Mogg, Adrian J
30  Ergebnisse:
Personensuche X
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Biased M1-muscarinic-receptor-mutant mice inform the design..:

Bradley, Sophie J ; Molloy, Colin ; Valuskova, Paulina...
Bradley , S J , Molloy , C , Valuskova , P , Dwomoh , L , Scarpa , M , Rossi , M , Finlayson , L , Svensson , K A , Chernet , E , Barth , V N , Gherbi , K , Sykes , D A , Wilson , C A , Mistry , R , Sexton , P M , Christopoulos , A , Mogg , A J , Rosethorne , E M , Sakata , S , John Challiss , R A , Broad , L M & Tobin , A B 2020 , ' Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs ' , Nature Chemical Biology , vol. 16 , no. 3 , pp. 240-249 . https://doi.org/10.1038/s41589-019-0453-9.  , 2020
 
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Bitopic binding mode of an M 1 muscarinic acetylcholine rec..:

Bradley, Sophie J ; Molloy, Colin ; Bundgaard, Christoffer...
Bradley , S J , Molloy , C , Bundgaard , C , Mogg , A J , Thompson , K J , Dwomoh , L , Sanger , H E , Crabtree , M D , Brooke , S M , Sexton , P M , Felder , C C , Christopoulos , A , Broad , L M , Tobin , A B & Langmead , C J 2018 , ' Bitopic binding mode of an M 1 muscarinic acetylcholine receptor agonist associated with adverse clinical trial outcomes S ' , Molecular Pharmacology , vol. 93 , no. 6 , pp. 645-656 . https://doi.org/10.1124/mol.118.111872.  , 2018
 
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M1 muscarinic allosteric modulators slow prion neurodegener..:

Bradley, Sophie J ; Bourgognon, Julie Myrtille ; Sanger, Helen E...
Bradley , S J , Bourgognon , J M , Sanger , H E , Verity , N , Mogg , A J , White , D J , Butcher , A J , Moreno , J A , Molloy , C , Macedo-Hatch , T , Edwards , J M , Wess , J , Pawlak , R , Read , D J , Sexton , P M , Broad , L M , Steinert , J R , Mallucci , G R , Christopoulos , A , Felder , C C & Tobin , A B 2017 , ' M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss ' , The Journal of Clinical Investigation , vol. 127 , no. 2 , pp. 487-499 . https://doi.org/10.1172/JCI87526.  , 2017
 
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Activation of Muscarinic M1 Acetylcholine Receptors Induces..:

Dennis, Siobhan ; Pasqui, Francesca ; Colvin, Ellen M...
Dennis , S , Pasqui , F , Colvin , E M , Sanger , H , Mogg , A J , Felder , C C , Broad , L M , Fitzjohn , S , Isaac , J T R & Mellor , J 2016 , ' Activation of Muscarinic M1 Acetylcholine Receptors Induces Long-Term Potentiation in the Hippocampus ' , Cerebral Cortex , vol. 26 , no. 1 , pp. 414-426 . https://doi.org/10.1093/cercor/bhv227.  , 2016
 
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TRPV3 in Drug Development:

Broad, Lisa M ; Mogg, Adrian J ; Eberle, Elizabeth...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039508/.  , 2016
 
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