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Bowers, Simeon
26  Ergebnisse:
Personensuche X
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1

Required Immunoproteasome Subunit Inhibition Profile for An..:

Johnson, Henry W. B. ; Lowe, Eric ; Anderl, Janet L....
Journal of Medicinal Chemistry.  61 (2018)  24 - p. 11127-11143 , 2018
Link: https://doi.org/10.1021/..
 
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2

Antibody–Drug Conjugates (ADCs) Derived from Interchain Cys..:

Behrens, Christopher R. ; Ha, Edward H. ; Chinn, Lawrence L....
Molecular Pharmaceutics.  12 (2015)  11 - p. 3986-3998 , 2015
Link: https://doi.org/10.1021/..
 
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3

Discovery of (R)-4-Cyclopropyl-7,8-difluoro-5-(4-(trifluoro..:

Probst, Gary ; Aubele, Danielle L. ; Bowers, Simeon...
Journal of Medicinal Chemistry.  56 (2013)  13 - p. 5261-5274 , 2013
Link: https://doi.org/10.1021/..
 
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4

Novel cinnoline-based inhibitors of LRRK2 kinase activity:

Garofalo, Albert W. ; Adler, Marc ; Aubele, Danielle L....
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  1 - p. 71-74 , 2013
Link: https://doi.org/10.1016/..
 
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5

Design and synthesis of thiophene dihydroisoquinolines as n..:

Xu, Ying-zi ; Yuan, Shendong ; Bowers, Simeon...
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  10 - p. 3075-3080 , 2013
Link: https://doi.org/10.1016/..
 
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6

Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhi..:

Ng, Raymond A. ; Sun, Minghua ; Bowers, Simeon...
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  16 - p. 4674-4679 , 2013
Link: https://doi.org/10.1016/..
 
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7

Design and synthesis of highly selective, orally active Pol..:

Bowers, Simeon ; Truong, Anh P. ; Ye, Michael...
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  9 - p. 2743-2749 , 2013
Link: https://doi.org/10.1016/..
 
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8

Structure-based design of novel dihydroisoquinoline BACE-1 ..:

Bowers, Simeon ; Xu, Ying-zi ; Yuan, Shendong...
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  7 - p. 2181-2186 , 2013
Link: https://doi.org/10.1016/..
 
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9

Pharmacological inhibition of Polo Like Kinase 2 (PLK2) doe..:

Fitzgerald, Kent ; Bergeron, Marcelle ; Willits, Christopher...
Toxicology and Applied Pharmacology.  269 (2013)  1 - p. 1-7 , 2013
Link: https://doi.org/10.1016/..
 
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10

Selective and Brain‐Permeable Polo‐like Kinase‐2 (Plk‐2) In..:

Aubele, Danielle L. ; Hom, Roy K. ; Adler, Marc...
ChemMedChem.  8 (2013)  8 - p. 1295-1313 , 2013
Link: https://doi.org/10.1002/..
 
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11

Design, synthesis and structure–activity relationship of no..:

Aubele, Danielle L. ; Truong, Anh P. ; Dressen, Darren B....
Bioorganic & Medicinal Chemistry Letters.  21 (2011)  19 - p. 5791-5794 , 2011
Link: https://doi.org/10.1016/..
 
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12

Design and synthesis of a novel, orally active, brain penet..:

Bowers, Simeon ; Truong, Anh P. ; Neitz, R. Jeffrey...
Bioorganic & Medicinal Chemistry Letters.  21 (2011)  6 - p. 1838-1843 , 2011
Link: https://doi.org/10.1016/..
 
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13

Highly selective c-Jun N-terminal kinase (JNK) 2 and 3 inhi..:

Probst, Gary D. ; Bowers, Simeon ; Sealy, Jennifer M....
Bioorganic & Medicinal Chemistry Letters.  21 (2011)  1 - p. 315-319 , 2011
Link: https://doi.org/10.1016/..
 
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14

Design and synthesis of brain penetrant selective JNK inhib..:

Bowers, Simeon ; Truong, Anh P. ; Jeffrey Neitz, R....
Bioorganic & Medicinal Chemistry Letters.  21 (2011)  18 - p. 5521-5527 , 2011
Link: https://doi.org/10.1016/..
 
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15

Corrigendum to "Design, synthesis, and structure–activity r..:

Truong, Anh P. ; Aubele, Danielle L. ; Probst, Gary D....
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  24 - p. 7553 , 2010
Link: https://doi.org/10.1016/..
 
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