E-LIB Suche - Ergebnisse für: Choo, Edna F.

1

Discovery of Spiro-azaindoline Inhibitors of Hematopoietic ..:

Chan, Bryan K. ; Seward, Eileen ; Lainchbury, Michael...
ACS Medicinal Chemistry Letters. 13 (2021) 1 - p. 84-91 , 2021

Link: https://doi.org/10.1021/..

2

Preclinical Safety Assessment of a Highly Selective and Pot..:

Katavolos, Paula ; Cain, Gary ; Farman, Cindy...
Toxicologic Pathology. 48 (2020) 3 - p. 465-480 , 2020

Link: https://doi.org/10.1177/..

3

Discovery of A-1331852, a First-in-Class, Potent, and Orall..:

Wang, Le ; Doherty, George A. ; Judd, Andrew S....
ACS Medicinal Chemistry Letters. 11 (2020) 10 - p. 1829-1836 , 2020

Link: https://doi.org/10.1021/..

4

Discovery of Potent Benzolactam IRAK4 Inhibitors with Robus..:

Rajapaksa, Naomi S. ; Gobbi, Alberto ; Drobnick, Joy...
ACS Medicinal Chemistry Letters. 11 (2019) 3 - p. 327-333 , 2019

Link: https://doi.org/10.1021/..

5

Development of Potent and Selective Pyrazolopyrimidine IRAK..:

Bryan, Marian C. ; Drobnick, Joy ; Gobbi, Alberto...
Journal of Medicinal Chemistry. 62 (2019) 13 - p. 6223-6240 , 2019

Link: https://doi.org/10.1021/..

6

Design and synthesis of a biaryl series as inhibitors for t..:

Lai, Kwong Wah ; Romero, F. Anthony ; Tsui, Vickie...
Bioorganic & Medicinal Chemistry Letters. 28 (2018) 1 - p. 15-23 , 2018

Link: https://doi.org/10.1016/..

7

Assessment of OATP transporter‐mediated drug–drug interacti..:

Chen, Yuan ; Zhu, Rui ; Ma, Fang...
Biopharmaceutics & Drug Disposition. 39 (2018) 9 - p. 420-430 , 2018

Link: https://doi.org/10.1002/..

8

Identification and profiling of GDC-0810 metabolites from a..:

Zhang, Chenghong ; Zhang, Donglu ; Choo, Edna F....
Drug Metabolism and Pharmacokinetics. 32 (2017) 1 - p. S76 , 2017

Link: https://doi.org/10.1016/..

9

Utility of CYP3A4 and PXR-CAR-CYP3A4/3A7 Transgenic Mouse M..:

Ly, Justin Q. ; Messick, Kirsten ; Qin, Ann..
Molecular Pharmaceutics. 14 (2017) 5 - p. 1754-1759 , 2017

Link: https://doi.org/10.1021/..

10

Leveraging Humanized Animal Models to Understand Human Drug..:

Choo, Edna F. ; Salphati, Laurent
Clinical Pharmacology & Therapeutics. 103 (2017) 2 - p. 188-192 , 2017

Link: https://doi.org/10.1002/..

11

GNE-781, A Highly Advanced Potent and Selective Bromodomain..:

Romero, F. Anthony ; Murray, Jeremy ; Lai, Kwong Wah...
Journal of Medicinal Chemistry. 60 (2017) 22 - p. 9162-9183 , 2017

Link: https://doi.org/10.1021/..

12

A Unique Approach to Design Potent and Selective Cyclic Ade..:

Bronner, Sarah M. ; Murray, Jeremy ; Romero, F. Anthony...
Journal of Medicinal Chemistry. 60 (2017) 24 - p. 10151-10171 , 2017

Link: https://doi.org/10.1021/..

13

Discovery of a Potent and Selective in Vivo Probe (GNE-272)..:

Crawford, Terry D. ; Romero, F. Anthony ; Lai, Kwong Wah...
Journal of Medicinal Chemistry. 59 (2016) 23 - p. 10549-10563 , 2016

Link: https://doi.org/10.1021/..

14

Structure based design of novel 6,5 heterobicyclic mitogen-..:

Robarge, Kirk D. ; Lee, Wendy ; Eigenbrot, Charles...
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 19 - p. 4714-4723 , 2014

Link: https://doi.org/10.1016/..

15

Structure-Guided Rescaffolding of Selective Antagonists of ..:

Koehler, Michael F. T. ; Bergeron, Philippe ; Choo, Edna F....
ACS Medicinal Chemistry Letters. 5 (2014) 6 - p. 662-667 , 2014

Link: https://doi.org/10.1021/..