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1
Complete biological dataset:
Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/dataset/Complete_biological_dataset_/14078722. , 2021
https://figshare.com/articles/dataset/Complete_biological_dataset_/14078722. , 2021
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2
Chemical structure, initial hit assessment data and metabol..:
Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/Chemical_structure_initial_hit_assessment_data_and_metabolic_soft_spots_for_compound_1_/14078728. , 2021
https://figshare.com/articles/figure/Chemical_structure_initial_hit_assessment_data_and_metabolic_soft_spots_for_compound_1_/14078728. , 2021
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3
Proof of concept in vivo activity in a VL acute model:
Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/Proof_of_concept_in_vivo_activity_in_a_VL_acute_model_/14078755. , 2021
https://figshare.com/articles/figure/Proof_of_concept_in_vivo_activity_in_a_VL_acute_model_/14078755. , 2021
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4
In vitro profiling of analogues with modifications at the N..:
Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/In_vitro_profiling_of_analogues_with_modifications_at_the_N-alkyl_chain_/14078740. , 2021
https://figshare.com/articles/figure/In_vitro_profiling_of_analogues_with_modifications_at_the_N-alkyl_chain_/14078740. , 2021
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5
Summary of SARs and SPRs for 2-aminobenzimidazole derivativ..:
Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/Summary_of_SARs_and_SPRs_for_2-aminobenzimidazole_derivatives_/14078752. , 2021
https://figshare.com/articles/figure/Summary_of_SARs_and_SPRs_for_2-aminobenzimidazole_derivatives_/14078752. , 2021
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6
In vitro profiling of analogues with additional modificatio..:
Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/In_vitro_profiling_of_analogues_with_additional_modifications_at_the_benzimidazole_core_and_side_chain_/14078746. , 2021
https://figshare.com/articles/figure/In_vitro_profiling_of_analogues_with_additional_modifications_at_the_benzimidazole_core_and_side_chain_/14078746. , 2021
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7
Synthesis of purine 56:
Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/Synthesis_of_purine_56_/14078734. , 2021
https://figshare.com/articles/figure/Synthesis_of_purine_56_/14078734. , 2021
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8
Detailed synthetic and spectral information:
Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/journal_contribution/Detailed_synthetic_and_spectral_information_/14078725. , 2021
https://figshare.com/articles/journal_contribution/Detailed_synthetic_and_spectral_information_/14078725. , 2021
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9
In vitro profiling of analogues with modifications in the b..:
Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/In_vitro_profiling_of_analogues_with_modifications_in_the_benzimidazole_ring_/14078737. , 2021
https://figshare.com/articles/figure/In_vitro_profiling_of_analogues_with_modifications_in_the_benzimidazole_ring_/14078737. , 2021
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10
Synthesis of 2-aminobenzimidazoles:
Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/Synthesis_of_2-aminobenzimidazoles_/14078731. , 2021
https://figshare.com/articles/figure/Synthesis_of_2-aminobenzimidazoles_/14078731. , 2021
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11
Summary of in vitro ADME and in vivo PK data for selected c..:
Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/dataset/Summary_of_in_vitro_ADME_and_in_vivo_PK_data_for_selected_compounds_/14078758. , 2021
https://figshare.com/articles/dataset/Summary_of_in_vitro_ADME_and_in_vivo_PK_data_for_selected_compounds_/14078758. , 2021
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12
In vitro profiling of analogues with modifications at the a..:
Rafael Augusto Alves Ferreira (10178749) ; Celso de Oliveira Rezende Junior (8114732) ; Pablo David Grigol Martinez (10178752)...
https://figshare.com/articles/figure/In_vitro_profiling_of_analogues_with_modifications_at_the_amide_group_/14078743. , 2021
https://figshare.com/articles/figure/In_vitro_profiling_of_analogues_with_modifications_at_the_amide_group_/14078743. , 2021