E-LIB Suche - Ergebnisse für: Charisse, Klaus

1

Targeted siRNA lipid nanoparticles for the treatment of KRA..:

Anthiya, Shubaash ; Öztürk, Süleyman Can ; Yanik, Hamdullah...
Journal of Controlled Release. 357 (2023) - p. 67-83 , 2023

Link: https://doi.org/10.1016/..

2

Metabolically Stable Anomeric Linkages Containing GalNAc–si..:

Kandasamy, Pachamuthu ; Mori, Shohei ; Matsuda, Shigeo...
Journal of Medicinal Chemistry. 66 (2023) 4 - p. 2506-2523 , 2023

Link: https://doi.org/10.1021/..

3

Shorter Is Better: The α-(l)-Threofuranosyl Nucleic Acid Mo..:

Matsuda, Shigeo ; Bala, Saikat ; Liao, Jen-Yu...
Journal of the American Chemical Society. 145 (2023) 36 - p. 19691-19706 , 2023

Link: https://doi.org/10.1021/..

4

From bench to bedside: Improving the clinical safety of Gal..:

Schlegel, Mark K ; Janas, Maja M ; Jiang, Yongfeng...
Nucleic Acids Research. 50 (2022) 12 - p. 6656-6670 , 2022

Link: https://doi.org/10.1093/..

5

Role of a "Magic" Methyl: 2′-Deoxy-2′-α-F-2′-β-C-methyl Pyr..:

Guenther, Dale C. ; Mori, Shohei ; Matsuda, Shigeo...
Journal of the American Chemical Society. 144 (2022) 32 - p. 14517-14534 , 2022

Link: https://doi.org/10.1021/..

6

Chirality matters: stereo-defined phosphorothioate linkages..:

Jahns, Hartmut ; Taneja, Nate ; Willoughby, Jennifer L S...
Nucleic Acids Research. 50 (2021) 3 - p. 1221-1240 , 2021

Link: https://doi.org/10.1093/..

7

Overcoming GNA/RNA base-pairing limitations using isonucleo..:

Schlegel, Mark K ; Matsuda, Shigeo ; Brown, Christopher R...
Nucleic Acids Research. 49 (2021) 19 - p. 10851-10867 , 2021

Link: https://doi.org/10.1093/..

8

Investigational RNAi Therapeutic Targeting C5 Is Efficaciou..:

Kusner, Linda L. ; Yucius, Kristina ; Sengupta, Manjistha...
Molecular Therapy - Methods & Clinical Development. 13 (2019) - p. 484-492 , 2019

Link: https://doi.org/10.1016/..

9

5′-Morpholino modification of the sense strand of an siRNA ..:

Kumar, Pawan ; Parmar, Rubina G. ; Brown, Christopher R....
Chemical Communications. 55 (2019) 35 - p. 5139-5142 , 2019

Link: https://doi.org/10.1039/..

10

Safety evaluation of 2′-deoxy-2′-fluoro nucleotides in GalN..:

Janas, Maja M ; Zlatev, Ivan ; Liu, Ju...
Nucleic Acids Research. 47 (2019) 7 - p. 3306-3320 , 2019

Link: https://doi.org/10.1093/..

11

Structural basis for the synergy of 4′- and 2′-modification..:

Harp, Joel M ; Guenther, Dale C ; Bisbe, Anna...
Nucleic Acids Research. 46 (2018) 16 - p. 8090-8104 , 2018

Link: https://doi.org/10.1093/..

12

Facile Synthesis, Geometry, and 2′-Substituent-Dependent in..:

Parmar, Rubina Giare ; Brown, Christopher R. ; Matsuda, Shigeo...
Journal of Medicinal Chemistry. 61 (2018) 3 - p. 734-744 , 2018

Link: https://doi.org/10.1021/..

13

An efficient deprotection method for 5′-[O,O-bis(pivaloylox..:

O'Shea, Jonathan ; Theile, Christopher S. ; Das, Rajat...
Tetrahedron. 74 (2018) 42 - p. 6182-6186 , 2018

Link: https://doi.org/10.1016/..

14

Evaluation of GalNAc-siRNA Conjugate Activity in Pre-clinic..:

Willoughby, Jennifer L.S. ; Chan, Amy ; Sehgal, Alfica...
Molecular Therapy. 26 (2018) 1 - p. 105-114 , 2018

Link: https://doi.org/10.1016/..

15

Impact of enhanced metabolic stability on pharmacokinetics ..:

Nair, Jayaprakash K. ; Attarwala, Husain ; Sehgal, Alfica...
Nucleic Acids Research. 45 (2017) 19 - p. 10969-10977 , 2017

Link: https://doi.org/10.1093/..