E-LIB Suche - Ergebnisse für: Randolph, John T.

1

Correction to "Discovery of ABBV-3373, an Anti-TNF Glucocor..:

Hobson, Adrian D. ; McPherson, Michael J. ; Hayes, Martin E....
Journal of Medicinal Chemistry. 66 (2023) 8 - p. 6010-6010 , 2023

Link: https://doi.org/10.1021/..

2

Discovery of a Potent Chloroacetamide GPX4 Inhibitor with B..:

Randolph, John T. ; O'Connor, Matthew J. ; Han, Fei...
Journal of Medicinal Chemistry. 66 (2023) 6 - p. 3852-3865 , 2023

Link: https://doi.org/10.1021/..

3

Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor..:

Hobson, Adrian D. ; McPherson, Michael J. ; Hayes, Martin E....
Journal of Medicinal Chemistry. 65 (2022) 23 - p. 15893-15934 , 2022

Link: https://doi.org/10.1021/..

4

Desymmetrization of pibrentasvir for efficient prodrug synt..:

Voight, Eric A. ; Greszler, Stephen N. ; Hartung, John...
Chemical Science. 12 (2021) 29 - p. 10076-10082 , 2021

Link: https://doi.org/10.1039/..

5

Synthesis and evaluation of 2′-dihalo ribonucleotide prodru..:

Chris Krueger, A. ; Chen, Hui-Ju ; Randolph, John T....
Bioorganic & Medicinal Chemistry. 28 (2020) 1 - p. 115208 , 2020

Link: https://doi.org/10.1016/..

6

Discovery of 2-aminoisobutyric acid ethyl ester (AIBEE) pho..:

Randolph, John T. ; Li, Tongmei ; Chris Krueger, A....
Bioorganic & Medicinal Chemistry Letters. 30 (2020) 7 - p. 126986 , 2020

Link: https://doi.org/10.1016/..

7

Prodrug Strategies to Improve the Solubility of the HCV NS5..:

Randolph, John T. ; Voight, Eric A. ; Greszler, Stephen N....
Journal of Medicinal Chemistry. 63 (2020) 19 - p. 11034-11044 , 2020

Link: https://doi.org/10.1021/..

8

HCV NS5A as an Antiviral Therapeutic Target: From Validatio..:

, In: Topics in Medicinal Chemistry; HCV: The Journey from Discovery to a Cure,

Wagner, Rolf ; DeGoey, David A. ; Randolph, John T.... - p. 133-156 , 2019

Link: https://doi.org/10.1007/..

9

Synthesis and Biological Characterization of Aryl Uracil In..:

Randolph, John T. ; Krueger, A. Chris ; Donner, Pamela L....
Journal of Medicinal Chemistry. 61 (2018) 3 - p. 1153-1163 , 2018

Link: https://doi.org/10.1021/..

10

Highlights of the Structure–Activity Relationships of Benzi..:

Wagner, Rolf ; Randolph, John T. ; Patel, Sachin V....
Journal of Medicinal Chemistry. 61 (2018) 9 - p. 4052-4066 , 2018

Link: https://doi.org/10.1021/..

11

In VitroAntiviral Activity and Resistance Profile of the Ne..:

Ng, Teresa I. ; Krishnan, Preethi ; Pilot-Matias, Tami...
Antimicrobial Agents and Chemotherapy. 61 (2017) 5 - p. , 2017

Link: https://doi.org/10.1128/..

12

Discovery of fluorobenzimidazole HCV NS5A inhibitors:

Randolph, John T. ; Flentge, Charles A. ; Donner, Pamela...
Bioorganic & Medicinal Chemistry Letters. 26 (2016) 22 - p. 5462-5467 , 2016

Link: https://doi.org/10.1016/..

13

Discovery of ABT-267, a Pan-Genotypic Inhibitor of HCV NS5A:

DeGoey, David A. ; Randolph, John T. ; Liu, Dachun...
Journal of Medicinal Chemistry. 57 (2014) 5 - p. 2047-2057 , 2014

Link: https://doi.org/10.1021/..

14

High potency improvements to weak aryl uracil HCV polymeras..:

Donner, Pamela ; Randolph, John T. ; Huang, Peggy...
Bioorganic & Medicinal Chemistry Letters. 23 (2013) 15 - p. 4367-4369 , 2013

Link: https://doi.org/10.1016/..

15

Aryl uracil inhibitors of hepatitis C virus NS5B polymerase..:

Krueger, A. Chris ; Randolph, John T. ; DeGoey, David A....
Bioorganic & Medicinal Chemistry Letters. 23 (2013) 12 - p. 3487-3490 , 2013

Link: https://doi.org/10.1016/..