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Genome wide CRISPR screen for Pasteurella multocida toxin (..:
Schoellkopf, Julian ; Mueller, Thomas ; Hippchen, Lena...
PLOS Pathogens. 18 (2022) 12 - p. e1010781 , 2022
PLOS Pathogens. 18 (2022) 12 - p. e1010781 , 2022
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2
Genome wide CRISPR screen for Pasteurella multocida toxin (..:
Julian Schoellkopf ; Thomas Mueller ; Lena Hippchen...
https://doi.org/10.1371/journal.ppat.1010781. , 2022
https://doi.org/10.1371/journal.ppat.1010781. , 2022
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3
Solid-phase binding assay of PMT to clusters 2, 3, and 4 of..:
Julian Schoellkopf (14259688) ; Thomas Mueller (33067) ; Lena Hippchen (14259691)...
https://figshare.com/articles/figure/Solid-phase_binding_assay_of_PMT_to_clusters_2_3_and_4_of_LRP1_/21727549. , 2022
https://figshare.com/articles/figure/Solid-phase_binding_assay_of_PMT_to_clusters_2_3_and_4_of_LRP1_/21727549. , 2022
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4
Antibodies used in this study:
Julian Schoellkopf (14259688) ; Thomas Mueller (33067) ; Lena Hippchen (14259691)...
https://figshare.com/articles/dataset/Antibodies_used_in_this_study_/21727558. , 2022
https://figshare.com/articles/dataset/Antibodies_used_in_this_study_/21727558. , 2022
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5
Expression levels of LRP1 do not exclusively determine the ..:
Julian Schoellkopf (14259688) ; Thomas Mueller (33067) ; Lena Hippchen (14259691)...
https://figshare.com/articles/journal_contribution/Expression_levels_of_LRP1_do_not_exclusively_determine_the_efficiency_of_intoxication_/21727534. , 2022
https://figshare.com/articles/journal_contribution/Expression_levels_of_LRP1_do_not_exclusively_determine_the_efficiency_of_intoxication_/21727534. , 2022
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6
Schematic presentation of the toxins used:
Julian Schoellkopf (14259688) ; Thomas Mueller (33067) ; Lena Hippchen (14259691)...
https://figshare.com/articles/journal_contribution/Schematic_presentation_of_the_toxins_used_/21727525. , 2022
https://figshare.com/articles/journal_contribution/Schematic_presentation_of_the_toxins_used_/21727525. , 2022
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7
Oligonucelotides used in this study:
Julian Schoellkopf (14259688) ; Thomas Mueller (33067) ; Lena Hippchen (14259691)...
https://figshare.com/articles/dataset/Oligonucelotides_used_in_this_study_/21727555. , 2022
https://figshare.com/articles/dataset/Oligonucelotides_used_in_this_study_/21727555. , 2022
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8
LRP1 knockout prohibits binding and uptake of PMT:
Julian Schoellkopf (14259688) ; Thomas Mueller (33067) ; Lena Hippchen (14259691)...
https://figshare.com/articles/figure/LRP1_knockout_prohibits_binding_and_uptake_of_PMT_/21727543. , 2022
https://figshare.com/articles/figure/LRP1_knockout_prohibits_binding_and_uptake_of_PMT_/21727543. , 2022
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9
Volcano plot showing significantly enriched genes:
Julian Schoellkopf (14259688) ; Thomas Mueller (33067) ; Lena Hippchen (14259691)...
https://figshare.com/articles/figure/Volcano_plot_showing_significantly_enriched_genes_/21727540. , 2022
https://figshare.com/articles/figure/Volcano_plot_showing_significantly_enriched_genes_/21727540. , 2022
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10
Table depicting the 10 mostly enriched sgRNAs and the funct..:
Julian Schoellkopf (14259688) ; Thomas Mueller (33067) ; Lena Hippchen (14259691)...
https://figshare.com/articles/journal_contribution/Table_depicting_the_10_mostly_enriched_sgRNAs_and_the_function_of_the_targeted_genes_/21727531. , 2022
https://figshare.com/articles/journal_contribution/Table_depicting_the_10_mostly_enriched_sgRNAs_and_the_function_of_the_targeted_genes_/21727531. , 2022
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11
LRP1 knockout or competitive inhibition of LRP1 inhibit mod..:
Julian Schoellkopf (14259688) ; Thomas Mueller (33067) ; Lena Hippchen (14259691)...
https://figshare.com/articles/figure/LRP1_knockout_or_competitive_inhibition_of_LRP1_inhibit_modification_of_PMT_/21727546. , 2022
https://figshare.com/articles/figure/LRP1_knockout_or_competitive_inhibition_of_LRP1_inhibit_modification_of_PMT_/21727546. , 2022
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12
Expression of LRP1 or LRP1 cluster 4 in MEF-LRP1 -/- cells ..:
Julian Schoellkopf (14259688) ; Thomas Mueller (33067) ; Lena Hippchen (14259691)...
https://figshare.com/articles/figure/Expression_of_LRP1_or_LRP1_cluster_4_in_MEF-LRP1_sup_-_-_sup_cells_restores_the_ability_of_PMT_to_intoxicate_cells_/21727552. , 2022
https://figshare.com/articles/figure/Expression_of_LRP1_or_LRP1_cluster_4_in_MEF-LRP1_sup_-_-_sup_cells_restores_the_ability_of_PMT_to_intoxicate_cells_/21727552. , 2022
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13
Schematic presentation of the CRISPR/Cas9-Knock out screen:
Julian Schoellkopf (14259688) ; Thomas Mueller (33067) ; Lena Hippchen (14259691)...
https://figshare.com/articles/figure/Schematic_presentation_of_the_CRISPR_Cas9-Knock_out_screen_/21727537. , 2022
https://figshare.com/articles/figure/Schematic_presentation_of_the_CRISPR_Cas9-Knock_out_screen_/21727537. , 2022
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14
Genome wide CRISPR screen for Pasteurella multocida toxin (..:
Schöllkopf, Julian ; Mueller, Thomas ; Hippchen, Lena...
https://freidok.uni-freiburg.de/data/232251. , 2022
https://freidok.uni-freiburg.de/data/232251. , 2022