E-LIB Suche - Ergebnisse für: Liu, Jim (Jiwen)

1

Solving time-dependent CYP3A4 inhibition for a series of in..:

Johnson, Michael G. ; Liu, Jim (Jiwen) ; Li, An-Rong...
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 13 - p. 2877-2880 , 2014

Link: https://doi.org/10.1016/..

2

Discovery of the imidazole-derived GPR40 agonist AM-3189:

Ma, Zhihua ; Lin, Daniel C.-H. ; Sharma, Rajiv...
Bioorganic & Medicinal Chemistry Letters. 26 (2016) 1 - p. 15-20 , 2016

Link: https://doi.org/10.1016/..

3

Discovery and optimization of N-(3-(1,3-dioxo-2,3-dihydro-1..:

Yu, Ming ; (Ken) Zhang, Jian ; Wang, Yingcai...
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 1 - p. 156-160 , 2014

Link: https://doi.org/10.1016/..

4

Discovery of Potent and Simplified Piperidinone-Based Inhib..:

Yu, Ming ; Wang, Yingcai ; Zhu, Jiang...
ACS Medicinal Chemistry Letters. 5 (2014) 8 - p. 894-899 , 2014

Link: https://doi.org/10.1021/..

5

Optimization beyond AMG 232: Discovery and SAR of sulfonami..:

Wang, Yingcai ; Zhu, Jiang ; Liu, Jiwen (Jim)...
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 16 - p. 3782-3785 , 2014

Link: https://doi.org/10.1016/..

6

Optimization of GPR40 Agonists for Type 2 Diabetes:

Liu, Jiwen (Jim) ; Wang, Yingcai ; Ma, Zhihua...
ACS Medicinal Chemistry Letters. 5 (2014) 5 - p. 517-521 , 2014

Link: https://doi.org/10.1021/..

7

Improving the Pharmacokinetics of GPR40/FFA1 Full Agonists:

Du, Xiaohui ; Dransfield, Paul J. ; Lin, Daniel C.-H....
ACS Medicinal Chemistry Letters. 5 (2014) 4 - p. 384-389 , 2014

Link: https://doi.org/10.1021/..

8

Discovery of AMG 232, a Potent, Selective, and Orally Bioav..:

Sun, Daqing ; Li, Zhihong ; Rew, Yosup...
Journal of Medicinal Chemistry. 57 (2014) 4 - p. 1454-1472 , 2014

Link: https://doi.org/10.1021/..

9

Discovery and optimization of 5-(2-((1-(phenylsulfonyl)-1,2..:

Wang, Yingcai ; Yu, Ming ; Zhu, Jiang...
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 4 - p. 1133-1137 , 2014

Link: https://doi.org/10.1016/..

10

Discovery and optimization of arylsulfonyl 3-(pyridin-2-ylo..:

Zhang, Jian (Ken) ; Li, An-Rong ; Yu, Ming...
Bioorganic & Medicinal Chemistry Letters. 23 (2013) 12 - p. 3609-3613 , 2013

Link: https://doi.org/10.1016/..

11

Activation of FFA1 mediates GLP-1 secretion in mice. Eviden..:

Xiong, Yumei ; Swaminath, Gayathri ; Cao, Qiong...
Molecular and Cellular Endocrinology. 369 (2013) 1-2 - p. 119-129 , 2013

Link: https://doi.org/10.1016/..

12

Discovery and Optimization of Potent GPR40 Full Agonists Co..:

Wang, Yingcai ; Liu, Jiwen (Jim) ; Dransfield, Paul J....
ACS Medicinal Chemistry Letters. 4 (2013) 6 - p. 551-555 , 2013

Link: https://doi.org/10.1021/..

13

Aminopyrazole–Phenylalanine Based GPR142 Agonists: Discover..:

Yu, Ming ; Lizarzaburu, Mike ; Motani, Alykhan...
ACS Medicinal Chemistry Letters. 4 (2013) 9 - p. 829-834 , 2013

Link: https://doi.org/10.1021/..

14

Why Do SGLT2 Inhibitors Inhibit Only 30–50% of Renal Glucos..:

Liu, Jiwen (Jim) ; Lee, TaeWeon ; DeFronzo, Ralph A.
Diabetes. 61 (2012) 9 - p. 2199-2204 , 2012

Link: https://doi.org/10.2337/..

15

Optimization of phenylacetic acid derivatives for balanced ..:

Liu, Jiwen (Jim) ; Wang, Yingcai ; Johnson, Michael G....
Bioorganic & Medicinal Chemistry Letters. 22 (2012) 4 - p. 1686-1689 , 2012

Link: https://doi.org/10.1016/..