E-LIB Suche - Ergebnisse für: Blake, James F.

1

Discovery of 5-Azaquinoxaline Derivatives as Potent and Ora..:

Elsayed, Mohamed S. A. ; Blake, James F. ; Boys, Mark L....
ACS Medicinal Chemistry Letters. 14 (2023) 12 - p. 1673-1681 , 2023

Link: https://doi.org/10.1021/..

2

Identification of MRTX1133, a Noncovalent, Potent, and Sele..:

Wang, Xiaolun ; Allen, Shelley ; Blake, James F....
Journal of Medicinal Chemistry. 65 (2021) 4 - p. 3123-3133 , 2021

Link: https://doi.org/10.1021/..

3

Identification of the Clinical Development Candidate MRTX84..:

Fell, Jay B. ; Fischer, John P. ; Baer, Brian R....
Journal of Medicinal Chemistry. 63 (2020) 13 - p. 6679-6693 , 2020

Link: https://doi.org/10.1021/..

4

RET Solvent Front Mutations Mediate Acquired Resistance to ..:

Solomon, Benjamin J. ; Tan, Lavinia ; Lin, Jessica J....
Journal of Thoracic Oncology. 15 (2020) 4 - p. 541-549 , 2020

Link: https://doi.org/10.1016/..

5

Use of QSPR Modeling to Characterize In Vitro Binding of Dr..:

Brew, Christine Taylor ; Blake, James F. ; Mistry, Anita...
Pharmaceutical Research. 35 (2018) 4 - p. , 2018

Link: https://doi.org/10.1007/..

6

Discovery of Tetrahydropyridopyrimidines as Irreversible Co..:

Fell, Jay B. ; Fischer, John P. ; Baer, Brian R....
ACS Medicinal Chemistry Letters. 9 (2018) 12 - p. 1230-1234 , 2018

Link: https://doi.org/10.1021/..

7

Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyet..:

Blake, James F. ; Burkard, Michael ; Chan, Jocelyn...
Journal of Medicinal Chemistry. 59 (2016) 12 - p. 5650-5660 , 2016

Link: https://doi.org/10.1021/..

8

Discovery of Highly Potent, Selective, and Efficacious Smal..:

Ren, Li ; Grina, Jonas ; Moreno, David...
Journal of Medicinal Chemistry. 58 (2015) 4 - p. 1976-1991 , 2015

Link: https://doi.org/10.1021/..

9

Discovery of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine inhi..:

Blake, James F. ; Gaudino, John J. ; De Meese, Jason...
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 12 - p. 2635-2639 , 2014

Link: https://doi.org/10.1016/..

10

Discovery and Preclinical Pharmacology of a Selective ATP-C..:

Blake, James F. ; Xu, Rui ; Bencsik, Josef R....
Journal of Medicinal Chemistry. 55 (2012) 18 - p. 8110-8127 , 2012

Link: https://doi.org/10.1021/..

11

Discovery and SAR of spirochromane Akt inhibitors:

Kallan, Nicholas C. ; Spencer, Keith L. ; Blake, James F....
Bioorganic & Medicinal Chemistry Letters. 21 (2011) 8 - p. 2410-2414 , 2011

Link: https://doi.org/10.1016/..

12

Discovery of spirocyclic sulfonamides as potent Akt inhibit..:

Xu, Rui ; Banka, Anna ; Blake, James F....
Bioorganic & Medicinal Chemistry Letters. 21 (2011) 8 - p. 2335-2340 , 2011

Link: https://doi.org/10.1016/..

13

Discovery of dihydrothieno- and dihydrofuropyrimidines as p..:

Bencsik, Josef R. ; Xiao, Dengming ; Blake, James F....
Bioorganic & Medicinal Chemistry Letters. 20 (2010) 23 - p. 7037-7041 , 2010

Link: https://doi.org/10.1016/..

14

Discovery of pyrrolopyrimidine inhibitors of Akt:

Blake, James F. ; Kallan, Nicholas C. ; Xiao, Dengming...
Bioorganic & Medicinal Chemistry Letters. 20 (2010) 19 - p. 5607-5612 , 2010

Link: https://doi.org/10.1016/..

15

Non-nucleoside inhibitors of HCV NS5B polymerase. Part 1: S..:

Hendricks, Robert T. ; Fell, Jay B. ; Blake, James F....
Bioorganic & Medicinal Chemistry Letters. 19 (2009) 13 - p. 3637-3641 , 2009

Link: https://doi.org/10.1016/..