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Hussain, Ishrut
46  Ergebnisse:
Personensuche X
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1

Substrate determinants in the C99 juxtamembrane domains dif..:

Ousson, Solenne ; Saric, Arman ; Baguet, Aurelie...
Journal of Neurochemistry.  125 (2013)  4 - p. 610-619 , 2013
Link: https://doi.org/10.1111/..
 
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2

Development and Characterization of a Novel Membrane Assay ..:

Saric, Arman ; Brügge, Lars zur ; Müller-Pompalla, Dirk...
SLAS Discovery.  18 (2013)  3 - p. 277-285 , 2013
Link: https://doi.org/10.1177/..
 
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3

Orally bioavailable and brain-penetrant pyridazine and pyri..:

Huang, Yunhong ; Li, Ting ; Eatherton, Andrew...
Neuropharmacology.  70 (2013)  - p. 278-286 , 2013
Link: https://doi.org/10.1016/..
 
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4

Focal expression of adeno-associated viral-mutant tau induc..:

Dassie, Elisa ; Andrews, Melissa R. ; Bensadoun, Jean-Charles...
Neurobiology of Aging.  34 (2013)  5 - p. 1355-1368 , 2013
Link: https://doi.org/10.1016/..
 
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5

The Role of γ-Secretase Activating Protein (GSAP) and Imati..:

Hussain, Ishrut ; Fabrègue, Julien ; Anderes, Laurence...
Journal of Biological Chemistry.  288 (2013)  4 - p. 2521-2531 , 2013
Link: https://doi.org/10.1074/..
 
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6

γ‐Secretase modulators do not induce Aβ‐rebound and accumul..:

Li, Ting ; Huang, Yunhong ; Jin, Shiyi...
Journal of Neurochemistry.  121 (2012)  2 - p. 277-286 , 2012
Link: https://doi.org/10.1111/..
 
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7

Effects of the selective 5-HT7 receptor antagonist SB-26997..:

Waters, Kerry A. ; Stean, Tania O. ; Hammond, Beverley...
Behavioural Brain Research.  228 (2012)  1 - p. 211-218 , 2012
Link: https://doi.org/10.1016/..
 
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8

Pyridine-derived γ-secretase modulators:

Wan, Zehong ; Hall, Adrian ; Sang, Yingxia...
Bioorganic & Medicinal Chemistry Letters.  21 (2011)  16 - p. 4832-4835 , 2011
Link: https://doi.org/10.1016/..
 
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9

P3‐464: Establishment of a functional assay for studying al..:

Sand, Astrid ; Baguet, Aurelie ; Genoud, Stephane..
Alzheimer's & Dementia.  7 (2011)  4S_Part_19 - p. , 2011
Link: https://doi.org/10.1016/..
 
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10

Reduction in BACE1 decreases body weight, protects against ..:

Meakin, Paul J. ; Harper, Alex J. ; Hamilton, D. Lee...
Biochemical Journal.  441 (2011)  1 - p. 285-296 , 2011
Link: https://doi.org/10.1042/..
 
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11

P2‐234: Characterization of endogenous and exogenous gamma‐..:

Hussain, Ishrut ; Fabrègue, Julien ; Ousson, Solenne...
Alzheimer's & Dementia.  7 (2011)  4S_Part_11 - p. , 2011
Link: https://doi.org/10.1016/..
 
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12

Pyridazine-derived γ-secretase modulators:

Wan, Zehong ; Hall, Adrian ; Jin, Yun...
Bioorganic & Medicinal Chemistry Letters.  21 (2011)  13 - p. 4016-4019 , 2011
Link: https://doi.org/10.1016/..
 
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13

Piperidine-derived γ-secretase modulators:

Hall, Adrian ; Elliott, Richard L. ; Giblin, Gerard M.P....
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  3 - p. 1306-1311 , 2010
Link: https://doi.org/10.1016/..
 
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14

BACE-1 hydroxyethylamine inhibitors using novel edge-to-fac..:

Clarke, Brian ; Cutler, Leanne ; Demont, Emmanuel...
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  15 - p. 4639-4644 , 2010
Link: https://doi.org/10.1016/..
 
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15

Second generation of BACE-1 inhibitors. Part 1: The need fo..:

Charrier, Nicolas ; Clarke, Brian ; Cutler, Leanne...
Bioorganic & Medicinal Chemistry Letters.  19 (2009)  13 - p. 3664-3668 , 2009
Link: https://doi.org/10.1016/..
 
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