E-LIB Suche - Ergebnisse für: Brassil, Patrick

1

Lung-restricted ALK5 inhibition avoids systemic toxicities ..:

Maher, Jonathan M. ; Zhang, Rui ; Palanisamy, Gopinath...
Toxicology and Applied Pharmacology. 438 (2022) - p. 115905 , 2022

Link: https://doi.org/10.1016/..

2

Gut-Selective Design of Orally Administered Izencitinib (TD..:

Hardwick, Rhiannon N ; Brassil, Patrick ; Badagnani, Ilaria...
Toxicological Sciences. 186 (2022) 2 - p. 323-337 , 2022

Link: https://doi.org/10.1093/..

3

Heteroarylamide smoothened inhibitors: Discovery of N-[2,4-..:

Yang, Bin ; Hird, Alexander W. ; Bodnarchuk, Michael S....
Bioorganic & Medicinal Chemistry. 28 (2020) 2 - p. 115227 , 2020

Link: https://doi.org/10.1016/..

4

Development of Gut-Selective Pan-Janus Kinase Inhibitor TD-..:

Sandborn, William J ; Nguyen, Deanna D ; Beattie, David T...
Journal of Crohn's and Colitis. 14 (2020) 9 - p. 1202-1213 , 2020

Link: https://doi.org/10.1093/..

5

Adventures in Scaffold Morphing: Discovery of Fused Ring He..:

Yang, Bin ; Vasbinder, Melissa M. ; Hird, Alexander W....
Journal of Medicinal Chemistry. 61 (2018) 3 - p. 1061-1073 , 2018

Link: https://doi.org/10.1021/..

6

Intestinally-restricted Janus Kinase inhibition: a potentia..:

Beattie, David T. ; Pulido-Rios, M. Teresa ; Shen, Fei...
Journal of Inflammation. 14 (2017) 1 - p. , 2017

Link: https://doi.org/10.1186/..

7

Novel DNA Gyrase Inhibiting Spiropyrimidinetriones with a B..:

Basarab, Gregory S. ; Brassil, Patrick ; Doig, Peter...
Journal of Medicinal Chemistry. 57 (2014) 21 - p. 9078-9095 , 2014

Link: https://doi.org/10.1021/..

8

Structure activity relationship studies of 3-arylsulfonyl-p..:

Hu, Shuanghua ; Huang, Yazhong ; Wu, Yong-Jin...
Bioorganic & Medicinal Chemistry. 22 (2014) 5 - p. 1782-1790 , 2014

Link: https://doi.org/10.1016/..

9

A novel uHPLC–MS/MS method for the quantitation of AZD7451 ..:

Peer, Cody J. ; Brown, Jeffrey L. ; Martin, Timothy J....
Journal of Chromatography B. 942-943 (2013) - p. 107-112 , 2013

Link: https://doi.org/10.1016/..

10

Potent and Selective Inhibitors of CK2 Kinase Identified th..:

Dowling, James E. ; Chuaqui, Claudio ; Pontz, Timothy W....
ACS Medicinal Chemistry Letters. 3 (2012) 4 - p. 278-283 , 2012

Link: https://doi.org/10.1021/..

11

Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topo..:

Reck, Folkert ; Alm, Richard A. ; Brassil, Patrick...
Journal of Medicinal Chemistry. 55 (2012) 15 - p. 6916-6933 , 2012

Link: https://doi.org/10.1021/..

12

Discovery of Checkpoint Kinase Inhibitor (S)-5-(3-Fluorophe..:

Oza, Vibha ; Ashwell, Susan ; Almeida, Lynsie...
Journal of Medicinal Chemistry. 55 (2012) 11 - p. 5130-5142 , 2012

Link: https://doi.org/10.1021/..

13

Synthesis and evaluation of triazolones as checkpoint kinas..:

Oza, Vibha ; Ashwell, Susan ; Brassil, Patrick...
Bioorganic & Medicinal Chemistry Letters. 22 (2012) 6 - p. 2330-2337 , 2012

Link: https://doi.org/10.1016/..

14

Discovery of novel hedgehog antagonists from cell-based scr..:

Yang, Bin ; Hird, Alexander W. ; Russell, Daniel John...
Bioorganic & Medicinal Chemistry Letters. 22 (2012) 14 - p. 4907-4911 , 2012

Link: https://doi.org/10.1016/..

15

Discovery of (+)-N-(3-Aminopropyl)-N-[1-(5-benzyl-3-methyl-..:

Theoclitou, Maria-Elena ; Aquila, Brian ; Block, Michael H....
Journal of Medicinal Chemistry. 54 (2011) 19 - p. 6734-6750 , 2011

Link: https://doi.org/10.1021/..