E-LIB Suche - Ergebnisse für: Kharel, Yugesh

1

Assay of Sphingosine 1-phosphate Transporter Spinster Homol..:

Kharel, Yugesh ; Huang, Tao ; Santos, Webster L..
SLAS Discovery. 28 (2023) 6 - p. 284-287 , 2023

2

Imidazole-based sphingosine-1-phosphate transporter Spns2 i..:

Shrader, Christopher W. ; Foster, Daniel ; Kharel, Yugesh...
Bioorganic & Medicinal Chemistry Letters. 96 (2023) - p. 129516 , 2023

Link: https://doi.org/10.1016/..

3

2-Aminobenzoxazole Derivatives as Potent Inhibitors of the ..:

Burgio, Ariel L. ; Shrader, Christopher W. ; Kharel, Yugesh...
Journal of Medicinal Chemistry. 66 (2023) 8 - p. 5873-5891 , 2023

Link: https://doi.org/10.1021/..

4

A Novel Sphingosine Kinase Inhibitor Suppresses Chikungunya..:

Oyewole, Opeoluwa O. ; Dunnavant, Kyle ; Bhattarai, Shaurav...
Viruses. 14 (2022) 6 - p. 1123 , 2022

Link: https://doi.org/10.3390/..

5

Discovery of In Vivo Active Sphingosine-1-phosphate Transpo..:

Fritzemeier, Russell ; Foster, Daniel ; Peralta, Ashley...
Journal of Medicinal Chemistry. 65 (2022) 11 - p. 7656-7681 , 2022

Link: https://doi.org/10.1021/..

6

Sphingosine Kinase 2 Inhibitors: Rigid Aliphatic Tail Deriv..:

Pashikanti, Srinath ; Foster, Daniel J. ; Kharel, Yugesh...
ACS Bio & Med Chem Au. 2 (2022) 5 - p. 469-489 , 2022

Link: https://doi.org/10.1021/..

7

Lipophilic tail modifications of 2-(hydroxymethyl)pyrrolidi..:

Li, Hao ; Sibley, Christopher D. ; Kharel, Yugesh...
Bioorganic & Medicinal Chemistry. 30 (2021) - p. 115941 , 2021

Link: https://doi.org/10.1016/..

8

Probing the substitution pattern of indole-based scaffold r..:

Congdon, Molly ; Fritzemeier, Russell G. ; Kharel, Yugesh...
European Journal of Medicinal Chemistry. 212 (2021) - p. 113121 , 2021

Link: https://doi.org/10.1016/..

9

Mechanism of sphingosine 1-phosphate clearance from blood:

Kharel, Yugesh ; Huang, Tao ; Salamon, Anita...
Biochemical Journal. 477 (2020) 5 - p. 925-935 , 2020

Link: https://doi.org/10.1042/..

10

Discovery of a Small Side Cavity in Sphingosine Kinase 2 th..:

Sibley, Christopher D. ; Morris, Emily A. ; Kharel, Yugesh...
Journal of Medicinal Chemistry. 63 (2020) 3 - p. 1178-1198 , 2020

Link: https://doi.org/10.1021/..

11

Photoacoustic microscopy reveals the hemodynamic basis of s..:

Cao, Rui ; Li, Jun ; Kharel, Yugesh...
Theranostics. 8 (2018) 22 - p. 6111-6120 , 2018

Link: https://doi.org/10.7150/..

12

Saccharomyces cerevisiae as a platform for assessing sphing..:

Kharel, Yugesh ; Agah, Sayeh ; Huang, Tao...
PLOS ONE. 13 (2018) 4 - p. e0192179 , 2018

Link: https://doi.org/10.1371/..

13

Transforming Sphingosine Kinase 1 Inhibitors into Dual and ..:

Childress, Elizabeth S. ; Kharel, Yugesh ; Brown, Anne M....
Journal of Medicinal Chemistry. 60 (2017) 9 - p. 3933-3957 , 2017

Link: https://doi.org/10.1021/..

14

Structural Requirements and Docking Analysis of Amidine-Bas..:

Houck, Joseph D. ; Dawson, Thomas K. ; Kennedy, Andrew J....
ACS Medicinal Chemistry Letters. 7 (2016) 5 - p. 487-492 , 2016

Link: https://doi.org/10.1021/..

15

Structure–Activity Relationship Studies and Molecular Model..:

Congdon, Molly D. ; Kharel, Yugesh ; Brown, Anne M....
ACS Medicinal Chemistry Letters. 7 (2016) 3 - p. 229-234 , 2016

Link: https://doi.org/10.1021/..