E-LIB Suche - Ergebnisse für: Juraj Velcicky

1

Ligandability Assessment of IL-1β by Integrated Hit Identif..:

Vulpetti, Anna ; Rondeau, Jean-Michel ; Bellance, Marie-Hélène...
Journal of Medicinal Chemistry. 67 (2024) 10 - p. 8141-8160 , 2024

Link: https://doi.org/10.1021/..

2

Discovery of Potent, Orally Bioavailable, Tricyclic NLRP3 I..:

Velcicky, Juraj ; Janser, Philipp ; Gommermann, Nina...
Journal of Medicinal Chemistry. 67 (2024) 2 - p. 1544-1562 , 2024

Link: https://doi.org/10.1021/..

3

The Proton-Sensing GPR4 Receptor Regulates Paracellular Gap..:

Krewson, Elizabeth A. ; Sanderlin, Edward J. ; Marie, Mona A....
iScience. 23 (2020) 2 - p. 100848 , 2020

Link: https://doi.org/10.1016/..

4

Discovery and Optimization of Novel SUCNR1 Inhibitors: Desi..:

Velcicky, Juraj ; Wilcken, Rainer ; Cotesta, Simona...
Journal of Medicinal Chemistry. 63 (2020) 17 - p. 9856-9875 , 2020

Link: https://doi.org/10.1021/..

5

Pharmacological inhibition of GPR4 remediates intestinal in..:

Sanderlin, Edward J. ; Marie, Mona ; Velcicky, Juraj..
European Journal of Pharmacology. 852 (2019) - p. 218-230 , 2019

Link: https://doi.org/10.1016/..

6

Discovery of Orally Active Hydroxyethylamine Based SPPL2a I..:

Velcicky, Juraj ; Mathison, Casey J. N. ; Nikulin, Victor...
ACS Medicinal Chemistry Letters. 10 (2019) 6 - p. 887-892 , 2019

Link: https://doi.org/10.1021/..

7

Modulating ADME Properties by Fluorination: MK2 Inhibitors ..:

Velcicky, Juraj ; Schlapbach, Achim ; Heng, Richard...
ACS Medicinal Chemistry Letters. 9 (2018) 4 - p. 392-396 , 2018

Link: https://doi.org/10.1021/..

8

Discovery of the First Potent, Selective, and Orally Bioava..:

Velcicky, Juraj ; Bodendorf, Ursula ; Rigollier, Pascal...
Journal of Medicinal Chemistry. 61 (2018) 3 - p. 865-880 , 2018

Link: https://doi.org/10.1021/..

9

Design and synthesis of potent and orally active GPR4 antag..:

Miltz, Wolfgang ; Velcicky, Juraj ; Dawson, Janet...
Bioorganic & Medicinal Chemistry. 25 (2017) 16 - p. 4512-4525 , 2017

Link: https://doi.org/10.1016/..

10

Development of Selective, Orally Active GPR4 Antagonists wi..:

Velcicky, Juraj ; Miltz, Wolfgang ; Oberhauser, Berndt...
Journal of Medicinal Chemistry. 60 (2017) 9 - p. 3672-3683 , 2017

Link: https://doi.org/10.1021/..

11

Nucleoside Analogues with a 1,3‐DieneFe(CO)3 Substructure:..:

Hirschhäuser, Christoph ; Velcicky, Juraj ; Schlawe, Daniel...
Chemistry – A European Journal. 19 (2013) 39 - p. 13017-13029 , 2013

Link: https://doi.org/10.1002/..

12

Palladium-Catalyzed Cyanomethylation of Aryl Halides throug..:

Velcicky, Juraj ; Soicke, Arne ; Steiner, Roland.
Journal of the American Chemical Society. 133 (2011) 18 - p. 6948-6951 , 2011

Link: https://doi.org/10.1021/..

13

Novel 3-aminopyrazole inhibitors of MK-2 discovered by scaf..:

Velcicky, Juraj ; Feifel, Roland ; Hawtin, Stuart...
Bioorganic & Medicinal Chemistry Letters. 20 (2010) 3 - p. 1293-1297 , 2010

Link: https://doi.org/10.1016/..

14

In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inh..:

Revesz, Laszlo ; Schlapbach, Achim ; Aichholz, Reiner...
Bioorganic & Medicinal Chemistry Letters. 20 (2010) 15 - p. 4715-4718 , 2010

Link: https://doi.org/10.1016/..

15

In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inh..:

Revesz, Laszlo ; Schlapbach, Achim ; Aichholz, Reiner...
Bioorganic & Medicinal Chemistry Letters. 20 (2010) 15 - p. 4719-4723 , 2010

Link: https://doi.org/10.1016/..