E-LIB Suche - Ergebnisse für: Ruggeri, Roger B.

1

6-Azaspiro[2.5]octanes as small molecule agonists of the hu..:

Aspnes, Gary E. ; Bagley, Scott W. ; Coffey, Steven B....
Bioorganic & Medicinal Chemistry Letters. 94 (2023) - p. 129454 , 2023

Link: https://doi.org/10.1016/..

2

Small molecule inhibitors of PCSK9. SAR investigations of h..:

Aspnes, Gary E. ; Coffey, Steven B. ; Darout, Etzer...
Bioorganic & Medicinal Chemistry Letters. 92 (2023) - p. 129394 , 2023

Link: https://doi.org/10.1016/..

3

Bioorthogonal Tethering Enhances Drug Fragment Affinity for..:

Mattheisen, Jordan M. ; Limberakis, Chris ; Ruggeri, Roger B....
Journal of the American Chemical Society. 145 (2023) 20 - p. 11173-11184 , 2023

Link: https://doi.org/10.1021/..

4

A Small-Molecule Oral Agonist of the Human Glucagon-like Pe..:

Griffith, David A. ; Edmonds, David J. ; Fortin, Jean-Philippe...
Journal of Medicinal Chemistry. 65 (2022) 12 - p. 8208-8226 , 2022

Link: https://doi.org/10.1021/..

5

Discovery of High-Affinity Small-Molecule Binders of the Ep..:

Londregan, Allyn T. ; Aitmakhanova, Karlygash ; Bennett, James...
Journal of Medicinal Chemistry. 66 (2022) 1 - p. 460-472 , 2022

Link: https://doi.org/10.1021/..

6

Discovery of N-(piperidin-3-yl)-N-(pyridin-2-yl)piperidine/..:

Londregan, Allyn T. ; Aspnes, Gary ; Limberakis, Chris...
Bioorganic & Medicinal Chemistry Letters. 28 (2018) 23-24 - p. 3685-3688 , 2018

Link: https://doi.org/10.1016/..

7

Comparative pharmacokinetic profile of cyclosporine (CsA) w..:

Price, David A. ; Eng, Heather ; Farley, Kathleen A....
Organic & Biomolecular Chemistry. 15 (2017) 12 - p. 2501-2506 , 2017

Link: https://doi.org/10.1039/..

8

Liver‐Targeted Small‐Molecule Inhibitors of Proprotein Conv..:

McClure, Kim F. ; Piotrowski, David W. ; Petersen, Donna...
Angewandte Chemie. 129 (2017) 51 - p. 16436-16440 , 2017

Link: https://doi.org/10.1002/..

9

Liver‐Targeted Small‐Molecule Inhibitors of Proprotein Conv..:

McClure, Kim F. ; Piotrowski, David W. ; Petersen, Donna...
Angewandte Chemie International Edition. 56 (2017) 51 - p. 16218-16222 , 2017

Link: https://doi.org/10.1002/..

10

A Small-Molecule Anti-secretagogue of PCSK9 Targets the 80S..:

Petersen, Donna N. ; Hawkins, Julie ; Ruangsiriluk, Wanida...
Cell Chemical Biology. 23 (2016) 11 - p. 1362-1371 , 2016

Link: https://doi.org/10.1016/..

11

Truncated Glucagon-like Peptide-1 and Exendin-4 α-Conotoxin..:

Swedberg, Joakim E. ; Schroeder, Christina I. ; Mitchell, Justin M....
Journal of Biological Chemistry. 291 (2016) 30 - p. 15778-15787 , 2016

Link: https://doi.org/10.1074/..

12

Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo..:

Ruggeri, Roger B. ; Buckbinder, Leonard ; Bagley, Scott W....
Journal of Medicinal Chemistry. 58 (2015) 21 - p. 8513-8528 , 2015

Link: https://doi.org/10.1021/..

13

Cyclic alpha-conotoxin peptidomimetic chimeras as potent GL..:

Swedberg, Joakim E. ; Schroeder, Christina I. ; Mitchell, Justin M....
European Journal of Medicinal Chemistry. 103 (2015) - p. 175-184 , 2015

Link: https://doi.org/10.1016/..

14

Improving on Nature: Making a Cyclic Heptapeptide Orally Bi..:

Nielsen, Daniel S. ; Hoang, Huy N. ; Lohman, Rink‐Jan...
Angewandte Chemie International Edition. 53 (2014) 45 - p. 12059-12063 , 2014

Link: https://doi.org/10.1002/..

15

Improving on Nature: Making a Cyclic Heptapeptide Orally Bi..:

Nielsen, Daniel S. ; Hoang, Huy N. ; Lohman, Rink-Jan...
Angewandte Chemie. 126 (2014) 45 - p. 12255-12259 , 2014

Link: https://doi.org/10.1002/..