E-LIB Suche - Ergebnisse für: Begley, Darren W.

1

Mycofactocin-associated mycobacterial dehydrogenases with n..:

Haft, Daniel H. ; Pierce, Phillip G. ; Mayclin, Stephen J....
Scientific Reports. 7 (2017) 1 - p. , 2017

Link: https://doi.org/10.1038/..

2

Increasing the structural coverage of tuberculosis drug tar..:

Baugh, Loren ; Phan, Isabelle ; Begley, Darren W....
Tuberculosis. 95 (2015) 2 - p. 142-148 , 2015

Link: https://doi.org/10.1016/..

3

Synthesis and biological evaluation of pyrazolopyrimidines ..:

Goshu, Gashaw M. ; Ghose, Debarati ; Bain, Joy M....
Bioorganic & Medicinal Chemistry Letters. 25 (2015) 24 - p. 5699-5704 , 2015

Link: https://doi.org/10.1016/..

4

Structural analysis of H1N1 and H7N9 influenza A virus PA i..:

Moen, Spencer O. ; Abendroth, Jan ; Fairman, James W....
Scientific Reports. 4 (2014) 1 - p. , 2014

Link: https://doi.org/10.1038/..

5

Multi-target Parallel Processing Approach for Gene-to-struc..

JoVE : Immunology and Infection

Armour, Brianna L. ; Barnes, Steve R. ; Moen, Spencer O.... , 2013

Link: https://www.jove.com/t/4..

6

Saturation Transfer Difference NMR for Fragment Screening:

Begley, Darren W. ; Moen, Spencer O. ; Pierce, Phillip G..
Current Protocols in Chemical Biology. 5 (2013) 2 - p. 251-268 , 2013

Link: https://doi.org/10.1002/..

7

Cytidine derivatives as IspF inhibitors of Burkolderia pseu..:

Zhang, Zheng ; Jakkaraju, Sriram ; Blain, Joy...
Bioorganic & Medicinal Chemistry Letters. 23 (2013) 24 - p. 6860-6863 , 2013

Link: https://doi.org/10.1016/..

8

Combining Functional and Structural Genomics to Sample the ..:

Baugh, Loren ; Gallagher, Larry A. ; Patrapuvich, Rapatbhorn...
PLoS ONE. 8 (2013) 1 - p. e53851 , 2013

Link: https://doi.org/10.1371/..

9

A Small-Molecule Probe Induces a Conformation in HIV TAR RN..:

Davidson, Amy ; Begley, Darren W. ; Lau, Carmen.
Journal of Molecular Biology. 410 (2011) 5 - p. 984-996 , 2011

Link: https://doi.org/10.1016/..

10

Probing conformational states of glutaryl-CoA dehydrogenase..:

Begley, Darren W. ; Davies, Douglas R. ; Hartley, Robert C....
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 67 (2011) 9 - p. 1060-1069 , 2011

Link: https://doi.org/10.1107/..

11

Inhibitor-bound complexes of dihydrofolate reductase-thymid..:

Begley, Darren W. ; Edwards, Thomas E. ; Raymond, Amy C....
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 67 (2011) 9 - p. 1070-1077 , 2011

Link: https://doi.org/10.1107/..

12

Structural genomics of infectious disease drug targets: the..:

Stacy, Robin ; Begley, Darren W. ; Phan, Isabelle...
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 67 (2011) 9 - p. 979-984 , 2011

Link: https://doi.org/10.1107/..

13

The Protein Maker: an automated system for high-throughput ..:

Smith, Eric R. ; Begley, Darren W. ; Anderson, Vanessa...
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 67 (2011) 9 - p. 1015-1021 , 2011

Link: https://doi.org/10.1107/..

14

Fragment‐based discovery of novel thymidylate synthase lead..:

Begley, Darren W. ; Zheng, Suxin ; Varani, Gabriele
Chemical Biology & Drug Design. 76 (2010) 3 - p. 218-233 , 2010

Link: https://doi.org/10.1111/..

15

Locking out viral replication:

Begley, Darren W ; Varani, Gabriele
Nature Chemical Biology. 5 (2009) 11 - p. 782-783 , 2009

Link: https://doi.org/10.1038/..