E-LIB Suche - Ergebnisse für: Nagasawa, Johnny

1

P153 MET642, AN ORAL FXR AGONIST, IMPROVES COLITIS INDUCED ..:

Liu, Xueqing ; O'Connell, Robert ; Bendele, Alison...
Gastroenterology. 158 (2020) 3 - p. S11 , 2020

Link: https://doi.org/10.1053/..

2

767 ACTIVATION OF FXR SUPPRESSES TNFA AND IL-6 SIGNALING PA..:

Liu, Xueqing ; O'Connell, Robert ; Bendele, Alison...
Gastroenterology. 158 (2020) 6 - p. S-159-S-160 , 2020

Link: https://doi.org/10.1016/..

3

P153 MET642, AN ORAL FXR AGONIST, IMPROVES COLITIS INDUCED ..:

Liu, Xueqing ; O'Connell, Robert ; Bendele, Alison...
Inflammatory Bowel Diseases. 26 (2020) Supplement_1 - p. S6-S7 , 2020

Link: https://doi.org/10.1093/..

4

Sa1747 – Fxr Agonists with Sustained Activity Exhibit Effic..:

Liu, Xueqing ; Dedman, Harry ; O'Connell, Robert...
Gastroenterology. 156 (2019) 6 - p. S-385 , 2019

Link: https://doi.org/10.1016/..

5

Sa1737 – Fxr Agonist M480, Exhibits Efficacy in Multiple Mo..:

Liu, Xueqing ; Dedman, Harry ; O'Connell, Robert...
Gastroenterology. 156 (2019) 6 - p. S-382 , 2019

Link: https://doi.org/10.1016/..

6

1051 - M480, an Oral Fxr Agonist, is Superior to Cyclospori..:

Liu, Xueqing ; Dedman, Harry ; O'Connell, Robert...
Gastroenterology. 154 (2018) 6 - p. S-198-S-199 , 2018

Link: https://doi.org/10.1016/..

7

Identification of an Orally Bioavailable Chromene-Based Sel..:

Nagasawa, Johnny ; Govek, Steven ; Kahraman, Mehmet...
Journal of Medicinal Chemistry. 61 (2018) 17 - p. 7917-7928 , 2018

Link: https://doi.org/10.1021/..

8

Identification of GDC-0810 (ARN-810), an Orally Bioavailabl..:

Lai, Andiliy ; Kahraman, Mehmet ; Govek, Steven...
Journal of Medicinal Chemistry. 58 (2015) 12 - p. 4888-4904 , 2015

Link: https://doi.org/10.1021/..

9

Discovery of CX-5461, the First Direct and Selective Inhibi..:

Haddach, Mustapha ; Schwaebe, Michael K. ; Michaux, Jerome...
ACS Medicinal Chemistry Letters. 3 (2012) 7 - p. 602-606 , 2012

Link: https://doi.org/10.1021/..

10

Pre-clinical characterization of CX-4945, a potent and sele..:

Pierre, Fabrice ; Chua, Peter C. ; O'Brien, Sean E....
Molecular and Cellular Biochemistry. 356 (2011) 1-2 - p. 37-43 , 2011

Link: https://doi.org/10.1007/..

11

Discovery and SAR of 5-(3-Chlorophenylamino)benzo[c][2,6]na..:

Pierre, Fabrice ; Chua, Peter C. ; O'Brien, Sean E....
Journal of Medicinal Chemistry. 54 (2010) 2 - p. 635-654 , 2010

Link: https://doi.org/10.1021/..

12

The design and synthesis of potent and cell-active alloster..:

Siu, Tony ; Li, Yiwei ; Nagasawa, Johnny...
Bioorganic & Medicinal Chemistry Letters. 18 (2008) 14 - p. 4191-4194 , 2008

Link: https://doi.org/10.1016/..

13

Correction: The selective estrogen receptor downregulator G..:

Joseph, James D ; Darimont, Beatrice ; Zhou, Wei...
eLife. 8 (2019) - p. , 2019

Link: https://doi.org/10.7554/..

14

Selective estrogen receptor degraders with novel structural..:

Govek, Steven P. ; Bonnefous, Celine ; Julien, Jackaline D....
Bioorganic & Medicinal Chemistry Letters. 29 (2019) 3 - p. 367-372 , 2019

Link: https://doi.org/10.1016/..

15

Maximizing ER-α Degradation Maximizes Activity in a Tamoxif..:

Kahraman, Mehmet ; Govek, Steven P. ; Nagasawa, Johnny Y....
ACS Medicinal Chemistry Letters. 10 (2018) 1 - p. 50-55 , 2018

Link: https://doi.org/10.1021/..