E-LIB Suche - Ergebnisse für: Clader, John W.

1

Scaffold-hopping from xanthines to tricyclic guanines: A ca..:

Pissarnitski, Dmitri A. ; Zhao, Zhiqiang ; Cole, David...
Bioorganic & Medicinal Chemistry. 24 (2016) 21 - p. 5534-5545 , 2016

Link: https://doi.org/10.1016/..

2

Substituted 4-morpholine N -arylsulfonamides as γ-secretase..:

Zhao, Zhiqiang ; Pissarnitski, Dmitri A. ; Josien, Hubert B....
European Journal of Medicinal Chemistry. 124 (2016) - p. 36-48 , 2016

Link: https://doi.org/10.1016/..

3

Discovery of a Novel, Potent Spirocyclic Series of γ-Secret..:

Zhao, Zhiqiang ; Pissarnitski, Dmitri A. ; Josien, Hubert B....
Journal of Medicinal Chemistry. 58 (2015) 22 - p. 8806-8817 , 2015

Link: https://doi.org/10.1021/..

4

In Vivo Characterization of a Novel -Secretase Inhibitor SC..:

Hyde, Lynn A. ; Zhang, Qi ; Del Vecchio, Robert A....
International Journal of Alzheimer's Disease. 2013 (2013) - p. 1-14 , 2013

Link: https://doi.org/10.1155/..

5

Synthesis and SAR study of tricyclic sulfones as γ-secretas..:

Su, Jing ; Tang, Haiqun ; McKittrick, Brian A....
Bioorganic & Medicinal Chemistry Letters. 21 (2011) 11 - p. 3447-3451 , 2011

Link: https://doi.org/10.1016/..

6

Design, synthesis, and structure–activity relationship stud..:

Li, Hongmei ; Xu, Ruo ; Cole, David...
Bioorganic & Medicinal Chemistry Letters. 20 (2010) 22 - p. 6606-6609 , 2010

Link: https://doi.org/10.1016/..

7

Novel orally active morpholine N-arylsulfonamides γ-secreta..:

Josien, Hubert ; Bara, Thomas ; Rajagopalan, Murali...
Bioorganic & Medicinal Chemistry Letters. 19 (2009) 21 - p. 6032-6037 , 2009

Link: https://doi.org/10.1016/..

8

Discovery of amide and heteroaryl isosteres as carbamate re..:

McBriar, Mark D. ; Clader, John W. ; Chu, Inhou...
Bioorganic & Medicinal Chemistry Letters. 18 (2008) 1 - p. 215-219 , 2008

Link: https://doi.org/10.1016/..

9

Solution-Phase Parallel Synthesis of Carbamates as γ-Secret..:

Vaccaro, Henry A. ; Zhao, Zhiqiang ; Clader, John W....
Journal of Combinatorial Chemistry. 10 (2008) 1 - p. 56-62 , 2008

Link: https://doi.org/10.1021/..

10

Discovery of γ-secretase inhibitors efficacious in a transg..:

Asberom, Theodros ; Zhao, Zhiqiang ; Bara, Thomas A....
Bioorganic & Medicinal Chemistry Letters. 17 (2007) 2 - p. 511-516 , 2007

Link: https://doi.org/10.1016/..

11

SAR study of bicyclo[4.1.0]heptanes as melanin-concentratin..:

Su, Jing ; McKittrick, Brian A. ; Tang, Haiqun...
Bioorganic & Medicinal Chemistry. 15 (2007) 16 - p. 5369-5385 , 2007

Link: https://doi.org/10.1016/..

12

Tetrahydroquinoline sulfonamides as γ-secretase inhibitors:

Asberom, Theodros ; Bara, Thomas A. ; Clader, John W....
Bioorganic & Medicinal Chemistry Letters. 17 (2007) 1 - p. 205-207 , 2007

Link: https://doi.org/10.1016/..

13

Discovery of 2,4,6-trisubstituted N-arylsulfonyl piperidine..:

Li, Hongmei ; Asberom, Theodros ; Bara, Thomas A....
Bioorganic & Medicinal Chemistry Letters. 17 (2007) 22 - p. 6290-6294 , 2007

Link: https://doi.org/10.1016/..

14

Synthesis of novel bicyclo[4.1.0]heptane and bicyclo[3.1.0]..:

Su, Jing ; Tang, Haiqun ; McKittrick, Brian A....
Bioorganic & Medicinal Chemistry Letters. 17 (2007) 17 - p. 4845-4850 , 2007

Link: https://doi.org/10.1016/..

15

2,6-Disubstituted N-arylsulfonyl piperidines as γ-secretase..:

Pissarnitski, Dmitri A. ; Asberom, Theodros ; Bara, Thomas A....
Bioorganic & Medicinal Chemistry Letters. 17 (2007) 1 - p. 57-62 , 2007

Link: https://doi.org/10.1016/..