E-LIB Suche - Ergebnisse für: Käck, Helena

1

The structures of salt-inducible kinase 3 in complex with i..:

Öster, Linda ; Castaldo, Marie ; de Vries, Emma...
Journal of Biological Chemistry. 300 (2024) 5 - p. 107201 , 2024

Link: https://doi.org/10.1016/..

2

A cell-active cyclic peptide targeting the Nrf2/Keap1 prote..:

Iegre, Jessica ; Krajcovicova, Sona ; Gunnarsson, Anders...
Chemical Science. 14 (2023) 39 - p. 10800-10805 , 2023

Link: https://doi.org/10.1039/..

3

Combining structural and coevolution information to unveil ..:

La Sala, Giuseppina ; Pfleger, Christopher ; Käck, Helena...
Chemical Science. 14 (2023) 25 - p. 7057-7067 , 2023

Link: https://doi.org/10.1039/..

4

Discovery and optimization of cyclohexane-1,4-diamines as a..:

Schiesser, Stefan ; Hajek, Peter ; Pople, Huw E....
European Journal of Medicinal Chemistry. 227 (2022) - p. 113925 , 2022

Link: https://doi.org/10.1016/..

5

Machine learning/molecular dynamic protein structure predic..:

Audagnotto, Martina ; Czechtizky, Werngard ; De Maria, Leonardo...
Scientific Reports. 12 (2022) 1 - p. , 2022

Link: https://doi.org/10.1038/..

6

Fragment-Based Discovery of Novel Allosteric MEK1 Binders:

Di Fruscia, Paolo ; Edfeldt, Fredrik ; Shamovsky, Igor...
ACS Medicinal Chemistry Letters. 12 (2021) 2 - p. 302-308 , 2021

Link: https://doi.org/10.1021/..

7

Discovery of the Oral Leukotriene C4 Synthase Inhibitor (1S..:

Munck af Rosenschöld, Magnus ; Johannesson, Petra ; Nikitidis, Antonios...
Journal of Medicinal Chemistry. 62 (2019) 17 - p. 7769-7787 , 2019

Link: https://doi.org/10.1021/..

8

An Angle on MK2 Inhibition—Optimization and Evaluation of P..:

Hedström, Ulf ; Norberg, Monica ; Evertsson, Emma...
ChemMedChem. 14 (2019) 19 - p. 1701-1709 , 2019

Link: https://doi.org/10.1002/..

9

DPP1 Inhibitors: Exploring the Role of Water in the S2 Pock..:

Käck, Helena ; Doyle, Kevin ; Hughes, Samantha J....
ACS Medicinal Chemistry Letters. 10 (2019) 8 - p. 1222-1227 , 2019

Link: https://doi.org/10.1021/..

10

Front Cover: An Angle on MK2 Inhibition—Optimization and Ev..:

Hedström, Ulf ; Norberg, Monica ; Evertsson, Emma...
ChemMedChem. 14 (2019) 19 - p. 1692-1692 , 2019

Link: https://doi.org/10.1002/..

11

X-ray Characterization and Structure-Based Optimization of ..:

Witten, Michael R. ; Wissler, Lisa ; Snow, Melanie...
Journal of Medicinal Chemistry. 60 (2017) 22 - p. 9299-9319 , 2017

Link: https://doi.org/10.1021/..

12

Discovery of Second Generation Reversible Covalent DPP1 Inh..:

Doyle, Kevin ; Lönn, Hans ; Käck, Helena...
Journal of Medicinal Chemistry. 59 (2016) 20 - p. 9457-9472 , 2016

Link: https://doi.org/10.1021/..

13

Potent and Selective Inhibitors of MTH1 Probe Its Role in C..:

Kettle, Jason G. ; Alwan, Husam ; Bista, Michal...
Journal of Medicinal Chemistry. 59 (2016) 6 - p. 2346-2361 , 2016

Link: https://doi.org/10.1021/..

14

Successful generation of structural information for fragmen..:

Öster, Linda ; Tapani, Sofia ; Xue, Yafeng.
Drug Discovery Today. 20 (2015) 9 - p. 1104-1111 , 2015

Link: https://doi.org/10.1016/..

15

Design of inhibitors of Helicobacter pylori glutamate racem..:

Basarab, Gregory S. ; Hill, Pamela ; Eyermann, Charles J....
Bioorganic & Medicinal Chemistry Letters. 22 (2012) 17 - p. 5600-5607 , 2012

Link: https://doi.org/10.1016/..