E-LIB Suche - Ergebnisse für: Lorthiois, Edwige

1

JDQ443, a Structurally Novel, Pyrazole-Based, Covalent Inhi..:

Lorthiois, Edwige ; Gerspacher, Marc ; Beyer, Kim S....
Journal of Medicinal Chemistry. 65 (2022) 24 - p. 16173-16203 , 2022

Link: https://doi.org/10.1021/..

2

Discovery, Preclinical Characterization, and Early Clinical..:

Weiss, Andreas ; Lorthiois, Edwige ; Barys, Louise...
Cancer Discovery. 12 (2022) 6 - p. 1500-1517 , 2022

Link: https://doi.org/10.1158/..

3

Structure-Based Design and Preclinical Characterization of ..:

Lorthiois, Edwige ; Roache, James ; Barnes-Seeman, David...
Journal of Medicinal Chemistry. 63 (2020) 15 - p. 8088-8113 , 2020

Link: https://doi.org/10.1021/..

4

Design, Synthesis, and Preclinical Characterization of Sele..:

Karki, Rajeshri G. ; Powers, James ; Mainolfi, Nello...
Journal of Medicinal Chemistry. 62 (2019) 9 - p. 4656-4668 , 2019

Link: https://doi.org/10.1021/..

5

Discovery and Design of First Benzylamine-Based Ligands Bin..:

Vulpetti, Anna ; Ostermann, Nils ; Randl, Stefan...
ACS Medicinal Chemistry Letters. 9 (2018) 5 - p. 490-495 , 2018

Link: https://doi.org/10.1021/..

6

Structure-Based Library Design and Fragment Screening for t..:

Vulpetti, Anna ; Randl, Stefan ; Rüdisser, Simon...
Journal of Medicinal Chemistry. 60 (2017) 5 - p. 1946-1958 , 2017

Link: https://doi.org/10.1021/..

7

Discovery of Highly Potent and Selective Small-Molecule Rev..:

Lorthiois, Edwige ; Anderson, Karen ; Vulpetti, Anna...
Journal of Medicinal Chemistry. 60 (2017) 13 - p. 5717-5735 , 2017

Link: https://doi.org/10.1021/..

8

trans -(3 S ,4 S )-Disubstituted pyrrolidines as inhibitors..:

Lorthiois, Edwige ; Cumin, Frederic ; Ehrhardt, Claus...
Bioorganic & Medicinal Chemistry Letters. 25 (2015) 8 - p. 1782-1786 , 2015

Link: https://doi.org/10.1016/..

9

trans -3,4-Disubstituted pyrrolidines as inhibitors of the ..:

Sellner, Holger ; Cottens, Sylvain ; Cumin, Frédéric...
Bioorganic & Medicinal Chemistry Letters. 25 (2015) 8 - p. 1787-1791 , 2015

Link: https://doi.org/10.1016/..

10

Fluorescence Lifetime–Based Competitive Binding Assays for ..:

Boettcher, Andreas ; Gradoux, Nathalie ; Lorthiois, Edwige...
SLAS Discovery. 19 (2014) 6 - p. 870-877 , 2014

Link: https://doi.org/10.1177/..

11

The Discovery of Novel Potent trans-3,4-Disubstituted Pyrro..:

Lorthiois, Edwige ; Breitenstein, Werner ; Cumin, Frederic...
Journal of Medicinal Chemistry. 56 (2013) 6 - p. 2207-2217 , 2013

Link: https://doi.org/10.1021/..

12

A sensitive fluorescence intensity assay for deubiquitinati..:

Hassiepen, Ulrich ; Eidhoff, Ulf ; Meder, Gabriele...
Analytical Biochemistry. 371 (2007) 2 - p. 201-207 , 2007

Link: https://doi.org/10.1016/..

13

Discovery of thiadiazoles as a novel structural class of po..:

Vergne, Fabrice ; Bernardelli, Patrick ; Lorthiois, Edwige...
Bioorganic & Medicinal Chemistry Letters. 14 (2004) 18 - p. 4615-4621 , 2004

Link: https://doi.org/10.1016/..

14

Resolution of trans-3-aminocyclohexanol:

Bernardelli, Patrick ; Bladon, Michael ; Lorthiois, Edwige...
Tetrahedron: Asymmetry. 15 (2004) 9 - p. 1451-1455 , 2004

Link: https://doi.org/10.1016/..

15

Spiroquinazolinones as novel, potent, and selective PDE7 in..:

Bernardelli, Patrick ; Lorthiois, Edwige ; Vergne, Fabrice...
Bioorganic & Medicinal Chemistry Letters. 14 (2004) 18 - p. 4627-4631 , 2004

Link: https://doi.org/10.1016/..