E-LIB Suche - Ergebnisse für: Appleby, Todd C.

1

Structural basis for substrate selection by the SARS-CoV-2 ..:

Malone, Brandon F. ; Perry, Jason K. ; Olinares, Paul Dominic B....
Nature. 614 (2023) 7949 - p. 781-787 , 2023

Link: https://doi.org/10.1038/..

2

Characterization of a KDM5 small molecule inhibitor with an..:

Gilmore, Sarah A. ; Tam, Danny ; Cheung, Tara L....
PLOS ONE. 17 (2022) 12 - p. e0271145 , 2022

Link: https://doi.org/10.1371/..

3

An atomistic model of the coronavirus replication-transcrip..:

Perry, Jason K. ; Appleby, Todd C. ; Bilello, John P....
Journal of Biological Chemistry. 297 (2021) 4 - p. 101218 , 2021

Link: https://doi.org/10.1016/..

4

Protein Footprinting and X-ray Crystallography Reveal the I..:

Niu, Ben ; Appleby, Todd C. ; Wang, Ruth...
Biochemistry. 59 (2019) 4 - p. 541-551 , 2019

Link: https://doi.org/10.1021/..

5

Discovery of a 2′-fluoro-2′- C -methyl C -nucleotide HCV po..:

Kirschberg, Thorsten A. ; Metobo, Sammy ; Clarke, Michael O....
Bioorganic & Medicinal Chemistry Letters. 27 (2017) 8 - p. 1840-1847 , 2017

Link: https://doi.org/10.1016/..

6

Biochemical characterization and structure determination of..:

Appleby, Todd C. ; Greenstein, Andrew E. ; Hung, Magdeleine...
Journal of Biological Chemistry. 292 (2017) 16 - p. 6810-6820 , 2017

Link: https://doi.org/10.1074/..

7

Discovery of Potent Cyclophilin Inhibitors Based on the Str..:

Steadman, Victoria A. ; Pettit, Simon B. ; Poullennec, Karine G....
Journal of Medicinal Chemistry. 60 (2017) 3 - p. 1000-1017 , 2017

Link: https://doi.org/10.1021/..

8

Structural basis for RNA replication by the hepatitis C vir..:

Appleby, Todd C. ; Perry, Jason K. ; Murakami, Eisuke...
Science. 347 (2015) 6223 - p. 771-775 , 2015

Link: https://doi.org/10.1126/..

9

Structural basis for RNA replication by the hepatitis C vir..:

Appleby, Todd C. ; Perry, Jason K. ; Murakami, Eisuke...
Science. 347 (2015) 6223 - p. 771-775 , 2015

Link: http://www.jstor.org/sta..

10

An adaptive mutation in NS2 is essential for efficient prod..:

Chan, Katie ; Cheng, Guofeng ; Beran, Rudolf K.F....
Virology. 422 (2012) 2 - p. 224-234 , 2012

Link: https://doi.org/10.1016/..

11

Visualizing ATP-Dependent RNA Translocation by the NS3 Heli..:

Appleby, Todd C. ; Anderson, Robert ; Fedorova, Olga...
Journal of Molecular Biology. 405 (2011) 5 - p. 1139-1153 , 2011

Link: https://doi.org/10.1016/..

12

Structure of human uridine-cytidine kinase 2 determined by ..:

Appleby, Todd C. ; Larson, Gary ; Cheney, I. Wayne...
Acta Crystallographica Section D Biological Crystallography. 61 (2005) 3 - p. 278-284 , 2005

Link: https://doi.org/10.1107/..

13

Hepatitis C Virus Therapies: Current Treatments, Targets an..:

Walker, Michelle P ; Appleby, Todd C ; Zhong, Weidong..
Antiviral Chemistry and Chemotherapy. 14 (2003) 1 - p. 1-21 , 2003

Link: https://doi.org/10.1177/..

14

Three-dimensional Structure of a Hyperthermophilic 5′-Deoxy..:

Appleby, Todd C. ; Mathews, Irimpan I. ; Porcelli, Marina..
Journal of Biological Chemistry. 276 (2001) 42 - p. 39232-39242 , 2001

Link: https://doi.org/10.1074/..

15

The structural basis for the remarkable catalytic proficien..:

Begley, Tadhg P ; Appleby, Todd C ; Ealick*, Steven E
Current Opinion in Structural Biology. 10 (2000) 6 - p. 711-718 , 2000

Link: https://doi.org/10.1016/..