E-LIB Suche - Ergebnisse für: Hintermann, Samuel

1

Ligandability Assessment of IL-1β by Integrated Hit Identif..:

Vulpetti, Anna ; Rondeau, Jean-Michel ; Bellance, Marie-Hélène...
Journal of Medicinal Chemistry. 67 (2024) 10 - p. 8141-8160 , 2024

Link: https://doi.org/10.1021/..

2

Quantitative and functional characterisation of extracellul..:

Tréton, Gwenola ; Sayer, Claudia ; Schürz, Melanie...
Journal of Controlled Release. 361 (2023) - p. 694-716 , 2023

Link: https://doi.org/10.1016/..

3

Discovery, X-ray structure and CPP-conjugation enabled upta..:

Schneider, Anselm F. L. ; Kallen, Joerg ; Ottl, Johannes...
RSC Chemical Biology. 2 (2021) 6 - p. 1661-1668 , 2021

Link: https://doi.org/10.1039/..

4

Evolution of Novartis' Small Molecule Screening Deck Design:

Schuffenhauer, Ansgar ; Schneider, Nadine ; Hintermann, Samuel...
Journal of Medicinal Chemistry. 63 (2020) 23 - p. 14425-14447 , 2020

Link: https://doi.org/10.1021/..

5

Antagonizing Retinoic Acid-Related-Orphan Receptor Gamma Ac..:

Ecoeur, Florence ; Weiss, Jessica ; Kaupmann, Klemens...
Frontiers in Immunology. 10 (2019) - p. , 2019

Link: https://doi.org/10.3389/..

6

Structure-Based and Property-Driven Optimization of N-Aryl ..:

Hoegenauer, Klemens ; Kallen, Joerg ; Jiménez-Núñez, Eloísa...
Journal of Medicinal Chemistry. 62 (2019) 23 - p. 10816-10832 , 2019

Link: https://doi.org/10.1021/..

7

Optimizing a Weakly Binding Fragment into a Potent RORγt In..:

Carcache, David A. ; Vulpetti, Anna ; Kallen, Joerg...
Journal of Medicinal Chemistry. 61 (2018) 15 - p. 6724-6735 , 2018

Link: https://doi.org/10.1021/..

8

Pharmacological inhibition of RORγt suppresses the Th17 pat..:

Guendisch, Ulf ; Weiss, Jessica ; Ecoeur, Florence...
PLOS ONE. 12 (2017) 11 - p. e0188391 , 2017

Link: https://doi.org/10.1371/..

9

Structural States of RORγt: X‐ray Elucidation of Molecular ..:

Kallen, Joerg ; Izaac, Aude ; Be, Celine...
ChemMedChem. 12 (2017) 13 - p. 1014-1021 , 2017

Link: https://doi.org/10.1002/..

10

Synthesis and Biological Evaluation of New Triazolo‐ and Im..:

Hintermann, Samuel ; Guntermann, Christine ; Mattes, Henri...
ChemMedChem. 11 (2016) 24 - p. 2640-2648 , 2016

Link: https://doi.org/10.1002/..

11

Compound Property Optimization in Drug Discovery Using Quan..:

Chen, Xiaohui ; Hatsis, Panos ; Judge, Joyce...
Analytical Chemistry. 88 (2016) 23 - p. 11813-11820 , 2016

Link: https://doi.org/10.1021/..

12

Discovery of 1 H -pyrazolo[3,4- b ]pyridines as potent dual..:

Behnke, Dirk ; Cotesta, Simona ; Hintermann, Samuel...
Bioorganic & Medicinal Chemistry Letters. 25 (2015) 23 - p. 5555-5560 , 2015

Link: https://doi.org/10.1016/..

13

Synthesis of Orthogonally Protected 2,6-Diazaspiro[3.5]nona..:

Pudelko, Maciej ; Orain, David ; Hintermann, Samuel..
Synlett. 26 (2015) 13 - p. 1815-1818 , 2015

Link: https://doi.org/10.1055/..

14

Effects of Isoxazolo-Pyridinone 7e, a Potent Activator of t..:

Montarolo, Francesca ; Raffaele, Chiara ; Perga, Simona...
PLoS ONE. 9 (2014) 9 - p. e108791 , 2014

Link: https://doi.org/10.1371/..

15

Kinetic properties of "dual" orexin receptor antagonists at..:

Callander, Gabrielle E. ; Olorunda, Morenike ; Monna, Dominique...
Frontiers in Neuroscience. 7 (2013) - p. , 2013

Link: https://doi.org/10.3389/..