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O'Brien, Edward P.
7647  Ergebnisse:
Personensuche X
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1

Binding small-molecule drugs may avoid protein misfolding i..:

Jiang, Yang ; O'Brien, Edward P.
Biophysical Journal.  123 (2024)  3 - p. 185a , 2024
Link: https://doi.org/10.1016/..
 
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2

Non-covalent Lasso Entanglements in Folded Proteins: Preval..:

Rana, Viraj ; Sitarik, Ian ; Petucci, Justin...
Journal of Molecular Biology.  436 (2024)  6 - p. 168459 , 2024
Link: https://doi.org/10.1016/..
 
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3

A newly predicted class of protein misfolding explains deca..:

O'Brien, Edward P.
Biophysical Journal.  123 (2024)  3 - p. 300a , 2024
Link: https://doi.org/10.1016/..
 
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4

Synonymous Mutations Can Alter Protein Dimerization Through..:

Lan, Pham Dang ; Nissley, Daniel Allen ; Sitarik, Ian...
Journal of Molecular Biology.  436 (2024)  6 - p. 168487 , 2024
Link: https://doi.org/10.1016/..
 
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5

Native entanglement misfolding can cause a loss-of-function..:

Sitarik, Ian M. ; O'Brien, Edward P.
Biophysical Journal.  123 (2024)  3 - p. 446a-447a , 2024
Link: https://doi.org/10.1016/..
 
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6

Deciphering the free energy landscapes of SARS-CoV-2 wild t..:

Lan, Pham Dang ; Nissley, Daniel A. ; O'Brien, Edward P...
The Journal of Chemical Physics.  160 (2024)  5 - p. , 2024
Link: https://doi.org/10.1063/..
 
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7

It is theoretically possible to avoid misfolding into non-c..:

Jiang, Yang ; Deane, Charlotte M. ; Morris, Garrett M...
PLOS Computational Biology.  20 (2024)  3 - p. e1011901 , 2024
Link: https://doi.org/10.1371/..
 
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8

Incorporating mutational heterogeneity to identify genes th..:

Rao, Yiyun ; Ahmed, Nabeel ; Pritchard, Justin.
BMC Bioinformatics.  24 (2023)  1 - p. , 2023
Link: https://doi.org/10.1186/..
 
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9

How soluble misfolded proteins bypass chaperones at the mol..:

Halder, Ritaban ; Nissley, Daniel A. ; Sitarik, Ian...
Nature Communications.  14 (2023)  1 - p. , 2023
Link: https://doi.org/10.1038/..
 
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10

Is Posttranslational Folding More Efficient Than Refolding ..:

Vu, Quyen V. ; Nissley, Daniel A. ; Jiang, Yang..
The Journal of Physical Chemistry B.  127 (2023)  21 - p. 4761-4774 , 2023
Link: https://doi.org/10.1021/..
 
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11

Modeling Ensembles of Enzyme Reaction Pathways with Hi-MSM ..:

Persichetti, Joseph R. ; Jiang, Yang ; Hudson, Phillip S..
The Journal of Physical Chemistry B.  126 (2022)  47 - p. 9748-9758 , 2022
Link: https://doi.org/10.1021/..
 
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12

Correction to "Ribosome Elongation Kinetics of Consecutivel..:

Leininger, Sarah E. ; Rodriguez, Judith ; Vu, Quyen V....
Biochemistry.  61 (2022)  2 - p. 125-125 , 2022
Link: https://doi.org/10.1021/..
 
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13

How synonymous mutations alter enzyme structure and functio..:

Jiang, Yang ; Neti, Syam Sundar ; Sitarik, Ian...
Nature Chemistry.  15 (2022)  3 - p. 308-318 , 2022
Link: https://doi.org/10.1038/..
 
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14

Pulse labeling reveals the tail end of protein folding by p..:

Zhu, Mang ; Kuechler, Erich R. ; Wong, Ryan W.K....
Cell Reports.  40 (2022)  3 - p. 111096 , 2022
Link: https://doi.org/10.1016/..
 
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15

A pan-CRISPR analysis of mammalian cell specificity identif..:

Zhao, Boyang ; Rao, Yiyun ; Leighow, Scott...
Nature Communications.  13 (2022)  1 - p. , 2022
Link: https://doi.org/10.1038/..
 
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