E-LIB Suche - Ergebnisse für: Gehling, Victor S.

1

Identification and characterization of second-generation EZ..:

Stuckey, Jacob I. ; Cantone, Nico R. ; Côté, Alexandre...
Journal of Biological Chemistry. 296 (2021) - p. 100349 , 2021

Link: https://doi.org/10.1016/..

2

Design and Synthesis of Styrenylcyclopropylamine LSD1 Inhib..:

Gehling, Victor S. ; McGrath, John P. ; Duplessis, Martin...
ACS Medicinal Chemistry Letters. 11 (2020) 6 - p. 1213-1220 , 2020

Link: https://doi.org/10.1021/..

3

Design, Synthesis, and Pharmacological Evaluation of Second..:

Khanna, Avinash ; Côté, Alexandre ; Arora, Shilpi...
ACS Medicinal Chemistry Letters. 11 (2020) 6 - p. 1205-1212 , 2020

Link: https://doi.org/10.1021/..

4

From a novel HTS hit to potent, selective, and orally bioav..:

Liang, Jun ; Labadie, Sharada ; Zhang, Birong...
Bioorganic & Medicinal Chemistry Letters. 27 (2017) 13 - p. 2974-2981 , 2017

Link: https://doi.org/10.1016/..

5

Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihy..:

Vaswani, Rishi G. ; Gehling, Victor S. ; Dakin, Les A....
Journal of Medicinal Chemistry. 59 (2016) 21 - p. 9928-9941 , 2016

Link: https://doi.org/10.1021/..

6

Identification of a Benzoisoxazoloazepine Inhibitor (CPI-06..:

Albrecht, Brian K. ; Gehling, Victor S. ; Hewitt, Michael C....
Journal of Medicinal Chemistry. 59 (2016) 4 - p. 1330-1339 , 2016

Link: https://doi.org/10.1021/..

7

Identification of potent, selective KDM5 inhibitors:

Gehling, Victor S. ; Bellon, Steven F. ; Harmange, Jean-Christophe...
Bioorganic & Medicinal Chemistry Letters. 26 (2016) 17 - p. 4350-4354 , 2016

Link: https://doi.org/10.1016/..

8

Lead optimization of a pyrazolo[1,5-a]pyrimidin-7(4H)-one s..:

Liang, Jun ; Zhang, Birong ; Labadie, Sharada...
Bioorganic & Medicinal Chemistry Letters. 26 (2016) 16 - p. 4036-4041 , 2016

Link: https://doi.org/10.1016/..

9

Corrigendum to "Development of methyl isoxazoleazepines as ..:

Hewitt, Michael C. ; Leblanc, Yves ; Gehling, Victor S....
Bioorganic & Medicinal Chemistry Letters. 25 (2015) 17 - p. 3755 , 2015

Link: https://doi.org/10.1016/..

10

Discovery, design, and synthesis of indole-based EZH2 inhib..:

Gehling, Victor S. ; Vaswani, Rishi G. ; Nasveschuk, Christopher G....
Bioorganic & Medicinal Chemistry Letters. 25 (2015) 17 - p. 3644-3649 , 2015

Link: https://doi.org/10.1016/..

11

Development of methyl isoxazoleazepines as inhibitors of BE:

Hewitt, Michael C. ; Leblanc, Yves ; Gehling, Victor S....
Bioorganic & Medicinal Chemistry Letters. 25 (2015) 9 - p. 1842-1848 , 2015

Link: https://doi.org/10.1016/..

12

Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally ..:

Taylor, Alexander M. ; Vaswani, Rishi G. ; Gehling, Victor S....
ACS Medicinal Chemistry Letters. 7 (2015) 2 - p. 145-150 , 2015

Link: https://doi.org/10.1021/..

13

A Practical Synthesis of Indoles via a Pd-Catalyzed C–N Rin..:

Vaswani, Rishi G. ; Albrecht, Brian K. ; Audia, James E....
Organic Letters. 16 (2014) 16 - p. 4114-4117 , 2014

Link: https://doi.org/10.1021/..

14

EZH2 Inhibitor Efficacy in Non-Hodgkin's Lymphoma Does Not ..:

Bradley, William D. ; Arora, Shilpi ; Busby, Jennifer...
Chemistry & Biology. 21 (2014) 11 - p. 1463-1475 , 2014

Link: https://doi.org/10.1016/..

15

Discovery, Design, and Optimization of Isoxazole Azepine BE..:

Gehling, Victor S. ; Hewitt, Michael C. ; Vaswani, Rishi G....
ACS Medicinal Chemistry Letters. 4 (2013) 9 - p. 835-840 , 2013

Link: https://doi.org/10.1021/..