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Lessard, Christian B
235  Ergebnisse:
Personensuche X
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1

The tauopathy‐associated PERK variant, PERK‐B, induces mala..:

Lessard, Christian B ; Tolton, Samantha G ; McFarland, Karen...
Alzheimer's & Dementia.  19 (2023)  S24 - p. , 2023
Link: https://doi.org/10.1002/..
 
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2

Tau‐RNA complexes contribute to the pathogenesis and progre..:

Lessard, Christian B ; Koren III, John ; Abisambra, Jose F. F
Alzheimer's & Dementia.  18 (2022)  S4 - p. , 2022
Link: https://doi.org/10.1002/..
 
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3

Hypomorphic PERK promotes a maladaptive phenotype in respon..:

Lessard, Christian B ; Tolton, Samantha G ; Abisambra, Jose F. F
Alzheimer's & Dementia.  18 (2022)  S4 - p. , 2022
Link: https://doi.org/10.1002/..
 
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4

Deletion of Abi3/Gngt2 influences age-progressive amyloid β..:

Ibanez, Kristen R. ; McFarland, Karen N. ; Phillips, Jennifer...
Alzheimer's Research & Therapy.  14 (2022)  1 - p. , 2022
Link: https://doi.org/10.1186/..
 
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5

Targeting aggregated tau turnover as a therapeutic strategy:

Croft, Cara L ; Goodwin, Marshall S ; Ryu, Daniel H...
Alzheimer's & Dementia.  17 (2021)  S3 - p. , 2021
Link: https://doi.org/10.1002/..
 
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6

Photodynamic studies reveal rapid formation and appreciable..:

Croft, Cara L. ; Goodwin, Marshall S. ; Ryu, Daniel H....
Acta Neuropathologica.  141 (2021)  3 - p. 359-381 , 2021
Link: https://doi.org/10.1007/..
 
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7

γ-Secretase modulators exhibit selectivity for modulation o..:

Lessard, Christian B. ; Rodriguez, Edgardo ; Ladd, Thomas B....
Alzheimer's Research & Therapy.  12 (2020)  1 - p. , 2020
Link: https://doi.org/10.1186/..
 
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8

Individual and combined presenilin 1 and 2 knockouts reveal..:

Lessard, Christian B. ; Rodriguez, Edgardo ; Ladd, Thomas B....
Journal of Biological Chemistry.  294 (2019)  29 - p. 11276-11285 , 2019
Link: https://doi.org/10.1074/..
 
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9

Alzheimer's disease phospholipase C-gamma-2 (PLCG2) protect..:

Magno, Lorenza ; Lessard, Christian B. ; Martins, Marta...
Alzheimer's Research & Therapy.  11 (2019)  1 - p. , 2019
Link: https://doi.org/10.1186/..
 
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10

High‐affinity interactions and signal transduction between ..:

Lessard, Christian B ; Malnik, Samuel L ; Zhou, Yingyue...
EMBO Molecular Medicine.  10 (2018)  11 - p. , 2018
Link: https://doi.org/10.15252..
 
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11

γ‐Secretase inhibitors in cancer clinical trials are pharma..:

Ran, Yong ; Hossain, Fokhrul ; Pannuti, Antonio...
EMBO Molecular Medicine.  9 (2017)  7 - p. 950-966 , 2017
Link: https://doi.org/10.15252..
 
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12

γ-Secretase Modulators and APH1 Isoforms Modulate γ-Secreta..:

Lessard, Christian B. ; Cottrell, Barbara A. ; Maruyama, Hiroko...
PLOS ONE.  10 (2015)  12 - p. e0144758 , 2015
Link: https://doi.org/10.1371/..
 
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13

Substrate Sequence Influences γ-Secretase Modulator Activit..:

Sagi, Sarah A. ; Lessard, Christian B. ; Winden, Kellen D....
Journal of Biological Chemistry.  286 (2011)  46 - p. 39794-39803 , 2011
Link: https://doi.org/10.1074/..
 
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14

And four equals one: Presenilin takes the γ-secretase role ..:

Lessard, Christian B. ; Wagner, Steven L. ; Koo, Edward H.
Proceedings of the National Academy of Sciences of the United States of America.  107 (2010)  50 - p. 21236-21237 , 2010
Link: https://www.jstor.org/st..
 
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15

And four equals one: Presenilin takes the γ-secretase role ..:

Lessard, Christian B. ; Wagner, Steven L. ; Koo, Edward H.
Proceedings of the National Academy of Sciences.  107 (2010)  50 - p. 21236-21237 , 2010
Link: https://doi.org/10.1073/..
 
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