E-LIB Suche - Ergebnisse für: DeGoey, David A.

1

Beyond Rule of Five and PROTACs in Modern Drug Discovery: P..:

Price, Edward ; Weinheimer, Manuel ; Rivkin, Alexey...
Journal of Medicinal Chemistry. 67 (2024) 7 - p. 5683-5698 , 2024

Link: https://doi.org/10.1021/..

2

Discovery of (R)-(3-fluoropyrrolidin-1-yl)(6-((5-(trifluoro..:

Patel, Meena V. ; Peltier, Hillary M. ; Matulenko, Mark A....
Bioorganic & Medicinal Chemistry. 63 (2022) - p. 116743 , 2022

Link: https://doi.org/10.1016/..

3

Antiviral Drug Discovery for the Treatment of COVID-19 Infe..:

Ng, Teresa I. ; Correia, Ivan ; Seagal, Jane...
Viruses. 14 (2022) 5 - p. 961 , 2022

Link: https://doi.org/10.3390/..

4

Implications of the Conformationally Flexible, Macrocyclic ..:

Sheikh, Ahmad Y. ; Mattei, Alessandra ; Miglani Bhardwaj, Rajni...
Journal of the American Chemical Society. 143 (2021) 42 - p. 17479-17491 , 2021

Link: https://doi.org/10.1021/..

5

Desymmetrization of pibrentasvir for efficient prodrug synt..:

Voight, Eric A. ; Greszler, Stephen N. ; Hartung, John...
Chemical Science. 12 (2021) 29 - p. 10076-10082 , 2021

Link: https://doi.org/10.1039/..

6

Global Analysis of Models for Predicting Human Absorption: ..:

Price, Edward ; Kalvass, J. Cory ; DeGoey, David...
Journal of Medicinal Chemistry. 64 (2021) 13 - p. 9389-9403 , 2021

Link: https://doi.org/10.1021/..

7

Prodrug Strategies to Improve the Solubility of the HCV NS5..:

Randolph, John T. ; Voight, Eric A. ; Greszler, Stephen N....
Journal of Medicinal Chemistry. 63 (2020) 19 - p. 11034-11044 , 2020

Link: https://doi.org/10.1021/..

8

Synthesis and evaluation of 2′-dihalo ribonucleotide prodru..:

Chris Krueger, A. ; Chen, Hui-Ju ; Randolph, John T....
Bioorganic & Medicinal Chemistry. 28 (2020) 1 - p. 115208 , 2020

Link: https://doi.org/10.1016/..

9

Discovery of 2-aminoisobutyric acid ethyl ester (AIBEE) pho..:

Randolph, John T. ; Li, Tongmei ; Chris Krueger, A....
Bioorganic & Medicinal Chemistry Letters. 30 (2020) 7 - p. 126986 , 2020

Link: https://doi.org/10.1016/..

10

HCV NS5A as an Antiviral Therapeutic Target: From Validatio..:

, In: Topics in Medicinal Chemistry; HCV: The Journey from Discovery to a Cure,

Wagner, Rolf ; DeGoey, David A. ; Randolph, John T.... - p. 133-156 , 2019

Link: https://doi.org/10.1007/..

11

Beyond the Rule of 5: Lessons Learned from AbbVie's Drugs a..:

DeGoey, David A. ; Chen, Hui-Ju ; Cox, Philip B..
Journal of Medicinal Chemistry. 61 (2017) 7 - p. 2636-2651 , 2017

Link: https://doi.org/10.1021/..

12

Substituted Indazoles as Nav1.7 Blockers for the Treatment ..:

Frost, Jennifer M. ; DeGoey, David A. ; Shi, Lei...
Journal of Medicinal Chemistry. 59 (2016) 7 - p. 3373-3391 , 2016

Link: https://doi.org/10.1021/..

13

LPA1 Receptor Antagonists Exhibit Signaling Bias and Differ..:

Hazelwood, Lisa A ; Leys, Laura ; Lundgaard, Greta...
The FASEB Journal. 30 (2016) S1 - p. , 2016

Link: https://doi.org/10.1096/..

14

Discovery of ABT-267, a Pan-Genotypic Inhibitor of HCV NS5A:

DeGoey, David A. ; Randolph, John T. ; Liu, Dachun...
Journal of Medicinal Chemistry. 57 (2014) 5 - p. 2047-2057 , 2014

Link: https://doi.org/10.1021/..

15

Discovery of pyrido[2,3-d]pyrimidine-based inhibitors of HC..:

DeGoey, David A. ; Betebenner, David A. ; Grampovnik, David J....
Bioorganic & Medicinal Chemistry Letters. 23 (2013) 12 - p. 3627-3630 , 2013

Link: https://doi.org/10.1016/..