E-LIB Suche - Ergebnisse für: Hargrove, Tatyana Y.

1

CYP51: A Major Drug Target in the Cytochrome P450 Superfami..:

Lepesheva, Galina I. ; Hargrove, Tatyana Y. ; Kleshchenko, Yuliya...
Lipids. 43 (2008) 12 - p. 1117-1125 , 2008

2

CYP51: A Major Drug Target in the Cytochrome P450 Superfami..:

Lepesheva, Galina I ; Hargrove, Tatyana Y ; Kleshchenko, Yuliya...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715142. , 2008

Link: http://www.ncbi.nlm.nih...

3

Identification of Potent and Selective Inhibitors of Acanth..:

Hargrove, Tatiana Y. ; Lamb, David C. ; Wawrzak, Zdzislaw...
Journal of Medicinal Chemistry. 67 (2024) 9 - p. 7443-7457 , 2024

Link: https://doi.org/10.1021/..

4

Oxygen‐18 Labeling Reveals a Mixed Fe−O Mechanism in the La..:

McCarty, Kevin D. ; Tateishi, Yasuhiro ; Hargrove, Tatiana Y...
Angewandte Chemie International Edition. 63 (2024) 9 - p. , 2024

Link: https://doi.org/10.1002/..

5

Oxygen‐18 Labeling Reveals a Mixed Fe−O Mechanism in the La..:

McCarty, Kevin D. ; Tateishi, Yasuhiro ; Hargrove, Tatiana Y...
Angewandte Chemie. 136 (2024) 9 - p. , 2024

Link: https://doi.org/10.1002/..

6

Processive kinetics in the three-step lanosterol 14α-demeth..:

McCarty, Kevin D. ; Sullivan, Molly E. ; Tateishi, Yasuhiro...
Journal of Biological Chemistry. 299 (2023) 7 - p. 104841 , 2023

Link: https://doi.org/10.1016/..

7

Unravelling the role of transient redox partner complexes i..:

Hargrove, Tatiana Y. ; Lamb, David C. ; Smith, Jarrod A....
Scientific Reports. 12 (2022) 1 - p. , 2022

Link: https://doi.org/10.1038/..

8

Relaxed Substrate Requirements of Sterol 14α-Demethylase fr..:

Hargrove, Tatiana Y. ; Wawrzak, Zdzislaw ; Rachakonda, Girish...
Journal of Medicinal Chemistry. 64 (2021) 23 - p. 17511-17522 , 2021

Link: https://doi.org/10.1021/..

9

Concerning P450 Evolution: Structural Analyses Support Bact..:

Lamb, David C ; Hargrove, Tatiana Y ; Zhao, Bin...
Molecular Biology and Evolution. 38 (2020) 3 - p. 952-967 , 2020

Link: https://doi.org/10.1093/..

10

A requirement for an active proton delivery network support..:

Hargrove, Tatiana Y. ; Wawrzak, Zdzislaw ; Guengerich, F. Peter.
Journal of Biological Chemistry. 295 (2020) 29 - p. 9998-10007 , 2020

Link: https://doi.org/10.1074/..

11

Validation of Human Sterol 14α-Demethylase (CYP51) Druggabi..:

Friggeri, Laura ; Hargrove, Tatiana Y. ; Wawrzak, Zdzislaw..
Journal of Medicinal Chemistry. 62 (2019) 22 - p. 10391-10401 , 2019

Link: https://doi.org/10.1021/..

12

Sterol 14α-Demethylase Structure-Based Optimization of Drug..:

Friggeri, Laura ; Hargrove, Tatiana Y. ; Rachakonda, Girish...
Journal of Medicinal Chemistry. 61 (2018) 23 - p. 10910-10921 , 2018

Link: https://doi.org/10.1021/..

13

Sterol 14α-Demethylase Structure-Based Design of VNI ((R)-N..:

Friggeri, Laura ; Hargrove, Tatiana Y. ; Wawrzak, Zdzislaw...
Journal of Medicinal Chemistry. 61 (2018) 13 - p. 5679-5691 , 2018

Link: https://doi.org/10.1021/..

14

Binding of a physiological substrate causes large-scale con..:

Hargrove, Tatiana Y. ; Wawrzak, Zdzislaw ; Fisher, Paxtyn M....
Journal of Biological Chemistry. 293 (2018) 50 - p. 19344-19353 , 2018

Link: https://doi.org/10.1074/..

15

Structural analyses of Candida albicans sterol 14α-demethyl..:

Hargrove, Tatiana Y. ; Friggeri, Laura ; Wawrzak, Zdzislaw...
Journal of Biological Chemistry. 292 (2017) 16 - p. 6728-6743 , 2017

Link: https://doi.org/10.1074/..