E-LIB Suche - Ergebnisse für: McHardy, Tatiana

1

Discovery of 2-(3-Benzamidopropanamido)thiazole-5-carboxyla..:

Saint-Dizier, François ; Matthews, Thomas P. ; Gregson, Aaron M....
Journal of Medicinal Chemistry. 66 (2023) 4 - p. 2622-2645 , 2023

Link: https://doi.org/10.1021/..

2

Binding to an Unusual Inactive Kinase Conformation by Highl..:

Colombano, Giampiero ; Caldwell, John J. ; Matthews, Thomas P....
Journal of Medicinal Chemistry. 62 (2019) 5 - p. 2447-2465 , 2019

Link: https://doi.org/10.1021/..

3

Multiparameter Lead Optimization to Give an Oral Checkpoint..:

Osborne, James D. ; Matthews, Thomas P. ; McHardy, Tatiana...
Journal of Medicinal Chemistry. 59 (2016) 11 - p. 5221-5237 , 2016

Link: https://doi.org/10.1021/..

4

The clinical development candidate CCT245737 is an orally a..:

Walton, Mike I. ; Eve, Paul D. ; Hayes, Angela...
Oncotarget. 7 (2015) 3 - p. 2329-2342 , 2015

Link: https://doi.org/10.18632..

5

Molecular mechanisms of human IRE1 activation through dimer..:

Joshi, Amar ; Newbatt, Yvette ; McAndrew, P. Craig...
Oncotarget. 6 (2015) 15 - p. 13019-13035 , 2015

Link: https://doi.org/10.18632..

6

Discovery of 3-Alkoxyamino-5-(pyridin-2-ylamino)pyrazine-2-..:

Lainchbury, Michael ; Matthews, Thomas P. ; McHardy, Tatiana...
Journal of Medicinal Chemistry. 55 (2012) 22 - p. 10229-10240 , 2012

Link: https://doi.org/10.1021/..

7

Discovery of 4-Amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pip..:

McHardy, Tatiana ; Caldwell, John J. ; Cheung, Kwai-Ming...
Journal of Medicinal Chemistry. 53 (2010) 5 - p. 2239-2249 , 2010

Link: https://doi.org/10.1021/..

8

Design and evaluation of 3,6-di(hetero)aryl imidazo[1,2-a]p..:

Matthews, Thomas P. ; McHardy, Tatiana ; Klair, Suki...
Bioorganic & Medicinal Chemistry Letters. 20 (2010) 14 - p. 4045-4049 , 2010

Link: https://doi.org/10.1016/..

9

Identification of Inhibitors of Checkpoint Kinase 1 through..:

Matthews, Thomas P. ; Klair, Suki ; Burns, Samantha...
Journal of Medicinal Chemistry. 52 (2009) 15 - p. 4810-4819 , 2009

Link: https://doi.org/10.1021/..

10

Identification of 4-(4-Aminopiperidin-1-yl)-7H-pyrrolo[2,3-..:

Caldwell, John J. ; Davies, Thomas G. ; Donald, Alastair...
Journal of Medicinal Chemistry. 51 (2008) 7 - p. 2147-2157 , 2008

Link: https://doi.org/10.1021/..

11

Rapid Evolution of 6-Phenylpurine Inhibitors of Protein Kin..:

Donald, Alastair ; McHardy, Tatiana ; Rowlands, Martin G....
Journal of Medicinal Chemistry. 50 (2007) 10 - p. 2289-2292 , 2007

Link: https://doi.org/10.1021/..

12

A Structural Comparison of Inhibitor Binding to PKB, PKA an..:

Davies, Thomas G. ; Verdonk, Marcel L. ; Graham, Brent...
Journal of Molecular Biology. 367 (2007) 3 - p. 882-894 , 2007

Link: https://doi.org/10.1016/..

13

Discovery of 2-(3-Benzamidopropanamido)thiazole-5-carboxyla..:

Saint-Dizier, François ; Matthews, Thomas P ; Gregson, Aaron M...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969401/. , 2023

Link: http://www.ncbi.nlm.nih...

14

Discovery of 3-Alkoxyamino-5-(pyridin-2-ylamino)pyrazine-2-..:

Lainchbury, Michael ; Matthews, Thomas P ; McHardy, Tatiana...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506129. , 2012

Link: http://www.ncbi.nlm.nih...

15

Discovery of 4-Amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pip..:

McHardy, Tatiana ; Caldwell, John J ; Cheung, Kwai-Ming...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832868. , 2010

Link: http://www.ncbi.nlm.nih...