E-LIB Suche - Ergebnisse für: Rawlins, Philip B

1

Design of rigid protein–protein interaction inhibitors enab..:

Hargreaves, David ; Carbajo, Rodrigo J. ; Bodnarchuk, Michael S....
Proceedings of the National Academy of Sciences. 120 (2023) 21 - p. , 2023

Link: https://doi.org/10.1073/..

2

Design and Evaluation of a Low Hydrogen Bond Donor Count Fr..:

Whitehurst, Benjamin C. ; Bauer, Matthias R. ; Edfeldt, Fredrik...
Journal of Medicinal Chemistry. 66 (2023) 11 - p. 7594-7604 , 2023

Link: https://doi.org/10.1021/..

3

Pharmacological inhibition of MERTK induces in vivo retinal..:

Hamm, Gregory ; Maglennon, Gareth ; Williamson, Beth...
Archives of Toxicology. 96 (2022) 2 - p. 613-624 , 2022

Link: https://doi.org/10.1007/..

4

Surface Plasmon Resonance Screening to Identify Active and ..:

Shepherd, Claire ; Robinson, Sean ; Berizzi, Alice...
ACS Medicinal Chemistry Letters. 13 (2022) 7 - p. 1172-1181 , 2022

Link: https://doi.org/10.1021/..

5

Fragment screening at AstraZeneca: developing the next gene..:

Lucas, Simon C. C. ; Börjesson, Ulf ; Bostock, Mark J....
RSC Medicinal Chemistry. 13 (2022) 9 - p. 1052-1057 , 2022

Link: https://doi.org/10.1039/..

6

Dynamics of the HD regulatory subdomain of PARP-1; substrat..:

Ogden, Tom E H ; Yang, Ji-Chun ; Schimpl, Marianne...
Nucleic Acids Research. 49 (2021) 4 - p. 2266-2288 , 2021

Link: https://doi.org/10.1093/..

7

Generating Selective Leads for Mer Kinase Inhibitors—Exampl..:

Nissink, J. Willem M. ; Bazzaz, Sana ; Blackett, Carolyn...
Journal of Medicinal Chemistry. 64 (2021) 6 - p. 3165-3184 , 2021

Link: https://doi.org/10.1021/..

8

Regenerable Biosensors for Small-Molecule Kinetic Character..:

Gunnarsson, Anders ; Stubbs, Christopher J. ; Rawlins, Philip B....
SLAS Discovery. 26 (2021) 5 - p. 730-739 , 2021

Link: https://doi.org/10.1177/..

9

Free energy perturbation in the design of EED ligands as in..:

O' Donovan, Daniel H. ; Gregson, Clare ; Packer, Martin J....
Bioorganic & Medicinal Chemistry Letters. 39 (2021) - p. 127904 , 2021

Link: https://doi.org/10.1016/..

10

Optimization of an Imidazo[1,2-a]pyridine Series to Afford ..:

McCoull, William ; Boyd, Scott ; Brown, Martin R....
Journal of Medicinal Chemistry. 64 (2021) 18 - p. 13524-13539 , 2021

Link: https://doi.org/10.1021/..

11

A-loop interactions in Mer tyrosine kinase give rise to inh..:

Pflug, Alexander ; Schimpl, Marianne ; Nissink, J. Willem M....
Biochemical Journal. 477 (2020) 22 - p. 4443-4452 , 2020

Link: https://doi.org/10.1042/..

12

Complexities of a protonatable substrate in measurements of..:

Swain, Brendan M. ; Guo, Dawei ; Singh, Himansha...
Scientific Reports. 10 (2020) 1 - p. , 2020

Link: https://doi.org/10.1038/..

13

Rapid Identification of Novel Allosteric PRC2 Inhibitors:

Read, Jon A. ; Tart, Jonathan ; Rawlins, Philip B....
ACS Chemical Biology. , 2019

Link: https://doi.org/10.1021/..

14

Antibody fragments structurally enable a drug-discovery cam..:

Luptak, Jakub ; Bista, Michal ; Fisher, David...
Acta Crystallographica Section D Structural Biology. 75 (2019) 11 - p. 1003-1014 , 2019

Link: https://doi.org/10.1107/..

15

Discovery of Mcl-1-specific inhibitor AZD5991 and preclinic..:

Tron, Adriana E. ; Belmonte, Matthew A. ; Adam, Ammar...
Nature Communications. 9 (2018) 1 - p. , 2018

Link: https://doi.org/10.1038/..