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X
Butcher, John W.
1480  Ergebnisse:
Personensuche X
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1

Discovery of MK-8318, a Potent and Selective CRTh2 Receptor..:

Huang, Xianhai ; Brubaker, Jason ; Zhou, Wei...
ACS Medicinal Chemistry Letters.  9 (2018)  7 - p. 679-684 , 2018
Link: https://doi.org/10.1021/..
 
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2

Overcoming Mutagenicity and Ion Channel Activity: Optimizat..:

Ellis, J. Michael ; Altman, Michael D. ; Bass, Alan...
Journal of Medicinal Chemistry.  58 (2015)  4 - p. 1929-1939 , 2015
Link: https://doi.org/10.1021/..
 
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3

P2‐Quinazolinones and Bis‐Macrocycles as New Templates for ..:

Rudd, Michael T. ; Butcher, John W. ; Nguyen, Kevin T....
ChemMedChem.  10 (2015)  4 - p. 727-735 , 2015
Link: https://doi.org/10.1002/..
 
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4

Development of potent macrocyclic inhibitors of genotype 3a..:

Rudd, Michael T. ; McCauley, John A. ; Romano, Joseph J....
Bioorganic & Medicinal Chemistry Letters.  22 (2012)  23 - p. 7201-7206 , 2012
Link: https://doi.org/10.1016/..
 
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5

Development of macrocyclic inhibitors of HCV NS3/4A proteas..:

Rudd, Michael T. ; McIntyre, Charles J. ; Romano, Joseph J....
Bioorganic & Medicinal Chemistry Letters.  22 (2012)  23 - p. 7207-7213 , 2012
Link: https://doi.org/10.1016/..
 
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6

Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4..:

Harper, Steven ; McCauley, John A. ; Rudd, Michael T....
ACS Medicinal Chemistry Letters.  3 (2012)  4 - p. 332-336 , 2012
Link: https://doi.org/10.1021/..
 
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7

Discovery ofMK-1220: A Macrocyclic Inhibitor of Hepatitis C..:

Rudd, Michael T. ; McCauley, John A. ; Butcher, John W....
ACS Medicinal Chemistry Letters.  2 (2011)  3 - p. 207-212 , 2011
Link: https://doi.org/10.1021/..
 
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8

Discovery of Vaniprevir (MK-7009), a Macrocyclic Hepatitis ..:

McCauley, John A. ; McIntyre, Charles J. ; Rudd, Michael T....
Journal of Medicinal Chemistry.  53 (2010)  6 - p. 2443-2463 , 2010
Link: https://doi.org/10.1021/..
 
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9

Synthesis and evaluation of novel tricyclic benzo[4.5]cyclo..:

McIntyre, Charles J. ; McCauley, John A. ; Bednar, Bohumil...
Bioorganic & Medicinal Chemistry Letters.  19 (2009)  17 - p. 5132-5135 , 2009
Link: https://doi.org/10.1016/..
 
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10

Molecular Modeling Based Approach to Potent P2−P4 Macrocycl..:

Liverton, Nigel J. ; Holloway, M. Katharine ; McCauley, John A....
Journal of the American Chemical Society.  130 (2008)  14 - p. 4607-4609 , 2008
Link: https://doi.org/10.1021/..
 
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11

Identification and Characterization of 4-Methylbenzyl 4-[(P..:

Liverton, Nigel J. ; Bednar, Rodney A. ; Bednar, Bohumil...
Journal of Medicinal Chemistry.  50 (2007)  4 - p. 807-819 , 2007
Link: https://doi.org/10.1021/..
 
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12

Synthesis of the first sulfur-35-labeled hERG radioligand:

Raab, Conrad E. ; Butcher, John W. ; Connolly, Thomas M....
Bioorganic & Medicinal Chemistry Letters.  16 (2006)  6 - p. 1692-1695 , 2006
Link: https://doi.org/10.1016/..
 
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13

Novel 5-cyclopropyl-1,4-benzodiazepin-2-ones as potent and ..:

Butcher, John W ; Liverton, Nigel J ; Claremon, David A...
Bioorganic & Medicinal Chemistry Letters.  13 (2003)  6 - p. 1165-1168 , 2003
Link: https://doi.org/10.1016/..
 
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14

A new series of potent benzodiazepine γ-secretase inhibitor:

Churcher, Ian ; Ashton, Kate ; Butcher, John W....
Bioorganic & Medicinal Chemistry Letters.  13 (2003)  2 - p. 179-183 , 2003
Link: https://doi.org/10.1016/..
 
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15

Corrigendum to 'Novel 5-Cyclopropyl-1,4-benzodiazepine-2-on..:

Butcher, John W ; Liverton, Nigel J ; Claremon, David A...
Bioorganic & Medicinal Chemistry Letters.  13 (2003)  15 - p. 2611 , 2003
Link: https://doi.org/10.1016/..
 
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