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Kulyk, Svitlana
53  Ergebnisse:
Personensuche X
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1

MRTX1719 Is an MTA-Cooperative PRMT5 Inhibitor That Exhibit..:

Engstrom, Lars D. ; Aranda, Ruth ; Waters, Laura...
Cancer Discovery.  13 (2023)  11 - p. 2412-2431 , 2023
Link: https://doi.org/10.1158/..
 
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2

Lung-restricted ALK5 inhibition avoids systemic toxicities ..:

Maher, Jonathan M. ; Zhang, Rui ; Palanisamy, Gopinath...
Toxicology and Applied Pharmacology.  438 (2022)  - p. 115905 , 2022
Link: https://doi.org/10.1016/..
 
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3

Design and Discovery of MRTX0902, a Potent, Selective, Brai..:

Ketcham, John M. ; Haling, Jacob ; Khare, Shilpi...
Journal of Medicinal Chemistry.  65 (2022)  14 - p. 9678-9690 , 2022
Link: https://doi.org/10.1021/..
 
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4

Fragment-Based Discovery of MRTX1719, a Synthetic Lethal In..:

Smith, Christopher R. ; Aranda, Ruth ; Bobinski, Thomas P....
Journal of Medicinal Chemistry.  65 (2022)  3 - p. 1749-1766 , 2022
Link: https://doi.org/10.1021/..
 
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5

Atropisomeric Racemization Kinetics of MRTX1719 Using Chira..:

Kulyk, Svitlana ; De Paul, Susan M. ; Marx, Matthew A...
ACS Omega.  7 (2022)  36 - p. 32062-32067 , 2022
Link: https://doi.org/10.1021/..
 
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6

Fragment optimization and elaboration strategies – the disc..:

Smith, Christopher R. ; Kulyk, Svitlana ; Ahmad, Misbha Ud Din...
RSC Medicinal Chemistry.  13 (2022)  12 - p. 1549-1564 , 2022
Link: https://doi.org/10.1039/..
 
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7

Design and evaluation of achiral, non-atropisomeric 4-(amin..:

Smith, Christopher R. ; Aranda, Ruth ; Christensen, James G....
Bioorganic & Medicinal Chemistry.  71 (2022)  - p. 116947 , 2022
Link: https://doi.org/10.1016/..
 
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8

A Unifying Synthesis Approach to the C18-, C19-, and C20-Di..:

Kou, Kevin G. M. ; Kulyk, Svitlana ; Marth, Christopher J....
Journal of the American Chemical Society.  139 (2017)  39 - p. 13882-13896 , 2017
Link: https://doi.org/10.1021/..
 
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9

Enyne [4+4] Cycloaddition/Oxidation: Ring Contraction via C..:

Kulyk, Svitlana ; Khatri, Buddha B. ; Sieburth, Scott McN.
Angewandte Chemie.  129 (2016)  1 - p. 325-329 , 2016
Link: https://doi.org/10.1002/..
 
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10

Enyne [4+4] Cycloaddition/Oxidation: Ring Contraction via C..:

Kulyk, Svitlana ; Khatri, Buddha B. ; Sieburth, Scott McN.
Angewandte Chemie International Edition.  56 (2016)  1 - p. 319-323 , 2016
Link: https://doi.org/10.1002/..
 
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11

Correction: Enyne [4 + 4] photocycloaddition with polycycli..:

Khatri, Buddha B. ; Kulyk, Svitlana ; Sieburth, Scott McN.
Organic Chemistry Frontiers.  2 (2015)  3 - p. 300-300 , 2015
Link: https://doi.org/10.1039/..
 
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12

Formation and isomerization of polycyclic 1,5-enynes:

Finn, Paul B. ; Kulyk, Svitlana ; Sieburth, Scott McN.
Tetrahedron Letters.  56 (2015)  23 - p. 3567-3570 , 2015
Link: https://doi.org/10.1016/..
 
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13

Stabilization, Isomerization and Rearrangement of Enyne [4 ..:

Kulyk, Svitlana ; Khatri, Buddha B. ; Sieburth, Scott McN.
Organic Letters.  16 (2014)  16 - p. 4138-4141 , 2014
Link: https://doi.org/10.1021/..
 
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14

Enyne [4 + 4] photocycloaddition with polycyclic aromatics:

Khatri, Buddha B. ; Kulyk, Svitlana ; Sieburth, Scott McN.
Org. Chem. Front..  1 (2014)  8 - p. 961-964 , 2014
Link: https://doi.org/10.1039/..
 
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15

Intramolecular Pyridone/Enyne Photocycloaddition: Partition..:

Kulyk, Svitlana ; Dougherty Jr., William G. ; Kassel, W. Scott..
Organic Letters.  13 (2011)  9 - p. 2180-2183 , 2011
Link: https://doi.org/10.1021/..
 
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