPRs_for_2-aminobenzimidazole_derivatives_/14078752. , 2021

Link: https://doi.org/10.1371/..

11

Detailed synthetic and spectral information:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/journal_contribution/Detailed_synthetic_and_spectral_information_/14078725. , 2021

Link: https://doi.org/10.1371/..

12

Synthesis of 2-aminobenzimidazoles:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/Synthesis_of_2-aminobenzimidazoles_/14078731. , 2021

Link: https://doi.org/10.1371/..

13

In vitro profiling of analogues with modifications in the b..:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/In_vitro_profiling_of_analogues_with_modifications_in_the_benzimidazole_ring_/14078737. , 2021

Link: https://doi.org/10.1371/..

14

In vitro profiling of analogues with modifications at the a..:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/In_vitro_profiling_of_analogues_with_modifications_at_the_amide_group_/14078743. , 2021

Link: https://doi.org/10.1371/..

15

Summary of in vitro ADME and in vivo PK data for selected c..:

Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/dataset/Summary_of_in_vitro_ADME_and_in_vivo_PK_data_for_selected_compounds_/14078758. , 2021

Link: https://doi.org/10.1371/..