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Nwachukwu, Jerome C
387  Ergebnisse:
Personensuche X
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1

Asymmetric allostery in estrogen receptor-α homodimers driv..:

Min, Charles K. ; Nwachukwu, Jerome C. ; Hou, Yingwei...
Proceedings of the National Academy of Sciences.  121 (2024)  24 - p. , 2024
Link: https://doi.org/10.1073/..
 
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2

OR11-01 A New Model for Estrogen Receptor-alpha Antagonist ..:

Nwachukwu, Jerome C ; Njeri, Jacqline W ; Venables, Thomas...
Journal of the Endocrine Society.  7 (2023)  Supplement_1 - p. , 2023
Link: https://doi.org/10.1210/..
 
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3

Design, synthesis, biological evaluation and crystal struct..:

Tinivella, Annachiara ; Nwachukwu, Jerome C. ; Angeli, Andrea...
European Journal of Medicinal Chemistry.  246 (2023)  - p. 115011 , 2023
Link: https://doi.org/10.1016/..
 
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4

Activation of Crtc2/Creb1 in skeletal muscle enhances weigh..:

Bruno, Nelson E. ; Nwachukwu, Jerome C. ; Hughes, David C....
The FASEB Journal.  35 (2021)  12 - p. , 2021
Link: https://doi.org/10.1096/..
 
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5

Dual-mechanism estrogen receptor inhibitors:

Min, Jian ; Nwachukwu, Jerome C. ; Min, Charles K....
Proceedings of the National Academy of Sciences.  118 (2021)  35 - p. , 2021
Link: https://doi.org/10.1073/..
 
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6

Chemical systems biology reveals mechanisms of glucocortico..:

Bruno, Nelson E. ; Nwachukwu, Jerome C. ; Srinivasan, Sathish...
Nature Chemical Biology.  17 (2021)  3 - p. 307-316 , 2021
Link: https://doi.org/10.1038/..
 
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7

Unexpected equivalent potency of a constrained chromene ena..:

Zhang, Birong ; Kiefer, James R. ; Blake, Robert A....
Bioorganic & Medicinal Chemistry Letters.  29 (2019)  7 - p. 905-911 , 2019
Link: https://doi.org/10.1016/..
 
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8

Cryptic glucocorticoid receptor-binding sites pervade genom..:

Hudson, William H. ; Vera, Ian Mitchelle S. de ; Nwachukwu, Jerome C....
Nature Communications.  9 (2018)  1 - p. , 2018
Link: https://doi.org/10.1038/..
 
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9

The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overco..:

Fanning, Sean W ; Jeselsohn, Rinath ; Dharmarajan, Venkatasubramanian...
eLife.  7 (2018)  - p. , 2018
Link: https://doi.org/10.7554/..
 
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10

Tethering not required: the glucocorticoid receptor binds d..:

Weikum, Emily R. ; de Vera, Ian Mitchelle S. ; Nwachukwu, Jerome C....
Nucleic Acids Research.  45 (2017)  14 - p. 8596-8608 , 2017
Link: https://doi.org/10.1093/..
 
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11

Synthesis of novel steroidal agonists, partial agonists, an..:

Jin, Zhuang ; Lin, Hua ; Srinivasan, Sathish...
Bioorganic & Medicinal Chemistry Letters.  27 (2017)  2 - p. 347-353 , 2017
Link: https://doi.org/10.1016/..
 
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12

Exploring the Structural Compliancy versus Specificity of t..:

Sharma, Naina ; Carlson, Kathryn E. ; Nwachukwu, Jerome C....
ACS Chemical Biology.  12 (2016)  2 - p. 494-503 , 2016
Link: https://doi.org/10.1021/..
 
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13

Predictive features of ligand‐specific signaling through th..:

Nwachukwu, Jerome C ; Srinivasan, Sathish ; Zheng, Yangfan...
Molecular Systems Biology.  12 (2016)  4 - p. , 2016
Link: https://doi.org/10.15252..
 
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14

Structural mechanism for signal transduction in RXR nuclear..:

Kojetin, Douglas J. ; Matta-Camacho, Edna ; Hughes, Travis S....
Nature Communications.  6 (2015)  1 - p. , 2015
Link: https://doi.org/10.1038/..
 
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15

Resveratrol modulates the inflammatory response via an estr..:

Nwachukwu, Jerome C ; Srinivasan, Sathish ; Bruno, Nelson E...
eLife.  3 (2014)  - p. , 2014
Link: https://doi.org/10.7554/..
 
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