E-LIB Suche - Ergebnisse für: Macdonald, Gregor

1

A Brain-Penetrant and Bioavailable Pyrazolopiperazine BACE1..:

Peschiulli, Aldo ; Oehlrich, Daniel ; Van Gool, Michiel...
ACS Medicinal Chemistry Letters. 13 (2021) 1 - p. 76-83 , 2021

Link: https://doi.org/10.1021/..

2

[1,2,4]Triazolo[1,5-a]pyrimidine Phosphodiesterase 2A Inhib..:

Tresadern, Gary ; Velter, Ingrid ; Trabanco, Andrés A....
Journal of Medicinal Chemistry. 63 (2020) 21 - p. 12887-12910 , 2020

Link: https://doi.org/10.1021/..

3

Design and synthesis of a novel series of cyanoindole deriv..:

Bischoff, François P. ; Velter, Adriana Ingrid ; Minne, Garrett...
Bioorganic & Medicinal Chemistry Letters. 29 (2019) 14 - p. 1737-1745 , 2019

Link: https://doi.org/10.1016/..

4

Evaluation of a Series of β-Secretase 1 Inhibitors Containi..:

Oehlrich, Daniel ; Peschiulli, Aldo ; Tresadern, Gary...
ACS Medicinal Chemistry Letters. 10 (2019) 8 - p. 1159-1165 , 2019

Link: https://doi.org/10.1021/..

5

Correction to Optimization of 1,4-Oxazine β-Secretase 1 (BA..:

Gijsen, Harrie J. M. ; Alonso de Diego, Sergio A. ; De Cleyn, Michel...
Journal of Medicinal Chemistry. 61 (2018) 24 - p. 11415-11415 , 2018

Link: https://doi.org/10.1021/..

6

Optimization of 1,4-Oxazine β-Secretase 1 (BACE1) Inhibitor..:

Gijsen, Harrie J. M. ; Alonso de Diego, Sergio A. ; De Cleyn, Michel...
Journal of Medicinal Chemistry. 61 (2018) 12 - p. 5292-5303 , 2018

Link: https://doi.org/10.1021/..

7

1,3,5-Trisubstituted Pyrazoles as Potent Negative Allosteri..:

Van Gool, Michiel ; Alonso De Diego, Sergio A. ; Delgado, Oscar...
ChemMedChem. 12 (2017) 12 - p. 905-912 , 2017

Link: https://doi.org/10.1002/..

8

Discovery of N-(Pyridin-4-yl)-1,5-naphthyridin-2-amines as ..:

Rombouts, Frederik J. R. ; Andrés, José-Ignacio ; Ariza, Manuela...
Journal of Medicinal Chemistry. 60 (2017) 4 - p. 1272-1291 , 2017

Link: https://doi.org/10.1021/..

9

Industrial medicinal chemistry insights: neuroscience hit g..:

Tresadern, Gary ; Rombouts, Frederik J.R. ; Oehlrich, Daniel..
Drug Discovery Today. 22 (2017) 10 - p. 1478-1488 , 2017

Link: https://doi.org/10.1016/..

10

Preliminary investigation of 6,7-dihydropyrazolo[1,5- a ]py..:

Conde-Ceide, Susana ; Alcázar, Jesús ; Alonso de Diego, Sergio A....
Bioorganic & Medicinal Chemistry Letters. 26 (2016) 2 - p. 429-434 , 2016

Link: https://doi.org/10.1016/..

11

Discovery of 8-Trifluoromethyl-3-cyclopropylmethyl-7-[(4-(2..:

Cid, Jose María ; Tresadern, Gary ; Vega, Juan Antonio...
Journal of Medicinal Chemistry. 59 (2016) 18 - p. 8495-8507 , 2016

Link: https://doi.org/10.1021/..

12

Energy: Oilman at the peak:

Macdonald, Gregor
Nature. 532 (2016) 7597 - p. 31-32 , 2016

Link: https://doi.org/10.1038/..

13

Biased mGlu 5 -Positive Allosteric Modulators Provide In Vi..:

Rook, Jerri M. ; Xiang, Zixiu ; Lv, Xiaohui...
Neuron. 86 (2015) 4 - p. 1029-1040 , 2015

Link: https://doi.org/10.1016/..

14

Discovery of VU0409551/JNJ-46778212: An mGlu5 Positive Allo..:

Conde-Ceide, Susana ; Martínez-Viturro, Carlos M. ; Alcázar, Jesús...
ACS Medicinal Chemistry Letters. 6 (2015) 6 - p. 716-720 , 2015

Link: https://doi.org/10.1021/..

15

Further optimization of the mGlu5 PAM clinical candidate VU..:

Zhou, Ya ; Malosh, Chrysa ; Conde-Ceide, Susana...
Bioorganic & Medicinal Chemistry Letters. 25 (2015) 17 - p. 3515-3519 , 2015

Link: https://doi.org/10.1016/..