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X
Gordon, Laurie
561  Ergebnisse:
Personensuche X
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1

Structure- and Property-Based Optimization of Efficient Pan..:

Hirst, David J. ; Bamborough, Paul ; Al-Mahdi, Niam...
Journal of Medicinal Chemistry.  67 (2024)  12 - p. 10464-10489 , 2024
Link: https://doi.org/10.1021/..
 
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2

Development of an intracellular quantitative assay to measu..:

Lay, Charles S. ; Thomas, Daniel A. ; Evans, John P....
Cell Chemical Biology.  30 (2023)  12 - p. 1692 , 2023
Link: https://doi.org/10.1016/..
 
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3

Identification and Optimization of a Ligand-Efficient Benzo..:

Humphreys, Philip G. ; Anderson, Niall A. ; Bamborough, Paul...
Journal of Medicinal Chemistry.  65 (2022)  22 - p. 15174-15207 , 2022
Link: https://doi.org/10.1021/..
 
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4

Development of an intracellular quantitative assay to measu..:

Lay, Charles S. ; Thomas, Daniel A. ; Evans, John P....
Cell Chemical Biology.  29 (2022)  2 - p. 287-299.e8 , 2022
Link: https://doi.org/10.1016/..
 
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5

Design, Synthesis, and Characterization of I-BET567, a Pan-..:

Humphreys, Philip G. ; Atkinson, Stephen J. ; Bamborough, Paul...
Journal of Medicinal Chemistry.  65 (2022)  3 - p. 2262-2287 , 2022
Link: https://doi.org/10.1021/..
 
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6

Optimization of a Series of 2,3-Dihydrobenzofurans as Highl..:

Lucas, Simon C. C. ; Atkinson, Stephen J. ; Chung, Chun-wa...
Journal of Medicinal Chemistry.  64 (2021)  15 - p. 10711-10741 , 2021
Link: https://doi.org/10.1021/..
 
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7

Fragment-based Scaffold Hopping: Identification of Potent, ..:

Seal, Jonathan T. ; Atkinson, Stephen J. ; Bamborough, Paul...
Journal of Medicinal Chemistry.  64 (2021)  15 - p. 10772-10805 , 2021
Link: https://doi.org/10.1021/..
 
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8

Optimization of a Series of RIPK2 PROTACs:

Miah, Afjal H. ; Smith, Ian E. D. ; Rackham, Mark...
Journal of Medicinal Chemistry.  64 (2021)  17 - p. 12978-13003 , 2021
Link: https://doi.org/10.1021/..
 
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9

Optimization of Naphthyridones into Selective TATA-Binding ..:

Clegg, Michael A. ; Theodoulou, Natalie H. ; Bamborough, Paul...
ACS Medicinal Chemistry Letters.  12 (2021)  8 - p. 1308-1317 , 2021
Link: https://doi.org/10.1021/..
 
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10

Discovery of a Novel Bromodomain and Extra Terminal Domain ..:

Jones, Katherine L. ; Beaumont, Dominic M. ; Bernard, Sharon G....
Journal of Medicinal Chemistry.  64 (2021)  16 - p. 12200-12227 , 2021
Link: https://doi.org/10.1021/..
 
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11

Template-Hopping Approach Leads to Potent, Selective, and H..:

Aylott, Helen E. ; Atkinson, Stephen J. ; Bamborough, Paul...
Journal of Medicinal Chemistry.  64 (2021)  6 - p. 3249-3281 , 2021
Link: https://doi.org/10.1021/..
 
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12

The Optimization of a Novel, Weak Bromo and Extra Terminal ..:

Seal, Jonathan T. ; Atkinson, Stephen J. ; Aylott, Helen...
Journal of Medicinal Chemistry.  63 (2020)  17 - p. 9093-9126 , 2020
Link: https://doi.org/10.1021/..
 
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13

Cellular Target Engagement Approaches to Monitor Epigenetic..:

Phillipou, Alexander N. ; Lay, Charles S. ; Carver, Charlotte E....
SLAS Discovery.  25 (2020)  2 - p. 163-175 , 2020
Link: https://doi.org/10.1177/..
 
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14

GSK789: A Selective Inhibitor of the First Bromodomains (BD..:

Watson, Robert J. ; Bamborough, Paul ; Barnett, Heather...
Journal of Medicinal Chemistry.  63 (2020)  17 - p. 9045-9069 , 2020
Link: https://doi.org/10.1021/..
 
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15

Design and Synthesis of a Highly Selective and In Vivo-Capa..:

Preston, Alex ; Atkinson, Stephen ; Bamborough, Paul...
Journal of Medicinal Chemistry.  63 (2020)  17 - p. 9070-9092 , 2020
Link: https://doi.org/10.1021/..
 
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