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X
Fraley, Mark E.
221  Ergebnisse:
Personensuche X
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1

Pharmacologic characterization of atogepant: A potent and s..:

Moore, Eric ; Bell, Ian M ; Fraley, Mark E...
Cephalalgia.  44 (2024)  1 - p. , 2024
Link: https://doi.org/10.1177/..
 
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2

Pyrazole Ureas as Low Dose, CNS Penetrant Glucosylceramide ..:

Roecker, Anthony J. ; Schirripa, Kathy M. ; Loughran, H. Marie...
ACS Medicinal Chemistry Letters.  14 (2023)  2 - p. 146-155 , 2023
Link: https://doi.org/10.1021/..
 
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3

Fluorinated Isoindolinone-Based Glucosylceramide Synthase I..:

Loughran, H. Marie ; Schirripa, Kathy M. ; Roecker, Anthony J....
ACS Medicinal Chemistry Letters.  15 (2023)  1 - p. 123-131 , 2023
Link: https://doi.org/10.1021/..
 
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4

Novel oxazolidinone calcitonin gene-related peptide (CGRP) ..:

Crowley, Brendan M. ; Stump, Craig A. ; Nguyen, Diem N....
Bioorganic & Medicinal Chemistry Letters.  25 (2015)  21 - p. 4777-4781 , 2015
Link: https://doi.org/10.1016/..
 
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5

Adenosine analogue inhibitors of S-adenosylhomocysteine hyd..:

Converso, Antonella ; Hartingh, Timothy ; Fraley, Mark E....
Bioorganic & Medicinal Chemistry Letters.  24 (2014)  12 - p. 2737-2740 , 2014
Link: https://doi.org/10.1016/..
 
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6

Cover Picture: Discovery of 5′′‐Chloro‐N‐[(5,6‐dimethoxypyr..:

Roecker, Anthony J. ; Mercer, Swati P. ; Schreier, John D....
ChemMedChem.  9 (2014)  2 - p. 241-241 , 2014
Link: https://doi.org/10.1002/..
 
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7

Discovery of 5′′‐Chloro‐N‐[(5,6‐dimethoxypyridin‐2‐yl)methy..:

Roecker, Anthony J. ; Mercer, Swati P. ; Schreier, John D....
ChemMedChem.  9 (2013)  2 - p. 311-322 , 2013
Link: https://doi.org/10.1002/..
 
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8

Pyridyl aminothiazoles as potent Chk1 inhibitors: Optimizat..:

Dudkin, Vadim Y. ; Wang, Cheng ; Arrington, Kenneth L....
Bioorganic & Medicinal Chemistry Letters.  22 (2012)  7 - p. 2613-2619 , 2012
Link: https://doi.org/10.1016/..
 
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9

Pyridyl aminothiazoles as potent inhibitors of Chk1 with sl..:

Dudkin, Vadim Y. ; Rickert, Keith ; Kreatsoulas, Constantine...
Bioorganic & Medicinal Chemistry Letters.  22 (2012)  7 - p. 2609-2612 , 2012
Link: https://doi.org/10.1016/..
 
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10

3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive al..:

Brnardic, Edward J. ; Fraley, Mark E. ; Garbaccio, Robert M....
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  10 - p. 3129-3133 , 2010
Link: https://doi.org/10.1016/..
 
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11

Stereospecific reduction of a potent kinesin spindle protei..:

Li, Chunze ; Lu, Bing ; Garbaccio, Robert M....
Biochemical Pharmacology.  79 (2010)  10 - p. 1526-1533 , 2010
Link: https://doi.org/10.1016/..
 
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12

Discovery of Oxazolobenzimidazoles as Positive Allosteric M..:

Garbaccio, Robert M. ; Brnardic, Edward J. ; Fraley, Mark E....
ACS Medicinal Chemistry Letters.  1 (2010)  8 - p. 406-410 , 2010
Link: https://doi.org/10.1021/..
 
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13

Development of thioquinazolinones, allosteric Chk1 kinase i..:

Converso, Antonella ; Hartingh, Timothy ; Garbaccio, Robert M....
Bioorganic & Medicinal Chemistry Letters.  19 (2009)  4 - p. 1240-1244 , 2009
Link: https://doi.org/10.1016/..
 
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14

Kinesin Spindle Protein (KSP) Inhibitors. 9. Discovery of (..:

Cox, Christopher D. ; Coleman, Paul J. ; Breslin, Michael J....
Journal of Medicinal Chemistry.  51 (2008)  14 - p. 4239-4252 , 2008
Link: https://doi.org/10.1021/..
 
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15

Synthesis and evaluation of substituted benzoisoquinolinone..:

Garbaccio, Robert M. ; Huang, Shaei ; Tasber, Edward S....
Bioorganic & Medicinal Chemistry Letters.  17 (2007)  22 - p. 6280-6285 , 2007
Link: https://doi.org/10.1016/..
 
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