E-LIB Suche - Ergebnisse für: Börjesson, Ulf

1

Fragment-Based Discovery of Novel MUS81 Inhibitors:

Collie, Gavin W. ; Börjesson, Ulf ; Chen, Yunhua...
ACS Medicinal Chemistry Letters. 15 (2024) 7 - p. 1151-1158 , 2024

2

Design of a Lead-Like Cysteine-Targeting Covalent Library a..:

Lucas, Simon C. C. ; Milbradt, Alexander G. ; Blackwell, J. Henry...
Journal of Medicinal Chemistry. 67 (2024) 13 - p. 11209-11225 , 2024

Link: https://doi.org/10.1021/..

3

Identification and Evaluation of Reversible Covalent Binder..:

Lucas, Simon C. C. ; Blackwell, J. Henry ; Börjesson, Ulf...
ACS Medicinal Chemistry Letters. 15 (2024) 6 - p. 791-797 , 2024

Link: https://doi.org/10.1021/..

4

Discovery and Optimization of the First ATP Competitive Typ..:

Michaelides, Iacovos N. ; Collie, Gavin W. ; Börjesson, Ulf...
Journal of Medicinal Chemistry. 66 (2023) 13 - p. 8782-8807 , 2023

Link: https://doi.org/10.1021/..

5

Chemogenetics defines a short-chain fatty acid receptor gut..:

Barki, Natasja ; Bolognini, Daniele ; Börjesson, Ulf...
eLife. 11 (2022) - p. , 2022

Link: https://doi.org/10.7554/..

6

Discovery of a selective c-MET inhibitor with a novel bindi..:

Collie, Gavin W. ; Barlind, Louise ; Bazzaz, Sana...
Bioorganic & Medicinal Chemistry Letters. 75 (2022) - p. 128948 , 2022

Link: https://doi.org/10.1016/..

7

Surprising lipophilicity observations identify unexpected c..:

Perry, Matthew W.D. ; Börjesson, Ulf ; Nikitidis, Antonios.
Bioorganic & Medicinal Chemistry Letters. 69 (2022) - p. 128786 , 2022

Link: https://doi.org/10.1016/..

8

Fragment screening at AstraZeneca: developing the next gene..:

Lucas, Simon C. C. ; Börjesson, Ulf ; Bostock, Mark J....
RSC Medicinal Chemistry. 13 (2022) 9 - p. 1052-1057 , 2022

Link: https://doi.org/10.1039/..

9

Fragment-Based Design of a Potent MAT2a Inhibitor and in Vi..:

De Fusco, Claudia ; Schimpl, Marianne ; Börjesson, Ulf...
Journal of Medicinal Chemistry. 64 (2021) 10 - p. 6814-6826 , 2021

Link: https://doi.org/10.1021/..

10

Fragment-Based Discovery of Novel Allosteric MEK1 Binders:

Di Fruscia, Paolo ; Edfeldt, Fredrik ; Shamovsky, Igor...
ACS Medicinal Chemistry Letters. 12 (2021) 2 - p. 302-308 , 2021

Link: https://doi.org/10.1021/..

11

Discovery of AZD8154, a Dual PI3Kγδ Inhibitor for the Treat..:

Perry, Matthew W. D. ; Björhall, Karin ; Bold, Peter...
Journal of Medicinal Chemistry. 64 (2021) 12 - p. 8053-8075 , 2021

Link: https://doi.org/10.1021/..

12

Structural Basis for Targeting the Folded P-Loop Conformati..:

Collie, Gavin W. ; Michaelides, Iacovos N. ; Embrey, Kevin...
ACS Medicinal Chemistry Letters. 12 (2020) 1 - p. 162-167 , 2020

Link: https://doi.org/10.1021/..

13

Phenotypic high-throughput screening platform identifies no..:

Brito, Hugo ; Marques, Vanda ; Afonso, Marta B....
Cell Death Discovery. 6 (2020) 1 - p. , 2020

Link: https://doi.org/10.1038/..

14

Industrial scale high-throughput screening delivers multipl..:

Clare, Rachel H. ; Bardelle, Catherine ; Harper, Paul...
Nature Communications. 10 (2019) 1 - p. , 2019

Link: https://doi.org/10.1038/..

15

ProSAR: A New Methodology for Combinatorial Library Design:

Chen, Hongming ; Börjesson, Ulf ; Engkvist, Ola...
Journal of Chemical Information and Modeling. 49 (2009) 3 - p. 603-614 , 2009

Link: https://doi.org/10.1021/..