E-LIB Suche - Ergebnisse für: Johnson, Ted W

1

Design and Synthesis of Functionally Active 5-Amino-6-Aryl ..:

Gallego, Rebecca A. ; Bernier, Louise ; Chen, Hui...
Journal of Medicinal Chemistry. 66 (2023) 7 - p. 4888-4909 , 2023

Link: https://doi.org/10.1021/..

2

Analysis of lorlatinib analogs reveals a roadmap for target..:

Shiba-Ishii, Aya ; Johnson, Ted W. ; Dagogo-Jack, Ibiayi...
Nature Cancer. 3 (2022) 6 - p. 710-722 , 2022

Link: https://doi.org/10.1038/..

3

LTK fusions: A new target emerges in non-small cell lung ca..:

Cooper, Alissa J. ; Sequist, Lecia V. ; Johnson, Ted W..
Cancer Cell. 40 (2022) 1 - p. 23-25 , 2022

Link: https://doi.org/10.1016/..

4

Multiple conformational states of the HPK1 kinase domain in..:

Johnson, Eric ; McTigue, Michele ; Gallego, Rebecca A....
Journal of Biological Chemistry. 294 (2019) 23 - p. 9029-9036 , 2019

Link: https://doi.org/10.1074/..

5

Reviving B-Factors: Retrospective Normalized B-Factor Analy..:

Johnson, Ted W. ; Gallego, Rebecca A. ; Brooun, Alexei..
ACS Medicinal Chemistry Letters. 9 (2018) 9 - p. 878-883 , 2018

Link: https://doi.org/10.1021/..

6

Reviving B-Factors: Activating ALK Mutations Increase Prote..:

Johnson, Ted W. ; Bolanos, Ben ; Brooun, Alexei...
ACS Medicinal Chemistry Letters. 9 (2018) 9 - p. 872-877 , 2018

Link: https://doi.org/10.1021/..

7

Lipophilic Efficiency as an Important Metric in Drug Design:

Johnson, Ted W. ; Gallego, Rebecca A. ; Edwards, Martin P.
Journal of Medicinal Chemistry. 61 (2018) 15 - p. 6401-6420 , 2018

Link: https://doi.org/10.1021/..

8

The Axl kinase domain in complex with a macrocyclic inhibit..:

Gajiwala, Ketan S. ; Grodsky, Neil ; Bolaños, Ben...
Journal of Biological Chemistry. 292 (2017) 38 - p. 15705-15716 , 2017

Link: https://doi.org/10.1074/..

9

Conformational Studies and Atropisomerism Kinetics of the A..:

Elleraas, Jeff ; Ewanicki, Jason ; Johnson, Ted W....
Angewandte Chemie. 128 (2016) 11 - p. 3654-3659 , 2016

Link: https://doi.org/10.1002/..

10

Conformational Studies and Atropisomerism Kinetics of the A..:

Elleraas, Jeff ; Ewanicki, Jason ; Johnson, Ted W....
Angewandte Chemie International Edition. 55 (2016) 11 - p. 3590-3595 , 2016

Link: https://doi.org/10.1002/..

11

CNS Anticancer Drug Discovery and Development Conference Wh..:

Levin, Victor A. ; Tonge, Peter J. ; Gallo, James M....
Neuro-Oncology. 17 (2015) suppl 6 - p. vi1-vi26 , 2015

Link: https://doi.org/10.1093/..

12

PF-06463922 is a potent and selective next-generation ROS1/..:

Zou, Helen Y. ; Li, Qiuhua ; Engstrom, Lars D....
Proceedings of the National Academy of Sciences. 112 (2015) 11 - p. 3493-3498 , 2015

Link: https://doi.org/10.1073/..

13

PF-06463922 is a potent and selective next-generation ROS1/..:

Zou, Helen Y. ; Li, Qiuhua ; Engstrom, Lars D....
Proceedings of the National Academy of Sciences of the United States of America. 112 (2015) 11 - p. 3493-3498 , 2015

Link: https://www.jstor.org/st..

14

Effect of water solvation on the lipophilicity of isomeric ..:

Linton, Maria Angelica ; Burke, Benjamin J. ; Johnson, Ted W....
Bioorganic & Medicinal Chemistry. 23 (2015) 13 - p. 3408-3413 , 2015

Link: https://doi.org/10.1016/..

15

Discovery of (10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-o..:

Johnson, Ted W. ; Richardson, Paul F. ; Bailey, Simon...
Journal of Medicinal Chemistry. 57 (2014) 11 - p. 4720-4744 , 2014

Link: https://doi.org/10.1021/..