E-LIB Suche - Ergebnisse für: Martinez-Alsina, Luis

1

Pinnick Oxidation on Scale: Process Development of a BDK In..:

Arcari, Joel T. ; Buckley, Catherine ; Buzon, Leanne M....
Organic Process Research & Development. , 2024

2

Discovery of the Potent and Selective MC4R Antagonist PF-07..:

Garnsey, Michelle R. ; Smith, Aaron C. ; Polivkova, Jana...
Journal of Medicinal Chemistry. 66 (2023) 5 - p. 3195-3211 , 2023

Link: https://doi.org/10.1021/..

3

Design and Synthesis of Clinical Candidate PF-06751979: A P..:

O'Neill, Brian T. ; Beck, Elizabeth M. ; Butler, Christopher R....
Journal of Medicinal Chemistry. 61 (2018) 10 - p. 4476-4504 , 2018

Link: https://doi.org/10.1021/..

4

Spiropiperidine Sultam and Lactam Templates: Diastereoselec..:

Martinez-Alsina, Luis A. ; Murray, John C. ; Buzon, Leanne M....
The Journal of Organic Chemistry. 82 (2017) 23 - p. 12246-12256 , 2017

Link: https://doi.org/10.1021/..

5

Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Enga..:

Butler, Christopher R. ; Ogilvie, Kevin ; Martinez-Alsina, Luis...
Journal of Medicinal Chemistry. 60 (2016) 1 - p. 386-402 , 2016

Link: https://doi.org/10.1021/..

6

Discovery of a Series of Efficient, Centrally Efficacious B..:

Butler, Christopher R. ; Brodney, Michael A. ; Beck, Elizabeth M....
Journal of Medicinal Chemistry. 58 (2015) 6 - p. 2678-2702 , 2015

Link: https://doi.org/10.1021/..

7

Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduc..:

Brodney, Michael A. ; Beck, Elizabeth M. ; Butler, Christopher R....
Journal of Medicinal Chemistry. 58 (2015) 7 - p. 3223-3252 , 2015

Link: https://doi.org/10.1021/..

8

Discovery of PF-04449913, a Potent and Orally Bioavailable ..:

Munchhof, Michael J. ; Li, Qifang ; Shavnya, Andrei...
ACS Medicinal Chemistry Letters. 3 (2011) 2 - p. 106-111 , 2011

Link: https://doi.org/10.1021/..

9

P3‐282: β‐secretase inhibitors for treatment of Alzheimer's..:

O'Neill, Brian T. ; Brodney, Michael A. ; Ambroise, Claude...
Alzheimer's & Dementia. 6 (2010) 4S_Part_17 - p. , 2010

Link: https://doi.org/10.1016/..

10

A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor..:

Allerton, Charlotte M. N. ; Arcari, Joel T. ; Aschenbrenner, Lisa M....
Journal of Medicinal Chemistry. , 2024

Link: https://doi.org/10.1021/..

11

Small molecule branched-chain ketoacid dehydrogenase kinase..:

Roth Flach, Rachel J. ; Bollinger, Eliza ; Reyes, Allan R....
Nature Communications. 14 (2023) 1 - p. , 2023

Link: https://doi.org/10.1038/..

12

Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Enga..:

Butler, Christopher R ; Ogilvie, Kevin ; Martinez-Alsina, Luis...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461923/. , 2016

Link: http://www.ncbi.nlm.nih...

13

Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduc..:

Brodney, Michael A ; Beck, Elizabeth M ; Butler, Christopher R...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415909/. , 2015

Link: http://www.ncbi.nlm.nih...

14

Discovery of PF-04449913, a Potent and Orally Bioavailable ..:

Munchhof, Michael J ; Li, Qifang ; Shavnya, Andrei...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC. , 2011

Link: http://www.ncbi.nlm.nih...

15

Synthesis of Small 3-Fluoro- and 3,3-Difluoropyrrolidines U..:

McAlpine, Indrawan ; Tran-Dubé, Michelle ; Wang, Fen...
The Journal of Organic Chemistry. 80 (2015) 14 - p. 7266-7274 , 2015

Link: https://doi.org/10.1021/..