E-LIB Suche - Ergebnisse für: Groombridge, Sam

1

Identification and optimisation of a pyrimidopyridone serie..:

Cumming, Iain A. ; Degorce, Sébastien L. ; Aagaard, Anna...
Bioorganic & Medicinal Chemistry. 63 (2022) - p. 116729 , 2022

Link: https://doi.org/10.1016/..

2

Tricyclic Indazoles—A Novel Class of Selective Estrogen Rec..:

Scott, James S. ; Bailey, Andrew ; Buttar, David...
Journal of Medicinal Chemistry. 62 (2019) 3 - p. 1593-1608 , 2019

Link: https://doi.org/10.1021/..

3

Optimization of permeability in a series of pyrrolotriazine..:

Degorce, Sébastien L. ; Anjum, Rana ; Dillman, Keith S....
Bioorganic & Medicinal Chemistry. 26 (2018) 4 - p. 913-924 , 2018

Link: https://doi.org/10.1016/..

4

Discovery and Optimization of Pyrrolopyrimidine Inhibitors ..:

Scott, James S. ; Degorce, Sébastien L. ; Anjum, Rana...
Journal of Medicinal Chemistry. 60 (2017) 24 - p. 10071-10091 , 2017

Link: https://doi.org/10.1021/..

5

The acute glucose lowering effect of specific GPR120 activa..:

Sundström, Linda ; Myhre, Susanna ; Sundqvist, Monika...
PLOS ONE. 12 (2017) 12 - p. e0189060 , 2017

Link: https://doi.org/10.1371/..

6

Synthesis of novel, functionalised tricycles utilising the ..:

Boyd, Scott ; Davies, Robert D.M. ; Degorce, Sébastien L....
Tetrahedron Letters. 57 (2016) 1 - p. 152-154 , 2016

Link: https://doi.org/10.1016/..

7

Regioselectiveorthoalkylation of nitro indole, carbazole, b..:

Lamont, Scott G. ; Donald, Craig S. ; Lyman Feron, J..
Tetrahedron Letters. 56 (2015) 52 - p. 7165-7167 , 2015

Link: https://doi.org/10.1016/..

8

Structure-Based Design of Potent and Selective Inhibitors o..:

Boyd, Scott ; Brookfield, Joanna L. ; Critchlow, Susan E....
Journal of Medicinal Chemistry. 58 (2015) 8 - p. 3611-3625 , 2015

Link: https://doi.org/10.1021/..

9

Discovery of a series of 2-(pyridinyl)pyrimidines as potent..:

Waring, Michael J. ; Baker, David J. ; Bennett, Stuart N. L....
MedChemComm. 6 (2015) 6 - p. 1024-1029 , 2015

Link: https://doi.org/10.1039/..

10

Optimization of Brain Penetrant 11β-Hydroxysteroid Dehydrog..:

Goldberg, Frederick W. ; Dossetter, Alexander G. ; Scott, James S....
Journal of Medicinal Chemistry. 57 (2014) 3 - p. 970-986 , 2014

Link: https://doi.org/10.1021/..

11

Optimisation of aqueous solubility in a series of G protein..:

Scott, James S. ; Birch, Alan M. ; Brocklehurst, Katy J....
MedChemComm. 4 (2013) 1 - p. 95-100 , 2013

Link: https://doi.org/10.1039/..

12

Conformational restriction in a series of GPR119 agonists: ..:

Scott, James S. ; Brocklehurst, Katy J. ; Brown, Hayley S....
Bioorganic & Medicinal Chemistry Letters. 23 (2013) 11 - p. 3175-3179 , 2013

Link: https://doi.org/10.1016/..

13

Discovery and optimization of efficacious neutral 4-amino-6..:

Goldberg, Frederick W. ; Birch, Alan M. ; Leach, Andrew G....
MedChemComm. 4 (2013) 1 - p. 165-174 , 2013

Link: https://doi.org/10.1039/..

14

Property based optimisation of glucokinase activators – dis..:

Waring, Michael J. ; Clarke, David S. ; Fenwick, Mark D....
MedChemComm. 3 (2012) 9 - p. 1077 , 2012

Link: https://doi.org/10.1039/..

15

Use of Small-Molecule Crystal Structures To Address Solubil..:

Scott, James S. ; Birch, Alan M. ; Brocklehurst, Katy J....
Journal of Medicinal Chemistry. 55 (2012) 11 - p. 5361-5379 , 2012

Link: https://doi.org/10.1021/..