E-LIB Suche - Ergebnisse für: McKinney, David C.

1

Discovery of a First-in-Class Inhibitor of the PRMT5–Substr..:

McKinney, David C. ; McMillan, Brian J. ; Ranaghan, Matthew J....
Journal of Medicinal Chemistry. 64 (2021) 15 - p. 11148-11168 , 2021

Link: https://doi.org/10.1021/..

2

Antibacterial FabH Inhibitors with Mode of Action Validated..:

McKinney, David C. ; Eyermann, Charles J. ; Gu, Rong-Fang...
ACS Infectious Diseases. 2 (2016) 7 - p. 456-464 , 2016

Link: https://doi.org/10.1021/..

3

Structural Insights Lead to a Negamycin Analogue with Impro..:

McKinney, David C. ; Basarab, Gregory S. ; Cocozaki, Alexis I....
ACS Medicinal Chemistry Letters. 6 (2015) 8 - p. 930-935 , 2015

Link: https://doi.org/10.1021/..

4

4,5-Disubstituted 6-Aryloxy-1,3-dihydrobenzo[c][1,2]oxaboro..:

McKinney, David C. ; Zhou, Fei ; Eyermann, Charles J....
ACS Infectious Diseases. 1 (2015) 7 - p. 310-316 , 2015

Link: https://doi.org/10.1021/..

5

Novel broad-spectrum inhibitors of bacterial methionine ami..:

Rose, Jonathan A. ; Lahiri, Sushmita D. ; McKinney, David C....
Bioorganic & Medicinal Chemistry Letters. 25 (2015) 16 - p. 3301-3306 , 2015

Link: https://doi.org/10.1016/..

6

X-ray Crystal Structures of Escherichia coli RNA Polymerase..:

Molodtsov, Vadim ; Fleming, Paul R. ; Eyermann, Charles J....
Journal of Medicinal Chemistry. 58 (2015) 7 - p. 3156-3171 , 2015

Link: https://doi.org/10.1021/..

7

Illicit Transport via Dipeptide Transporter Dpp is Irreleva..:

McKinney, David C. ; Bezdenejnih-Snyder, Natascha ; Farrington, Krista...
ACS Infectious Diseases. 1 (2015) 5 - p. 222-230 , 2015

Link: https://doi.org/10.1021/..

8

The Role of a Novel Auxiliary Pocket in Bacterial Phenylala..:

Abibi, Ayome ; Ferguson, Andrew D. ; Fleming, Paul R....
Journal of Biological Chemistry. 289 (2014) 31 - p. 21651-21662 , 2014

Link: https://doi.org/10.1074/..

9

Pyrazolopyrimidines Establish MurC as a Vulnerable Target i..:

Hameed P, Shahul ; Manjrekar, Praveena ; Chinnapattu, Murugan...
ACS Chemical Biology. 9 (2014) 10 - p. 2274-2282 , 2014

Link: https://doi.org/10.1021/..

10

Selective Inhibitors of Bacterial t-RNA-(N1G37) Methyltrans..:

Hill, Pamela J. ; Abibi, Ayome ; Albert, Robert...
Journal of Medicinal Chemistry. 56 (2013) 18 - p. 7278-7288 , 2013

Link: https://doi.org/10.1021/..

11

Time-dependent, reversible, oxaborole inhibition of Escheri..:

Shapiro, Adam B. ; Gao, Ning ; Hajec, Laurel.
Analytical Biochemistry. 431 (2012) 1 - p. 48-53 , 2012

Link: https://doi.org/10.1016/..

12

Synthesis of Amine- and Thiol-Modified Nucleoside Phosphora..:

Jin, Shengxi ; Miduturu, Chandrasekhar V. ; McKinney, David C..
The Journal of Organic Chemistry. 70 (2005) 11 - p. 4284-4299 , 2005

Link: https://doi.org/10.1021/..

13

Discovery of a first-in-class inhibitor of the PRMT5-substr..:

McKinney, David C ; McMillan, Brian J ; Ranaghan, Matthew J...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036822/. , 2021

Link: http://www.ncbi.nlm.nih...

14

Molecular basis for substrate recruitment to the PRMT5 meth..:

Mulvaney, Kathleen M ; Blomquist, Christa ; Acharya, Nischal...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016627/. , 2021

Link: http://www.ncbi.nlm.nih...

15

X-ray crystal structures of Escherichia coli RNA polymerase..:

Molodtsov, Vadim ; Fleming, Paul R ; Eyermann, Charles J...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658208/. , 2015

Link: http://www.ncbi.nlm.nih...