E-LIB Suche - Ergebnisse für: Harcken, Christian

1

Discovery of a Series of Pyrazinone RORγ Antagonists and Id..:

Harcken, Christian ; Csengery, Johanna ; Turner, Michael...
ACS Medicinal Chemistry Letters. 12 (2021) 1 - p. 143-154 , 2021

Link: https://doi.org/10.1021/..

2

Safety, pharmacokinetics and pharmacodynamics of BI 705564,..:

Litzenburger, Tobias ; Steffgen, Jürgen ; Benediktus, Ewald...
British Journal of Clinical Pharmacology. 87 (2020) 4 - p. 1824-1838 , 2020

Link: https://doi.org/10.1111/..

3

RORγt inhibition selectively targets IL-17 producing iNKT a..:

Venken, Koen ; Jacques, Peggy ; Mortier, Céline...
Nature Communications. 10 (2019) 1 - p. , 2019

Link: https://doi.org/10.1038/..

4

Discovery and optimization of pyrazole amides as antagonist..:

Harcken, Christian ; Sarko, Christopher ; Mao, Can...
Bioorganic & Medicinal Chemistry Letters. 29 (2019) 3 - p. 435-440 , 2019

Link: https://doi.org/10.1016/..

5

Identification of novel azaindazole CCR1 antagonist clinica..:

Harcken, Christian ; Kuzmich, Daniel ; Cook, Brain...
Bioorganic & Medicinal Chemistry Letters. 29 (2019) 3 - p. 441-448 , 2019

Link: https://doi.org/10.1016/..

6

An RORγt Oral Inhibitor Modulates IL-17 Responses in Periph..:

Bassolas-Molina, Helena ; Raymond, Ernest ; Labadia, Mark...
Frontiers in Immunology. 9 (2018) - p. , 2018

Link: https://doi.org/10.3389/..

7

BTK inhibition ameliorates kidney disease in spontaneous lu..:

Chalmers, Samantha A. ; Glynn, Elizabeth ; Garcia, Sayra J....
Clinical Immunology. 197 (2018) - p. 205-218 , 2018

Link: https://doi.org/10.1016/..

8

Selective glucocorticoid receptor modulation inhibits cytok..:

Bartko, Johann ; Derhaschnig, Ulla ; Neels, Tania...
Pharmacological Research. 125 (2017) - p. 215-223 , 2017

Link: https://doi.org/10.1016/..

9

Late-stage optimization of a tercyclic class of S1P 3 -spar..:

Horan, Joshua C. ; Kuzmich, Daniel ; Liu, Pingrong...
Bioorganic & Medicinal Chemistry Letters. 26 (2016) 2 - p. 466-471 , 2016

Link: https://doi.org/10.1016/..

10

Therapeutic Blockade of Immune Complex-Mediated Glomerulone..:

Chalmers, Samantha A. ; Doerner, Jessica ; Bosanac, Todd...
Scientific Reports. 6 (2016) 1 - p. , 2016

Link: https://doi.org/10.1038/..

11

CCR1 Plays a Critical Role in Modulating Pain through Hemat..:

Lewis, Nuruddeen D. ; Muthukumarana, Akalushi ; Fogal, Steven E....
PLoS ONE. 9 (2014) 8 - p. e105883 , 2014

Link: https://doi.org/10.1371/..

12

Identification of Highly Efficacious Glucocorticoid Recepto..:

Harcken, Christian ; Riether, Doris ; Kuzmich, Daniel...
Journal of Medicinal Chemistry. 57 (2014) 4 - p. 1583-1598 , 2014

Link: https://doi.org/10.1021/..

13

Development of an Enantioselective Hydrogenation Route to (..:

Reeves, Jonathan T. ; Tan, Zhulin ; Reeves, Diana C....
Organic Process Research & Development. 18 (2014) 7 - p. 904-911 , 2014

Link: https://doi.org/10.1021/..

14

Discovery of a potent and dissociated non-steroidal glucoco..:

Razavi, Hossein ; Riether, Doris ; Harcken, Christian...
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 8 - p. 1934-1940 , 2014

Link: https://doi.org/10.1016/..

15

Optimization of Drug-Like Properties of Nonsteroidal Glucoc..:

Harcken, Christian ; Riether, Doris ; Liu, Pingrong...
ACS Medicinal Chemistry Letters. 5 (2014) 12 - p. 1318-1323 , 2014

Link: https://doi.org/10.1021/..