E-LIB Suche - Ergebnisse für: Eric Vangrevelinghe

1

Discovery of Potent, Orally Bioavailable, Tricyclic NLRP3 I..:

Velcicky, Juraj ; Janser, Philipp ; Gommermann, Nina...
Journal of Medicinal Chemistry. 67 (2024) 2 - p. 1544-1562 , 2024

Link: https://doi.org/10.1021/..

2

NIBR-LTSi is a selective LATS kinase inhibitor activating Y..:

Namoto, Kenji ; Baader, Clara ; Orsini, Vanessa...
Cell Stem Cell. 31 (2024) 4 - p. 554-569.e17 , 2024

Link: https://doi.org/10.1016/..

3

Novel Concept for Super-Soft Topical Drugs: Deactivation by..:

Thoma, Gebhard ; Vangrevelinghe, Eric ; Luneau, Alexandre...
ACS Medicinal Chemistry Letters. 14 (2023) 6 - p. 841-845 , 2023

Link: https://doi.org/10.1021/..

4

Design of a Supersoft Topical JAK Inhibitor, Which Is Effec..:

Thoma, Gebhard ; Decoret, Odile ; Vangrevelinghe, Eric...
Journal of Medicinal Chemistry. 66 (2023) 21 - p. 15042-15053 , 2023

Link: https://doi.org/10.1021/..

5

Structure-Based Optimization of a Fragment-like TLR8 Bindin..:

Betschart, Claudia ; Faller, Michael ; Zink, Florence...
ACS Medicinal Chemistry Letters. 13 (2022) 4 - p. 658-664 , 2022

Link: https://doi.org/10.1021/..

6

Target-Based Identification and Optimization of 5-Indazol-5..:

Knoepfel, Thomas ; Nimsgern, Pierre ; Jacquier, Sébastien...
Journal of Medicinal Chemistry. 63 (2020) 15 - p. 8276-8295 , 2020

Link: https://doi.org/10.1021/..

7

Discovery and Structural Characterization of ATP-Site Ligan..:

McNally, Randall ; Li, Qing ; Li, Kunhua...
ACS Chemical Biology. 14 (2019) 4 - p. 587-593 , 2019

Link: https://doi.org/10.1021/..

8

Identification and characterization of a phenyl-thiazolyl-b..:

Koshiishi, Chie ; Kanazawa, Takanori ; Vangrevelinghe, Eric..
Heliyon. 5 (2019) 11 - p. e02849 , 2019

Link: https://doi.org/10.1016/..

9

Optimizing a Weakly Binding Fragment into a Potent RORγt In..:

Carcache, David A. ; Vulpetti, Anna ; Kallen, Joerg...
Journal of Medicinal Chemistry. 61 (2018) 15 - p. 6724-6735 , 2018

Link: https://doi.org/10.1021/..

10

An Activating Janus Kinase-3 Mutation Is Associated with Cy..:

Sic, Heiko ; Speletas, Matthaios ; Cornacchione, Vanessa...
Frontiers in Immunology. 8 (2017) - p. , 2017

Link: https://doi.org/10.3389/..

11

Indolyl-naphthyl-maleimides as potent and selective inhibit..:

van Eis, Maurice J. ; Evenou, JeanPierre ; Schuler, Walter...
Bioorganic & Medicinal Chemistry Letters. 27 (2017) 4 - p. 781-786 , 2017

Link: https://doi.org/10.1016/..

12

Discovery and Profiling of a Selective and Efficacious Syk ..:

Thoma, Gebhard ; Smith, Alexander B. ; van Eis, Maurice J....
Journal of Medicinal Chemistry. 58 (2015) 4 - p. 1950-1963 , 2015

Link: https://doi.org/10.1021/..

13

Orally bioavailable Syk inhibitors with activity in a rat P..:

Thoma, Gebhard ; Veenstra, Siem ; Strang, Ross...
Bioorganic & Medicinal Chemistry Letters. 25 (2015) 20 - p. 4642-4647 , 2015

Link: https://doi.org/10.1016/..

14

Syk inhibitors with high potency in presence of blood:

Thoma, Gebhard ; Blanz, Joachim ; Bühlmayer, Peter...
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 10 - p. 2278-2282 , 2014

Link: https://doi.org/10.1016/..

15

Novel ROCK inhibitors for the treatment of pulmonary arteri..:

Shaw, Duncan ; Hollingworth, Greg ; Soldermann, Nicolas...
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 20 - p. 4812-4817 , 2014

Link: https://doi.org/10.1016/..