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Brennan, Frank R.
4506  Ergebnisse:
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1

Beyond MABEL: An Integrative Approach to First in Human Dos..:

Matsumoto, Mineo ; Polli, Joseph Ryan ; Swaminathan, Suresh K....
Clinical Pharmacology & Therapeutics.  , 2024
Link: https://doi.org/10.1002/..
 
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2

Current nonclinical approaches for immune assessments of im..:

Grimaldi, Christine ; Ibraghimov, Alex ; Kiessling, Andrea...
Drug Discovery Today.  28 (2023)  2 - p. 103440 , 2023
Link: https://doi.org/10.1016/..
 
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3

Strategies and Recommendations for Using a Data‐Driven and ..:

Leach, Michael W. ; Clarke, David O. ; Dudal, Sherri...
Clinical Pharmacology & Therapeutics.  109 (2020)  6 - p. 1395-1416 , 2020
Link: https://doi.org/10.1002/..
 
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4

Monoclonal Antibodies for Immune System-Mediated Diseases:

, In: Nijkamp and Parnham's Principles of Immunopharmacology,
Brennan, Frank R. ; Smith, Emma ; Dudal, Sherri - p. 369-406 , 2019
Link: https://doi.org/10.1007/..
 
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5

Integration of Consortia Recommendations for Justification ..:

Prior, Helen ; Monticello, Thomas ; Boulifard, Virginie..
International Journal of Toxicology.  38 (2019)  4 - p. 319-325 , 2019
Link: https://doi.org/10.1177/..
 
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6

Generation of two high affinity anti-mouse FcRn antibodies:..:

Smith, Bryan ; Christodoulou, Louis ; Clargo, Alison...
International Immunopharmacology.  66 (2019)  - p. 362-365 , 2019
Link: https://doi.org/10.1016/..
 
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7

Engineered hexavalent Fc proteins with enhanced Fc-gamma re..:

Rowley, Tania F. ; Peters, Shirley J. ; Aylott, Mike...
Communications Biology.  1 (2018)  1 - p. , 2018
Link: https://doi.org/10.1038/..
 
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8

Current strategies in the non-clinical safety assessment of..:

Brennan, Frank R. ; Andrews, Laura ; Arulanandam, Antonio R....
Regulatory Toxicology and Pharmacology.  98 (2018)  - p. 98-107 , 2018
Link: https://doi.org/10.1016/..
 
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9

In vitro assays supporting the safety assessment of immunom..:

Brennan, Frank R. ; Kiessling, Andrea
Toxicology in Vitro.  45 (2017)  - p. 296-308 , 2017
Link: https://doi.org/10.1016/..
 
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10

Translational immunotoxicology of immunomodulatory monoclon..:

Brennan, Frank R. ; Kiessling, Andrea
Drug Discovery Today: Technologies.  21-22 (2016)  - p. 85-93 , 2016
Link: https://doi.org/10.1016/..
 
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11

Nonclinical safety testing of biopharmaceuticals – Addressi..:

Brennan, Frank R. ; Baumann, Andreas ; Blaich, Guenter...
Regulatory Toxicology and Pharmacology.  73 (2015)  1 - p. 265-275 , 2015
Link: https://doi.org/10.1016/..
 
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12

MAbs Targeting Soluble Mediators in Phase 1 and 2 Clinical ..:

, In: Handbook of Therapeutic Antibodies,
Brennan, Frank R. - p. 969-1078 , 2014
Link: https://doi.org/10.1002/..
 
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13

mAbs Targeting Apoptosis, Angiogenesis Inhibitors, and Othe..:

, In: Handbook of Therapeutic Antibodies,
Brennan, Frank R. - p. 1175-1194 , 2014
Link: https://doi.org/10.1002/..
 
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14

Inhibitors of Leukocyte Adhesion and Migration in Phase 1 a..:

, In: Handbook of Therapeutic Antibodies,
Brennan, Frank R. - p. 1127-1144 , 2014
Link: https://doi.org/10.1002/..
 
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15

Optimized Nonclinical Safety Assessment Strategies Supporti..:

Brennan, Frank R. ; Cauvin, Annick ; Tibbitts, Jay.
Drug Development Research.  75 (2014)  3 - p. 115-161 , 2014
Link: https://doi.org/10.1002/..
 
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