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Dar, Arvin C.
458  Ergebnisse:
Personensuche X
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1

The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Po..:

Ryan, Meagan B. ; Quade, Bradley ; Schenk, Natasha...
Cancer Discovery.  , 2024
Link: https://doi.org/10.1158/..
 
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2

Live-cell target engagement of allosteric MEKi on MEK–RAF/K..:

Marsiglia, William M. ; Chow, Arthur ; Khan, Zaigham M...
Nature Chemical Biology.  20 (2023)  3 - p. 373-381 , 2023
Link: https://doi.org/10.1038/..
 
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3

Targeting drug-resistant mutations in ALK:

He, Liu ; Dar, Arvin C.
Nature Cancer.  3 (2022)  6 - p. 659-661 , 2022
Link: https://doi.org/10.1038/..
 
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4

RASopathy mutations open new insights into the mechanism of..:

Dar, Arvin C. ; Brady, Donita C.
Molecular Cell.  82 (2022)  22 - p. 4192-4193 , 2022
Link: https://doi.org/10.1016/..
 
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5

Understanding and drugging RAS: 40 years to break the tip o..:

Brady, Donita C. ; Hmeljak, Julija ; Dar, Arvin C.
Disease Models & Mechanisms.  15 (2022)  2 - p. , 2022
Link: https://doi.org/10.1242/..
 
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6

An Antagonist of KSR1‐Driven Adaptive Resistance to Clinica..:

Chow, Arthur ; Yerabolu, Jayasudhan R. ; Reyes, Kyna..
The FASEB Journal.  36 (2022)  S1 - p. , 2022
Link: https://doi.org/10.1096/..
 
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7

Type II Binders Targeting the "GLR-Out" Conformation of the..:

Smith, Ryan H. B. ; Khan, Zaigham M. ; Ung, Peter Man-Un...
Biochemistry.  60 (2021)  4 - p. 289-302 , 2021
Link: https://doi.org/10.1021/..
 
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8

Structural basis for the action of the drug trametinib at K..:

Khan, Zaigham M. ; Real, Alexander M. ; Marsiglia, William M....
Nature.  588 (2020)  7838 - p. 509-514 , 2020
Link: https://doi.org/10.1038/..
 
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9

Integrated computational and Drosophila cancer model platfo..:

Ung, Peter M. U. ; Sonoshita, Masahiro ; Scopton, Alex P....
PLOS Computational Biology.  15 (2019)  4 - p. e1006878 , 2019
Link: https://doi.org/10.1371/..
 
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10

Small molecule stabilization of the KSR inactive state anta..:

Dhawan, Neil S. ; Scopton, Alex P. ; Dar, Arvin C.
Nature.  537 (2016)  7618 - p. 112-116 , 2016
Link: https://doi.org/10.1038/..
 
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11

2. Hepatitis C Virus Can Evolve Resistance To microRNA-122 ..:

Mullokandov, Gavriel ; Israelow, Benjamin ; Agudo, Judith...
Molecular Therapy.  23 (2015)  - p. S1 , 2015
Link: https://doi.org/10.1016/..
 
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12

Endoplasmic reticulum stress-independent activation of unfo..:

Mendez, Aaron S ; Alfaro, Jennifer ; Morales-Soto, Marisol A...
eLife.  4 (2015)  - p. , 2015
Link: https://doi.org/10.7554/..
 
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13

CNS Anticancer Drug Discovery and Development Conference Wh..:

Levin, Victor A. ; Tonge, Peter J. ; Gallo, James M....
Neuro-Oncology.  17 (2015)  suppl 6 - p. vi1-vi26 , 2015
Link: https://doi.org/10.1093/..
 
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14

Structure-Guided Inhibitor Design Expands the Scope of Anal..:

Zhang, Chao ; Lopez, Michael S. ; Dar, Arvin C....
ACS Chemical Biology.  8 (2013)  9 - p. 1931-1938 , 2013
Link: https://doi.org/10.1021/..
 
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15

Chemical genetic discovery of targets and anti-targets for ..:

Dar, Arvin C. ; Das, Tirtha K. ; Shokat, Kevan M..
Nature.  486 (2012)  7401 - p. 80-84 , 2012
Link: https://doi.org/10.1038/..
 
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